r/GHB_info

Is it better so use benzos to sleep rather than redose at night?

Hello.

I have been infrequently using gbl for about 3 years with pauses in between that usually last a month or so.
In the beginning I would only use for 3 days straight (if I woke up at night aswell) but then stopped cold turkey and suffered a bit at work because of the rebound but nothing a shot of vodka or a benzo couldn't help with.

Then my usage started to escalate. The thing is my relationship with G is such that once I start, I can never do just a dose or two, it always ends up in a bender that lasts a few days and in the end I don't even feel high from it, I just have to take it to not feel withdrawals and basically purely out of fear itself.
So I usually do benders that last 6-12 days during which I use around 18-25 ml a day. Then I get off it with the help of pregabalin and diazeam/clonazepam.

I have a bender coming up on vacation, don't ask me why, I just know I do because of the circumstances and because whenever there is G available (I never keep it at home for that reason) I can't resist it.

Usually the problem is that the "sleep" I get on G, no matter the amount is never really restful, so I was wondering if perhaps it would be better to dose during the day and take a benzo to sleep at night?

I was told this is better for the CNS because at least you get some proper sleep. And the daily ml consumptions is smaller.

After this bender I'm going to try being sober for a few months over the summer and battle my other gaba addictions and do proper neccessary tapers.

What do you guys think?

Thank you for your input and all the best to everyone out there, stay safe!

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u/loveiseverywhere23 — 4 days ago

Asking dr for a baclofen script?

I’ve been sober for the most part the last 10 months but I keep relapsing on GBL. I had a bad dependency a year ago and withdrawal was hell. Every time I relapse even after months of no use, I go back to having severe withdrawal symptoms after just one use. It’s extremely destabilizing and I’ve been wanting to get a baclofen prescription but I don’t know how to. Every time I see a doctor for literally everything I get immediately shut down so I’ve been extremely hesitant to bring up baclofen to my doctor.

The other issue is that I can’t exactly say anything about relapsing on GBL. I see my doctor each month for my suboxone prescription and opening up about using GBL would put that at risk. My doctor also has no idea about my previous dependence on G and is only aware of my addiction history with opioids.

How should I go about this? I was prescribed baclofen shortly when I was in rehab and it worked amazingly. Should I just say that my cravings have returned just for a specific substance and that I would like to address this as a preventative measure? She does psychiatric medicine and isn’t specialized in addiction so I doubt that she’s familiar with off label use of baclofen or even knows what GBL/ghb is.

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u/Alarming-Garden-2911 — 5 days ago

On the recent german GBL ban again

i have made a post like a month ago about the german GBL ban that happened on i think april 15th?

My stash is running low, the main source for paint remover has announced a new product in 7 days (for a month). I just looked into deep/dark prices, those are ridiculous...Faking a company in germany or getting my neighbor who owns a beauty salon to order something like that for me is both borderline impossible lol.

whats the move i ask?

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u/WilligeStute — 8 days ago

Experiences with 1,4 BD strictly for sleep?

Guys, I’m struggling a lot with my severe insomnia and fasciculation syndrome (which is linked to sleep deprivation and gets worse when I don’t sleep well).

Right now I’m relying on antipsychotics but they destroy me psychologically after a few days of usage and not to mention the long list of side effects they have, which include prolonged QT syndrome, which can cause deadly arrhythmias. And for a year now I started to have heart palpitations so I’m super cautious now with these drugs.

So because it’s impossible for me to get pharma GHB in Xywav, I’m thinking about trying BD again. I’m suffering with this syndrome for 8 years now and I know that to get better I need to sleep at an appropriate time and for enough hours, which unfortunately for me is 9 hours.

I used NaGHB but was only getting 2-3 hours max per 4.5g dose and was having to take 4 doses to get the 9 hours and feel better but it’s way too much sodium and I had high blood pressure, so I had to stop using it. But it was working tremendously for the insomnia and the sleep. It was something that I could rely on knowing that it would work.

Talked with nearly all the vendors on DW and no one has K-GHB nor were willing to try and make it. So what’s left is trying BD again, even if it’s just occasionally.

Does anyone here have experience with BD strictly for sleep or at very moderate doses? Cause I know some people claim no side effects with it and also say side effects might be from impurities and not from BD it self.

There’s also 1,3 BD which is now sold in beverages (Ketohol) and it’s literally the same as 1,4 but it gets converted into BHB in the liver instead of GHB. If you research you’ll see that 1,4 BD is not for human consumption because it turns into GHB. But we know GHB is non-toxic at therapeutic doses.

I’m not here promoting 1,4 BD, I’m just asking questions cause I’m really struggling to get my life back. Benign fasciculation syndrome is no joke, the neuropathic pain and twitching are horrible, not to mention I also developed weakness.

Thanks.

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u/yshcrp — 10 days ago

Health issues while using 1,4b?

I was addicted to 1,4b from September 2024 until the week before Christmas and unfortunately ive ended back on it again. For the last half of last year I had excruciating back pain and what i described as 'the feeling of the worst sunburn you've ever had in your life' all over my forehead.

Once i stopped using that all went away. Now im back on it its all come back, along with shin splints so bad that i struggle to walk. Im seeing my doctor for baclofen and valium next week (I cant get in sooner) but the pain is excruciating.

Has anyone else experienced this?

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u/Dragoonie_DK — 11 days ago

How long after taking a dose of BDO can I have alcohol?

Hello I took 2ml BDO this evening and I’m wanting to have 3-4 drinks with friends tonight. So say BDO at 5pm. Can I drink at 11pm?

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u/PharmaFingers — 11 days ago
▲ 2 r/GHB_info+1 crossposts

Grok: Which is worse for the liver, alcohol or 1,4 BD?

Alcohol (ethanol) is generally much worse for the liver than 1,4-butanediol (1,4-BD), especially with chronic or heavy use. pubmed.ncbi.nlm.nih.gov

Alcohol (Ethanol) and Liver Damage

Ethanol is a well-established hepatotoxin. Chronic heavy consumption leads to:

• Alcoholic fatty liver (steatosis), alcoholic hepatitis, fibrosis, and cirrhosis.
• It causes oxidative stress, inflammation, fat accumulation, and cell death in the liver via metabolism (primarily by alcohol dehydrogenase and aldehyde dehydrogenase, producing acetaldehyde and reactive oxygen species).
• Epidemiology: Alcohol-associated liver disease (ALD) affects millions globally (prevalence around 4-5% in general populations, much higher in heavy drinkers). It accounts for a large share of liver disease deaths, cirrhosis cases, and transplants. Mortality rates have risen significantly in recent years. pubmed.ncbi.nlm.nih.gov
This is dose- and duration-dependent, with risks escalating over years of regular heavy drinking. Many people develop irreversible damage.

1,4-Butanediol (1,4-BD) and Liver Effects

1,4-BD is an industrial solvent and GHB precursor. It is metabolized in the liver primarily by alcohol dehydrogenase (ADH) to gamma-hydroxybutyraldehyde, then to GHB (via aldehyde dehydrogenase). This shares metabolic pathways with ethanol, leading to competitive inhibition when both are present. pmc.ncbi.nlm.nih.gov

Evidence on hepatotoxicity:

• Animal studies (e.g., rats) show mild-to-moderate liver inflammation or minor changes at high doses (e.g., 500 mg/kg), but not severe or statistically strong organ-specific toxicity in subchronic studies. No strong carcinogenic signal. ntp.niehs.nih.gov
• In human recreational/chronic misuse (often high/frequent doses), reports mention toxic hepatitis as a complication, along with other organ effects (kidneys, heart, etc.). This occurs in the context of heavy polydrug or compulsive use. pmc.ncbi.nlm.nih.gov
• Acute overdoses can cause severe effects (respiratory depression, coma, death), sometimes mimicking toxic alcohol poisoning, but liver damage is not the primary acute feature. Co-ingestion with ethanol can worsen outcomes, including increased mortality and tissue damage in animal models (due to competition for ADH, leading to higher levels of the parent compound or altered kinetics). pubmed.ncbi.nlm.nih.gov

1,4-BD lacks the extensive long-term population data of alcohol; use is less common and often episodic or addictive in specific contexts rather than a daily societal norm.

Key Comparison and Caveats

• Chronic exposure: Ethanol has far stronger, dose-dependent evidence for progressive liver scarring and failure. 1,4-BD can contribute to toxic hepatitis in heavy users but appears less potent per se for long-term fibrotic/cirrhotic disease.
• Acute/high-dose: Both are risky; 1,4-BD has a narrower therapeutic window for CNS/respiratory depression (via GHB), and mixing with alcohol is particularly hazardous. nejm.org
• Individual factors: Genetics (e.g., ADH/ALDH variants), dose, frequency, nutrition, and co-exposures matter for both. Neither is “safe.”
• Neither is recommended: 1,4-BD is not for human consumption and carries risks of addiction, overdose, and multi-organ toxicity.

Bottom line: Alcohol poses a substantially greater overall risk to the liver due to its prevalence, well-documented chronic effects, and public health burden. 1,4-BD is toxic (especially acutely or in combination), but not a comparable driver of widespread liver disease.

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u/yshcrp — 14 days ago

The final battle

30 y/o F, using BDO 3 years on and off caught in cycle of detox out patient then relapse then back to detox.
I’ve had enough. Detox said we won’t let you do this again you need to go to the hospital next time. Long story short I’ve gotten hold of 100x 10mg baclofen and 50 x 5mg diazepam. I will have someone to monitor 24/7 each weekend then after 6 weekdays (my ex partner works). I also use meth (8 year battle) but have hit my lowest low and want out. I’ve got nothing left. My care team says it’s too risky doing outside of a hospital setting but I think because I’ll have spoken there 24/7 Saturday and Sunday I’ll be okay? I should be right.

Currently using 3.6 ml every 2-2.5 hours, blacking out, 24/7 use for solid 4 months (hell on earth) I sleep 2 hours at a time but alas I wake up to anxiety and withdrawal symptoms and dose myself 2-3 ml to go back to sleep. So nothing solid over 3 hours ever without dosing. Usually go days without solid blocks of 2 hour sleep dose sleep dose cycle.

Advice?
Schedule?

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u/alleeeram — 14 days ago