r/HashimotosGLP1

What is your dose at what intervals? 4 days? 5 days?

50 on HRT. 100mcg of levo. On tirz for 9 months now. Started at 2.5. Went up to 5.0 for 8 weeks but came back down due to weight loss. I wanted the autoimmune control not the weight loss. Down 45 lbs in 6 months, so i lowered my dose. I’m on 2.5 tirz every 7 days for the last 3 months. My weight has maintained. Here’s the issue, I’ve noticed an increase in my joint stiffness/pain. Bloodwork is spot on. No changes there.
This medication has been a lifesaver. Never coming off of it. I just want to make sure I am using it correctly to achieve the best results. Endo is helpful but he doesn’t actually know what it is like to live with autoimmune. Y’all do! It is a moving target.
My question is, if you experienced a plateau in the effectiveness of tirz on your Hashimoto’s and if so, what did you do? Did you split your dose? Up your dose? Or both? Did you find a sweet spot where you were able to maintain weight and inflammation?

Hi...just like the title says. My daughter was diagnosed with Hashimoto’s and is interested in trying microdosing GLP-1s for possible inflammation benefits. I’m curious what others are doing, specifically what medication you’re taking and at what dose.

Sometimes it gets confusing comparing doses because semaglutide and tirzepatide use different dosing scales, but all the numbers people mention (.25, .5, 1, etc.) start sounding the same after a while.

Also curious whether the thyroid warning concerns you at all with Hashimoto’s/hypothyroidism.

Thanks for any feedback .