r/IndianEnts

Found an interesting Nature report on how magic mushrooms (psilocybin) affects the human brain!

  1. This study found that psilocybin causes different brain regions to stop communicating in their normal way. The effect was so strong that the brain activity pattern of the same person on psilocybin became as if we are comparing two completely different people.
  2. People who had the strongest psychedelic experiences, showed the biggest changes in brain connectivity.
  3. Even after the drug effects were gone, the connection between the anterior hippocampus (memory/self-related region), and the Default Mode Network (DMN) remained reduced for weeks. Why this matters? Overactive DMN connections are correlated to depression. This explains the long-lasting antidepressant effects of psilocybin.

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Note: I don’t consume any magic mushrooms or any drugs. It’s simply an amazing study on how these alkaloids (tiny plants of mushrooms) impact communication between our neuronal connections. The findings really amazed me.

Reference: https://www.nature.com/articles/s41586-024-07624-5

u/NbOPO4 — 10 hours ago

Good trip turned bad

I was having a blast trip, good high then my friend who was driving my car collided with some dogs running and broke my front headlight. Turned whole fun to mess, nd being high I didn't even what I was feeling anymore, i couldn't even enjoy the music 😤, anyways.

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u/Perfect_Option5611 — 14 hours ago

New bud, new strain

Based on my analysis, looks of this and the high it gives me, my best guess would be cali type blue dream strains as this gives me a cerebral dominant and a long lasting high. I would love to hear what u guys think about these buds

u/Whatislife_06 — 15 hours ago

Dextromethorphan (DXM) Guide

DXM is readily available legal drug that you can find over the counter, it is mainly available in the form of cough syrups. The high is unique because it's drastically different depending on your dosage and it can be classified into four distinct plateaus such as:

  1. First Plateau (1.5 - 2.5 mg/kg) - The effects felt in the first plateau are usually not very intense. They can include but are not limited to: cognitive euphoria, increased music appreciation, time distortion, pupil dilation, and stimulation. First plateau is often described as a "drunk" feeling.
  2. Second Plateau (2.5 - 7.5 mg/kg) - This is the most recreational plateau. It is more sedating than stimulating, while euphoria and visual disconnection are more intense. Additional effects of the second plateau can include but are not limited to: wakefulness, physical euphoria, spatial disorientation, perception of bodily lightness, frame rate suppression, and increased music appreciation. Music is often reported to be greatly enhanced at this plateau, described as rich, clear, and amplified. (It rivals psychedelics in this aspect in my humble opinion)
  3. Third Plateau (7.5 - 15 mg/kg) - It is much more intense than the second, and should be gradually worked up towards. The effects of the third plateau can include but are not limited to: dissociation, sedation, nausea (during comeup), memory suppression and ego death, auditory hallucinations, internal hallucinations, cognitive dysphoria, euphoria, anxiety, delusions, and all the effects of the second plateau. The trip is very euphoric and profound. There is also an omnipotent feeling that one is in control of the entire universe, accompanied with CEVs. Closed eye visuals are often present, consisting of usually darker colored geometric patterns, vast landscapes, and scenes. Music can greatly enhance the effect, although it can also sound tinny and distorted. People have reported being able to break down every single fragment of a song and visualize all of it in their minds; reliving past memories has also been reported. The third plateau is often reported to be extremely introspective and a number of users describe being inspired to improve their lives. The afterglow is reported as tiring, but a mood boost is often reported for days or weeks afterward.
  4. Fourth Plateau (15 - 20 mg/kg) - The effects of the fourth plateau can include but are not limited to external hallucinations, complete dissociation, and all the effects of the third plateau, with greater intensity. Amnesia can occur, leading to memory blackouts or brownouts. (Not worth doing and very bad for your health in general)

To calculate your dosage according to your weight use this calculator.

How similar is it to Ketamine?

I would say the second and third plateau are very similar to Ketamine but Ketamine is just a very very cleaner high but more short-lived (when insuffulated) so it is more bareable and the side effects are almost non existent compared to DXM which causes a lot of body load and cognitive load.

How to get your hands on DXM?

I think the best way is to get your hands on pure DXM pills which are called DMR-30, they are the cleanest form and allow you to dose high. You can also get your hands on syrups, I avoid Benadryl DR which contains 300mg DXM because it's filled with laxatives and causes diarrhea, I would rather use something like Rexcof DX which has 200mg DXM and some CPM but keep in mind that extra ingredient is not good for you at all so I wouldn't take more than one cough syrup

Combinations with DXM?

  • Ket + DXM was just not fun at all, no synergy
  • LSD + DXM extreme synergy, extremely fun, borderline of ego death
  • Pregabalin + DXM produces closed eye visuals and out of body experience
  • Weed + DXM enhances dissociation to a great extent

Source: PsychonautWiki + Personal Experience

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u/greenmilegrassy — 14 hours ago

Some offbeat media for the stoners! An old issue and more for you to get lost in

High Times Magazine Archive

Among the several legalization efforts that started out as underground media to provide the counter-culture stories, features and so much more in the US.

u/Beyoume — 19 hours ago

will airport security detect that these are edibles?

these are rastafari gummies they look like chocolate a

u/Upbeat-Bank4444 — 1 day ago

Diced pineapples it sparks my imagination

yoga karo ganja peyo

u/Xyt0 — 1 day ago

My father caught me with this

2 days ago my father saw me receiving this in mail , he asked and i said meds hai Then again yesterday he took it from my room and googled it

Then said why are you doing drugs bla bla

And kept it 😭( probably tried it too)

And i had to manipulate him to get back my stuff 😂

Has anyone experienced this before?

I really can't focus on posting because the show is

my fav that I've been watching in my school after coming home, quickly freshen up to have my lunch alone in my room with just this sitcom.

Btw after taking a break of just around 11 months, I'm smoking.

I'll say it's a comfort show while smoking.

Idk if I'm just alone who thinks that or there are others...

u/vkas_exe — 1 day ago

Help me understand stuff I got is legit or spiked

What I got is OG... but I couldn't differentiate if this is legit or spiked... texture seems good. What I doubt is when I try to crush it with my fingers, I can feel it being converted to powder form. I can feel the smell is OG strong... is it fine? Anyone having good experience of OG here? I have been smoking for the past 6 months.

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Flying Internationally with Honest x Dynavap Butane Torch?

Are we allowed to fly internationally from IGI Delhi with a completely empty butane torch e.g. honest x dynavap torch (the $10 one)?

In case it matters, I'll fly with LOT.

Thanks!

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u/Actual_Stand4693 — 2 days ago