I was prescribed this medication and used it for years. However, I have a huge surplus, and not sure what to do with it.

I know exactly how expensive this medication is- as I loathe insurance about halfway through treatment and the kindest internet stranger sent me a month supply - gratis.

I’d love to pay it forward if I can. Any suggestions?

So we have gone to multiple hospitals but all have one doctor/expert for the respective illness. But our concern is that liver support medicine have bad impact on diebetes. each doctor will prescribe medicine as per one illness and look into the complete portfolio of disease in the body.

Please suggest what can be the best doctor/hospital in such cases.

Current Location , Mandsaur Madhya Pradesh. Traveling is fine for us. We have travelled till ahemdabad/udaipur till now.

Hi all, just a quick question for liver specialists as my GI hasn’t been totally knowledgeable about my condition.

I have some pancreas and GI issues after a bad bout of Covid and on an MRCP, they discovered 2 masses on my liver (that they think are adenomas). My GI asked me to do a liver specific MRI with eovist to check it and I am waiting for that in a month but my question in the meantime is why would someone like myself who has never even once been on birth control have 2 adenomas? And alternatively, is there anything I can do in the meantime to help them shrink? I work out but anything I can eat? Milk thistle? Avoid certain food groups etc? Is estrogen is boosting them from just my body’s hormonal supply and not BC, how can I keep that even keeled while I have my menstrual cycles? Any help would be appreciated.

Hi everyone. I’m a 22-year-old woman from Canada, and I’m sharing my story because my doctors say my case is unusual. I’m hoping someone here has gone through something similar because this has been the hardest experience of my life.
It all started when I had my gallbladder removed because of gallstones. I stayed in the hospital for two days after surgery and was discharged. The very next day, I developed severe pain in my upper right back and had to return to the emergency room. At that time, I had no idea my liver was involved.
They told me it was probably a muscle strain, gave me medication for muscle pain, and sent me home. The pain never really went away.
The next day I went back to the emergency room because I was still in severe pain. This time they thought it might be a kidney problem. They gave me medication and sent me home again, but nothing changed.
I returned to the emergency room a third time. They thought it might be related to my fatty liver. They treated my pain, including morphine, but I was discharged again. The pain kept getting worse.
By the fourth visit, I was desperate. I drove about 45 minutes to another hospital because the hospital in my hometown wasn’t finding any answers. Every time I went there, I was mostly left waiting and then sent home. When I arrived at the hospital in the other city, everything changed. I was admitted immediately, and I never went back home after that.
For almost 20 days, I was treated mainly with morphine because the pain was unbearable. At first I received IV morphine every two hours, and later I was switched to oral morphine every two hours. I also received medication for constant nausea and vomiting. About three days before I was discharged, I stopped taking the morphine because, for the first time, the unbearable pain had finally improved.
The strange thing is that after my gallbladder surgery, I actually felt okay for about a month. Then suddenly the pain returned, but this time it was much worse than before. It felt like my liver was on fire. I had severe pain in my upper right abdomen and back, constant nausea, vomiting, intense itching, and eventually my eyes turned yellow.
The doctors performed what felt like every possible test: countless blood tests, CT scans, MRI scans, and finally a liver biopsy because they couldn’t figure out what was causing my liver injury. They even considered autoimmune hepatitis.
When the biopsy results came back, I was told I had drug-induced liver injury (DILI), most likely caused by antibiotics I had taken before all of this happened. I was also told I already had fatty liver disease, and one doctor told me my liver looked like the liver of someone around 70 years old who had been drinking heavily for many years. Hearing those words at only 22 years old completely devastated me.
Since this all started, I have lost about 10 kg (22 lbs). Part of it was because I was so sick, and part of it has been from following a strict low-fat diet during my recovery.
My doctors told me my case is still not closed. They are referring me to a liver specialist in Vancouver because they feel my case is unusual for someone my age. I am still having frequent blood tests to monitor my liver. I have another blood test and an appointment with my doctor on the 13th to discuss my results and what happens next.
After I was discharged from the hospital, something else happened that frightened me almost as much as the liver disease.
I developed severe panic attacks.
I don’t know if it was because of everything I went through, the amount of morphine I received, or simply the trauma of the entire experience, but I couldn’t stop crying. I became terrified of hospitals. I couldn’t sleep. My mind never stopped racing. I had horrible thoughts and even visual hallucinations. I had to return to the hospital because I truly believed something was seriously wrong with me.
The doctors prescribed medication for anxiety/depression and medication to help me sleep. Thankfully those symptoms gradually disappeared, and I have now stopped taking those medications.
Today I’m much better than I was. My yellow eyes are gone. The itching has improved but still comes and goes. I still have mild discomfort (about 2–3/10) on my upper right side, especially after eating. It’s nothing like the pain that put me in the hospital, but it’s still there, reminding me that my liver is still healing.
I honestly just want to know if anyone has experienced anything similar.
• Has anyone here had DILI caused by antibiotics?
• Did anyone need a liver biopsy?
• Were you told your liver was severely damaged even though you were young?
• Did you continue having mild pain or itching during recovery?
• Did anyone experience panic attacks or severe anxiety after a long hospitalization or after receiving large amounts of morphine?
• How long did it take before your liver tests improved and you finally felt like yourself again?
Thank you so much for reading my story. This has been the hardest experience of my life. I truly felt like I was going to die, and now I’m just hoping to find someone who understands what I’ve been through.

​

Hello. Recently I read on the internet that a woman (Alice Burton Bradford) who ate very little died after consuming a small amount of alcohol, and that her friends said she definitely did not drink a lot, but that she had not eaten enough. I am aware that the internet does not provide all the information, but it still made me feel uneasy.

When I go out, I like to drink 3 to 4 cans of beer and it feels wonderful. However, I generally eat less, and in the past few months I have not been very regular or eating much due to obligations. Often I have eaten very little, but I still feel completely fine.

I have no known medical conditions and I do not drink often, only at concerts or live music events.

I am wondering whether there is a real risk for me. Sometimes I eat one meal a day, and sometimes a bit more. I am otherwise a slightly thinner person, but within normal limits.

I am also wondering under what circumstances alcoholic ketoacidosis occurs, and whether it is truly the result of reduced food intake and alcohol, or complete starvation lasting for several days. Everything I read online is unclear, and honestly I would like to hear your opinion.

Thank you in advance.

Hey everyone,

So I recently got an ultrasound given that I admittedly was a heavy drinker for many of my 20s. I also am skinny fat and am considered overweight. I just turned 30 (m) and here are what the results said:

“The liver is normal in size and increasing echogenicity.  No focal parenchymal abnormality demonstrated.

Impression: HEPATIC STEATOSIS

I know that means fatty liver but unfortunately my doctor won’t review it until next week and I know fibroscans will probably be the next step to assess the specific level of fatty liver I have.

That being said, should I be worried or does it seem like this may be a case of mild fatty liver that I can fully reverse with lifestyle changes?

Thanks.

I’m a 45yo F, healthy BMI. I exercise regularly but drink moderately, occasionally heavily (think 6-7 drinks during a night out with friends, or tasting a lot of wine during the wine festival ). My most recent blood work showed AST level of 47 and ALT level of 21. Other liver markers were within normal range. How worried should I be about the high ratio (2.24)? Should I quit drinking and get retested at some point? I haven’t had a chance to talk to my doctor about it yet.

I was recently diagnosed with alcoholic fatty liver disease, and I plan on abstaining from drinking for several months (33 days sober currently) to allow time for my liver to heal back to its normal state. I totally understand the best option for me is to continue to abstain for the rest of my life, and I’m seriously considering it at this point, but I’m curious: since my liver has already sustained serious damage, will I be more susceptible to a more rapid progression of liver disease as a result if I do end up drinking again after I recover?

I drank heavily for six years with few breaks longer than 2 weeks (maybe 4-5 instances lasting longer than that) in that time. Would “round 2” likely move on a faster timeline than the first go around if I were to pick up that same habit again?

Age: 26
Height: 6’0”
Weight: 190lbs
Prescriptions: omeprazole
Smoking: on again, off again e-cigarettes. Most recently off of it for 9 months before picking it up recently to manage the alcohol cravings. I plan to stop in the next few days
Supplements: magnesium, l-theanine, l-lysine, milk thistle, glutathione, probiotics, fish oil, zinc, ashwagandha

Ive been having bad indigestion and belching for about a year, with occasional heartburn. In the past few months I've had increased upper right quadrant pain, radiating around my side and into my back and right shoulder blade. It often feels like something is stuck right beneath my ribs on my right side beneath my arm. Pcp prescribed Omeprazole and when sucralfate and when those didn't help referred me to GI. Had normal endoscopy.

Last week I ended up going to the ER for the sharp right side rib pain and nausea, along with squeezing pain right in the center of my stomach beneath my sternum. CT scan in ER was normal, as was blood work, except for some low globulin levels. ER ordered a follow up ultrasound. That ultrasound said gallbladder was normal but gave the following results for liver: "impression: Diffuse coarse and heterogeneous echogenicity in liver may represent a hepatocellular disease, such as cirrhosis or hepatitis."

No one from the hospital or my PCP or GI doctor has commented on this ultrasound report (I've just seen it in MyChart). My question is, are these symptoms related to this comment about my liver? What does it mean? Is there a chance this is still gallbladder related, should I ask GI Dr for a HIDA scan??

I'm just frustrated that none of my doctors seem to want to talk to me about it. Meanwhile I'm still nauseous every day, with occasional right sided discomfort and the abdominal squeezing pain. Nothing is debilitating but I'm definitely losing weight because of not wanting to eat much. I'm sick of feeling crappy 😵‍💫 would love to hear what it ended up being for anyone who has had a similar situation!!

Hey there,

Apologies for the long post.

Just a little background... A good friend of mine (36M) unfortunately requires (required) a liver donor. Approximately 6 weeks ago I (38M) told him I would be willing to donate and started the process. I was a blood type match and began abstaining from alcohol cigarettes and THC. I wouldn't say I'm an alcoholic but I definitely would enjoy drinks with friends on the weekends. Also the occasional cigarette and THC edible. No prior health conditions.

I'm just about at the point where the donor team wants to bring me to the other side of the country to run all the deep tests now that it's been over a month since I've been abstaining. Specifically they said they would reach out on July 11th to see if I would like to proceed.

In really awesome and exciting news... My friend was just recently (2 days ago!!!) was able to successfully get a deceased donor transplanted and is currently undergoing recovery. (HUZZAH!) We are all super happy for him and keeping our fingers crossed that everything takes nicely. Apparently the surgeons are saying he's doing better than about 90% of their liver transplants... Not sure if they're saying that just to be optimistic but it sounds promising. :)

Here's my dilemma/concerns.

Myself my wife and our friend group are all folks who enjoy our libations together especially on holidays. This weekend for the 4th of July we were planning on doing an out of town visit to a city we've never been to where we will be going to my other good friends Aunt and Uncles cocktail lounge (tickets and hotels were booked way prior to me figuring out that my friend needed a liver transplant and I began my abstaining from aforementioned substance).

At the very least I would really like to have a sip or two of their cocktails to try out the place as I've never met them and never been to their place before.

I would love to try some of the cocktails at their fancy cocktail place... But I just have these thoughts...

-"What if my friend rejects his new liver? If I have a drink or two is this going to completely reset my "donor testing" clock?"

-At what point should I say, "I think it's unlikely he will still need mine"?

-Even if I did have a few drinks this weekend would he even be able to undergo a new surgery this soon after his last?

My wife is of the opinion that realistically having a drink or two over the course of 2 days isn't going to have any reasonable impact on my liver health... But I'm also thinking that this might risk me being disqualified from a donor perspective if the absolute worst case happens and he experiences acute rejection and I need to fly out quickly.

Any thoughts and expertise are appreciated on this.

I got my blood work taken after a period of 5 years of not taking. Currently in early 20s. AST 450 , ALT 800-950. What could be the cause of this. I’ve gotten 2 scans, several blood tests. I love a very active life style, eat the most clean Whole Foods. Most of my family is healthy. No symptoms. What can be the cause of this.

Female 31 80kg

Vitamin D deficiency of 20 led to liver panel which shown elevated alt of 79.

3 months on vitamin d then liver function advanced panel taken

Results are smooth muscle antibody positive 1:200

Also had a positive 1:80 in 2018 no known cause found at that time.

GGT 259

Enzymes returned back to normal on this test. On previous tests they go up and down.

Have had a mild liver ache which i put down to gallbladder removal 5 years ago. When taking paracetamol or naproxen for other health conditions I get liver pain. Similar to milder version of a gallbladder attack.

Reduced pain relief to one dose a day and have done this for two years.

Had a referal to hepatology. Still waiting.

History of autoimmune type issues recurrent infections rashes etc. Immunology could not find a cause back in 2020.

Could someone please shed some light on to what may be happening and whats to come. I know autoimmune hepatitis is in question with a high smooth muscle like this.

Is it possibly lupus or a wider systemic auto immune issue or likely to be auto hepatitis due to smooth muscle positive and ANA negative.

Thanks

“This” close to losing him last week. At Sutter downtown, raced there to MICU from Auburn via ambulance. Due to projectile vomiting pure blood (alcoholic related esophageal varices), 5 days in MICU. Survived. Now angry and shutting out everyone except his landlord/best friend.

I’m looking for words of encouragement and support. I am attending Al-Anon meetings.

Hey! Recently I went in for routine blood work and got that my ALT was 102 and AST was 63, everything else was fine including other liver indicators. After getting retested five days later, both liver enzymes dropped No diabetes or significant cholesterol. I’m 20F and otherwise healthy with no family history of liver issues or autoimmune. I‘ve been taking ibuprofen a little more than often in the past month or two due to getting sick and wisdom teeth. Also took amoxicillin and dexamethasone for wisdom teeth a month ago, and taking zyrtec, vitamin b, zinc, and vitamin c supplements. My PCP does not think it has to do with these medications. They brought up it possibly being autoimmune hepititis due to my age and gender. Now I’m just waiting for the autoimmune tests which still haven’t come out yet despite the others already being out and normal, so I‘m very anxious. I guess for more certainty I was wondering if anyone has been in a similar situation and is willing to share their experiences?

Update: all tests returned normal including anti smooth muscle and anti mitochondria!

(I did read the community highlights which I found very helpful, this is more specific to my circumstance).

On Wednesday I went to the ER for a distended stomach that lasted 3 weeks. After some tests, especially the catscan and ultrasound, I was told it’s cirrhosis and to go to a specialist.

Long story short, insurance made it complicated and now it’s Saturday. I can’t make an appointment with the specialist until Monday, and I feel stuck in more ways than one.

More urgently, I am miserably uncomfortable and in so much pain. They didn’t drain any of the liquid, which they said was aceites, and it’s hard to breathe deeply, cough, sleep, or even move normally. It hasn’t gotten worse since the ER, and I told them all of this at the time. Maybe it’s normal they didn’t? Idk, I don’t want to go back to the ER, mostly because who knows how much that would cost me even with insurance, but I’m going on week 4 of feeling like a watermelon was implanted into my abdomen, and it’s consuming my life.

Less urgently, more generally, what should I expect for my first appointment with the specialist?
Will they run more tests?
Will they give me a diet plan?
What sort of numbers and scores and “stats” or whatever will I be given?
What’s to be expected if I’m stage 4?
Am I pretty much guaranteed to be stage 4 since I waited until symptoms became unbearable?
Will I be given a timeframe for life expectancy?

For personal context, someone mentioned on here how unfair it felt compared to other people in their life, and thats spot on for me. I know so many people who drink so much more than me, who started drinking so much earlier than I did.
I know dwelling doesn’t help, but fuck, that’s frustrating as hell.

Anyway, any personal advice, anecdotes, stories, are all welcome.

(ETA: in case it’s relevant or anyone cares;
35f, I drank excessively for 5 consecutive years. Prior to that, I only drank with friends and never daily)

UPDATE: The ER sent me home :(
They said since my vitals are good and I don’t have a fever etc, the liver specialist needs to be the one to drain it for diagnostic reasons. They called it an “elective procedure” because I was requesting it for “comfort”. I emphasized the fact that it had been over 3 weeks without any draining, and the difficulty breathing, but that changed nothing. At least I tried, thank you everyone for the encouragement.

Hey! Recently I went in for routine blood work and got that my ALT was 102 and AST was 63, everything else was fine including other liver indicators. No diabetes or significant cholesterol. I’m 20F and otherwise healthy with no family history of liver issues or autoimmune. I‘ve been taking ibuprofen a little more than often in the past month or two due to getting sick and wisdom teeth. Also took amoxicillin and dexamethasone for wisdom teeth a month ago, and taking zyrtec, vitamin b, zinc, and vitamin c supplements. My PCP does not think it has to do with these medications. They brought up it possibly being autoimmune hepititis due to my age and gender. I just did more blood tests, but I‘m very anxious. I know this is not the place to ask for a diagnosis, but I guess for more certainty I was wondering if anyone has been in a similar situation and is willing to share their experiences?

Update: all my tests came back negative which should be good news!

I’m 41 years old, 6’5”, and weighed 535 lbs when all of this testing was done.
I’m wondering if anyone has been diagnosed with cirrhosis or advanced fibrosis and later found out it wasn’t as bad as originally thought.
Here’s my story:
Back in 2020, I started having a dull ache in my upper right abdomen. My primary care doctor ran blood work, and everything came back normal. An ultrasound showed fatty liver. They ordered a HIDA scan, which showed my gallbladder was only functioning at 4%, and I was told I needed it removed. Unfortunately, this was during COVID when elective surgeries were postponed, and I never had it taken out.
I should also mention that for years I was a heavy drinker about three times a week, so I know alcohol may have contributed in addition to my weight and fatty liver.
Over the years, doctors basically dismissed the fatty liver diagnosis because my labs were always “great,” and I was told not to worry about it.
Fast forward to recently: the pain in my right side gradually got worse, so my primary doctor referred me to a gastroenterologist.
The part that’s confusing me is that my liver blood work has always been normal. My ALT, AST, bilirubin, albumin, INR, BUN, and platelets have consistently been within normal ranges. The only abnormal liver enzyme I’ve ever had was in 2014 when my ALT was 81 and AST was 22.
Recent testing showed:
Ultrasound: liver span 25.0 cm, increased parenchymal echogenicity, nodular liver margin, portal vein diameter 1.7 cm with normal flow.
FibroScan: CAP 359 and liver stiffness 26.9 kPa.
The gastroenterologist told me I have “early-stage cirrhosis, late fibrosis” (those were her exact words). I don’t have any symptoms of liver failure, and I go in July for an endoscopy.
One thing I’m also wondering about is whether my FibroScan could have been affected because I drank pretty heavily for the two days leading up to the test. My liver was also enlarged/inflamed at the time. I’ve read that inflammation can sometimes increase liver stiffness measurements.
Has anyone here had a FibroScan overestimate fibrosis or been diagnosed with cirrhosis and later found out it was less advanced after further testing (MRI, biopsy, repeat FibroScan, etc.)?
I’m not looking for false hope I know my obesity, fatty liver, and alcohol use all increase my risk. I’m just trying to understand whether misdiagnoses or overstaging happen before I assume the worst.
Thanks for reading, and I’d appreciate hearing about your experiences
I’m currently 35 days sober.

Im 24 years old, I have a lot of Fatigue and Brain Fog. Recently found out i have Fatty Liver with a Kpa score of 9.5 and CAP score of 357. I am overweight, My only question is it completely reversible with right diet and weight loss? Or is it permanent damage now? By reversible i mean will it be as good as any 24 year old has his liver? Or i have to take precautions all my life now?

F 30 265 lbs
Meds:
Gabapentin
Propanolol
Hydroxizine
TraZODone
Ambien just switched to Lunesta ( not working )
Abilify just switched to Lurasidone ( not working )
Venlaflaxine
LamoTRIgine
Lansoprazole
Infammatone
And magnesium glycinate
Also an IUD birth control

Resistant to GLP1, Phentermine pills, and Semaglutide injections

Elevated and quickly rising ALT, ALP, AST, and GGT levels.
A1C jumped from 5.3 to 5.7 in a month
Pre diabetic

Diagnosed: Bipolar, Depression, Anxiety, insomnia, sleep apnea, and I’m being tested for ADHD on Aug. 31,

I am diagnosed with Fatty liver disease, chostochondritis, chronic inflammation, and metabolic syndrome ( I forgot the last ones real phrasing, sorry )

Family history:
Lupus, Thyroid issues ( Hyperthyroidism I think) leukemia, breast cancer, skin cancer, lung cancer, and primary nervous system lymphoma, adhd, personality disorders, autism, fragile X, depression, anxiety, bad anger issues and diabetes.

I have Abdominal ultrasound photos as well as notes from the hospital.

My question is if anyone has an idea of some of the issues I’m having may be related to progression of liver disease, cirrhosis, liver failure etc.

Symptoms:
Mood swings,
euphoric mania,
suycidal depression,
crippling anxiety,
olfactory and auditory hallucinations,
brain fog, brain lag
Memory issues both short and long term
Impulse control issues
Possible OCD, that as a kid looked like anxious cleaning, that is now blemish picking and repeating words over and over again, and teeth grinding
Sleep apnea and horrible insomnia
Fatigue, no energy, feeling weak and slow
Pain. Every where. My chest, my arm, my head, my knuckles and ankles, and muscles in my legs causing twitching a lot at night. Randomly or at all times. I never knew the pain I’m in wasn’t normal until I saw my Dr.
vision darkens and gets blurry
Bad eye twitches and spinal shivers while driving
Feeling faint like everything pulses and sounds start sounding funny and I feel like the floor is moving in waves beneath me.
GI issues had bloody diarrhea for weeks, the blood has cleared up now but now it’s consistant diarrhea and never solid for at least the past year. I did have sticky looking clay like black stool 3 times. but that’s cleared up now as well.
Dark colored urine, likley dehydration
Easy easy bruising
I have an IUD, had one 12 years and now I just replaced it about 3 years ago.

And last but not least the most embarrassing.
I have been prone to UTI’s and Yeast infections since I was a kid. But right now it’s so different. Horrible smell that could probably make someone puke, and I feel like a dry tampon is stuck up there occasionally.
Someone at the hospital I was at had BV and now I’m wondering if it could be BV or if it’s liver related.
Washing won’t help, sometimes even worsens smell.
But there’s no pain, not even when I urinate, no bumps or warts or anything, and no itching.

Any ideas or input about all of this?
I can post Dr’s notes in the comments,
As well as my abdominal ultrasound.