r/PeptideLogbook

Image 1 — 12 months on retatrutide - down 35kg
Image 2 — 12 months on retatrutide - down 35kg
Image 3 — 12 months on retatrutide - down 35kg
▲ 405 r/PeptideLogbook+2 crossposts

12 months on retatrutide - down 35kg

Anxious for no real reason but here we are.

48 years old, started at the end of July 2025, second pic is exactly 12 months and 14 days later. Down 35kg total and actually put on a bit of muscle in the process which I honestly didn't expect.

Dosing:

  • July-Nov: started at 2mg, went up pretty slow, didn't hit 4mg until around week 16
  • Dec onwards: sat at 4mg for a while, bumped to 6mg around February and that's where I've stayed
  • Titrated slow on purpose bc I read too many horror stories about nausea and wanted to actually stick with it long term

Training:

Nothing fancy, just consistent. 4 days a week lifting (upper/lower split), started adding in incline walks around month 3 once the energy came back. Added actual running in December, could not even do 1km without stopping in November, ran my first proper continuous 5k in March in just under 30 min. Ridiculously proud of that tbh, more than the number on the scale honestly.

Food:

Started around 1600-1700kcal which was rough the first few weeks (side effects + deficit combo is not fun). Once appetite suppression kicked in properly it got way easier to sit there without white-knuckling it. Slowly brought it up to around 2000-2200 as activity increased.

Side effects:

Fatigue was the worst part for me, especially first 2 months. Some constipation early on, nothing crazy. Got bloodtests done at start and around month 9 nothing concerning, doc was happy with them.

Where I'm at now: dropped down to a lower maintenance dose just to hold where I'm at while I focus on building the running up and not losing more muscle. Eating closer to maintenance now too.

Thanks for reading, ask away if you've got questions, happy to answer whatever.

u/LittleSea7603 — 2 days ago

Starting GLP after stopping for ~14months

I started with a compounded version of Tirz over 2 years ago and was on them for about 8 months and hate a great experience. I stopped for personal reasons(fertility journey) and recently started Reta.

I am on my 3rd week; week 1 2mg, week 2 2mg, week 3 3mg and I have felt no change. I know Tirz and Reta do things differently but I expected to experience some of the same effects by now, even if minimal. My first experience with these drugs was taking Phentermine for a month and that was my intro to this type of drug and OH MAN my eyes were opened! I finally realized that this is how a lot of people live their lives! I loved it, which is when I decided to try tirzepatide and had a great experience on that too. So here I am, day 3 of my 3rd injection of 3mg and I still notice no change in appetite or food noise.

Part of me wants to jump to 6mg next week to almost feel some negative sides so I know what i'm using is good. Or should I just trust the process and the titration phase may take a little longer?

Side note because someone will probably ask, I sourced my GLP-3 Peptide from what seems like a reliable source and found some lab testing results on Janoshik but a part of me is still slightly skeptical.

reddit.com
u/waffle_stomperr — 2 days ago