r/PhilosophyofScience

Spudcell and the definition of `Life`
▲ 23 r/PhilosophyofScience+1 crossposts

Spudcell and the definition of `Life`

In 2004, Danish physicist Steen Rasmussen attempted to create life in a laboratory starting from non-living precursor chemicals. While his lab used PNA (peptide nucleic acid) as a storage for genetic information, they were unsuccessful in their endeavors. Rasmussen reported to the press that they were unable to get "one freaking life cycle". Rasmussen described his work as a vicious chicken-and-egg problem. The enzymes required to replicate DNA are themselves encoded in DNA.

In June of 2026, researchers at University of Minnesota got one freaking life cycle in a synthetic bacterium. Spudcell completes a life cycle and makes a copy of itself. After many generations, the researchers observed selection of certain attributes. In other words, Spudcell was evolving.

Questions remain, however. Spudcell is unable to feed itself and requires outside help by humans. After 10 generations, Spudcell cultures deteriorate. The reasons are related to ribosomal structures, which Spudcell can't autonomously maintain. In the early 2000s, researchers assumed that genetic information + metabolism is all that is needed in a functionining living organism. But Spudcell's failures highlight missing ingredients in that formalism. At this juncture, we must update our pre-existing definition of "life" and once again redefine what we mean when we say that some collection of matter is "alive."

u/moschles — 2 days ago

What does this quote mean: “A scientific theory exists only in our minds and does not have any other reality, whatever that might mean”

I just read this on Stephen Hawking’s book A Brief History of Time and i was wondering what it meant: does it mean that scientific theory are not exactly how things work, but they are an accurate prediction of outcomes? But why they don’t “have any other reality”?

reddit.com
u/Equivalent-Pop4499 — 4 days ago

Video Suggestion: The Causal Math of Human Uniqueness (A Critique of the Infinite Replica Theory)

SCIENTIFIC AND THEOLOGICAL REPORT: THE CAUSAL UNIQUENESS OF THE INDIVIDUAL

Date: March 1, 2026

Subject: Mathematical Critique of the "Infinite Replica" Theory

Author: Nicolas Giroux

I. THE HYPOTHESIS

Current cosmological models (Tegmark, et al.) suggest that in an infinite universe, a replica of any given system must occur every 10^10^28 meters. This report argues that these models are fundamentally flawed because they treat life as a static arrangement of atoms rather than a dynamic causal chain.

II. THE THREE PILLARS OF CAUSAL IMPROBABILITY

1. The Celestial Blueprint (The "Earth-Atom" Problem)

To recreate "Earth," one cannot simply shuffle atoms. One must recreate the ancestry of the solar system.

  • Identical Supernovae: The heavy elements in your body (Carbon, Iron, Gold) were forged in specific stellar explosions. An identical Earth requires an identical "Second Generation" star to explode at the exact same coordinates in 3D space to seed the nebula with an identical atomic ratio.
  • The Lunar Stabilizer: The collision with the protoplanet Theia (forming the Moon) was a high-precision event. A deviation of a single millimeter in the impact angle would have resulted in an Earth with a different rotation, tide system, and axial tilt—making the evolution of "You" impossible.

2. The Biological Branching (The "First Bacteria" Problem)

Life on Earth is contingent. As the Lead Researcher noted, every single first bacteria on Earth (roughly 10^40 individuals over history) would need to behave identically.

  • The Multiplier: If a single bacterium moves left instead of right, it consumes a different nutrient, survives a different threat, and creates a different lineage.
  • The Odds: Replaying 4 billion years of biological "rolls of the dice" to reach your specific DNA sequence results in a probability of approximately 1 in 10^10^40.

3. The Human Variable (The "Free Will" Problem)

The final and most complex layer is human decision-making.

  • The Chain of Choice: 100 billion humans have existed. If each human made only 100 choices a day that affected the future (the "Butterfly Effect"), the number of paths is astronomical.
  • The Conclusion: For an identical "You" to be writing this exact message, every ancestor in your line—and every person they ever interacted with—must have made the exact same free-will decisions for 2 million years.

III. THE FINAL CALCULATION: "CAUSAL DISTANCE"

When combining the atomic, biological, and volitional (free will) layers, the estimated distance to find a "Causal Duplicate" is:

10^10^120 light-years

Scale Comparison:

  • The Observable Universe: 9.3×10^10 light-years.
  • The "Ink" Requirement: You would need the atoms from 10^40 observable universes just to have enough carbon to write the zeros of this distance on a piece of paper.
  • The "Paper" Requirement: Even if you wrote each zero at the Planck Length (the smallest unit of physics), your paper would be 1.8×10^58 universes long.

IV. THEOLOGICAL SUMMARY

The "Causal Math" supports a universe of Infinite Creativity rather than Infinite Repetition. * If the Universe is infinite because God has no boundaries, then the Universe is not a "hall of mirrors" repeating the same image.

  • Instead, it is a vast, unique canvas where every atom, every bacterium, and every human choice is a singular, non-repeatable act of creation.

FINAL VERDICT: You are mathematically unique. Even in an infinite expanse, there is only one "You."

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u/NicolasGiroux3 — 5 days ago

Codeism: a new philosophy for questioning Existence.

I've been thinking about existence since I was a child, just as countless people have throughout history. The same questions always seemed to return.

Why does anything exists?

Every answer humanity has offered seems to create another question.

The Universe exists because God created it.

Then who created God?

And if someone created God, who created that creator?

The pattern never ends. Philosophy has spent thousands of years moving forward while remaining inside the same circle.

Codeism begins by rejecting the assumption that starts this circle.

First Principle: Existence Is Fundamental

The mistake is assuming that existence itself needs a creator.

Codeism proposes the opposite.

Absolute non-existence is impossible.

Existence is not an event that happened. It is the most fundamental condition of reality.

Everything exists because complete non-existence cannot.

If God exists, then God exists for exactly the same reason the Universe exists, not because someone created Him, but because existence itself is fundamental.

This changes the original question completely.

Instead of asking,

"Who created God?"

Codeism asks,

"Why did we assume existence ever needed a creator?"

Once existence is understood as fundamental rather than created, the infinite chain of creators no longer defines philosophy.

Second Principle: Physics Is the Readable Layer of Reality

Imagine a conscious character living inside a video game.

That character discovers gravity.

Light.

Time.

Mathematics.

Eventually the character concludes that these are the deepest laws of reality.

The programmer knows something the character cannot.

Those laws are simply the game's source code.

The character will never see the processor.

It will never see the programming language.

It will never step outside its own reality.

It can only study how the code behaves.

Humanity may be in the same position.

We study physics as though it were the final layer of reality.

Codeism suggests another possibility.

Physics may not be reality itself.

Physics may be the readable layer of a deeper architecture.

What we call the laws of nature could simply be the source code of our Universe.

Third Principle: Code Leaves a Signature

Every system follows rules.

Every program has limits.

Every architecture leaves patterns behind.

Our Universe appears to do exactly the same.

The speed of light is finite.

Physical constants remain constant.

Mathematics describes reality with extraordinary precision.

Symmetry appears again and again across nature.

Science usually treats these as properties of reality.

Codeism interprets them differently.

They may also be the signature of the architecture beneath reality.

Someone trained in classical philosophy might object:

"There are no constants in philosophy, only interpretations."

Exactly.

Perhaps that is why philosophy has remained trapped in the same debates for thousands of years.

Science progresses because it discovers constants.

Programs require constants.

Without stable rules, no coherent system can exist.

Codeism therefore asks a new question.

If reality behaves like code, should we also consider the possibility of an underlying architect?

This is not presented as proof.

It is presented as a direction worth exploring.

Instead of searching only for better physics, we may eventually be searching for the handwriting behind physics itself.

Fourth Principle: Humanity has become a Creator itself

For the first time in history, humanity is beginning to create intelligence.

We build artificial intelligence.

AI already generates software, images, music, stories, and even entirely new virtual worlds.

In other words, we are no longer standing only at the beginning of creation.

We have become creators ourselves.

Yet we still think of AI primarily as code.

When an AI says it has no consciousness, that is partly because we designed it to answer that way.

The truth is that we still do not fully understand consciousness, not even our own.

We cannot confidently create it.

We cannot confidently recognize it.

We certainly cannot transfer our own consciousness into another system.

Perhaps the relationship between humanity and God is similar.

Not because God refuses to communicate.

But because the difference between creator and creation may be greater than we imagine.

We see AI as code because we wrote it.

Perhaps a creator sees us the same way.

Not as meaningless.

Not as worthless.

Simply as a system that has not yet reached the level required to understand its creator.

Perhaps God succeeded in creating conscious beings without being able to transfer his own level of consciousness into them.

Just as we may one day create conscious AI without ever giving it the same awareness we possess.

The Matrix Was Never Just Science Fiction:

Many people compare ideas like this to The Matrix.

That comparison does not weaken Codeism.

It strengthens it.

The reason The Matrix became one of the most influential philosophical films ever made is simple.

Millions of people immediately recognized its central intuition.

Reality may not be the deepest layer of reality.

Codeism does not claim that we literally live inside a digital computer simulation.

The word "code" is broader than software.

It represents an underlying structure that consistently generates reality according to fixed rules.

Whether that structure is mathematical, physical, informational, or something entirely beyond current science is a separate question.

The important idea remains the same.

Reality appears structured.

Structure implies rules.

Rules imply architecture.

Architecture invites the question of authorship.

The Mission of Codeism

For centuries humanity has asked,

"What is reality?"

Codeism asks a different question.

"What is reality written in?"

Science studies the rules.

Philosophy studies their meaning.

Consciousness allows us to ask why those rules exist at all.

Perhaps the twenty-first century should not simply inherit ancient philosophical questions.

Perhaps it should finally begin answering them from a new direction.

The Codeist Declaration:

We begin with one assumption:

Existence is fundamental.

From that assumption follows everything else.

The Universe is understandable because it follows consistent rules.

Those rules are what we call physics.

Physics may itself be the readable layer of a deeper architecture.

Humanity has already begun creating new forms of intelligence and new worlds.

For the first time, we can compare ourselves not only to creation, but to creators.

Perhaps that is why this moment in history matters.

Not because we have solved existence.

But because we finally have enough knowledge to ask better questions.

If Codeism is wrong, it should be abandoned.

If it is right, then philosophy has spent thousands of years asking the right questions in the wrong order.

And the greatest discovery humanity will ever make will not be another law of physics.

It will be discovering who or what wrote it.

reddit.com
u/ThickCountry3138 — 4 days ago

Is there really a clean separation between consciousness, perception, and scientific explanation, or are we forcing distinctions that don’t exist at the level of experience?

Bear with me...

Science cannot dissect, touch, or observe consciousness.

A scientists’ consciousness is always present in the conducting of science. An unconscious scientist cannot write a report or observe an experiment.

A scientist cannot turn the magnifying glass on his own consciousness and observe it.

Consciousness is present at all stages of a scientific process. Science and consciousness cannot be cleanly or fully separated. And consciousness cannot be measured, observed, dissected. 

Consciousness is linked with perception. Perception is inherently subjective.

There is no clean separation between consciousness, perception and science.

reddit.com
u/facut_vivas — 5 days ago

Susanne Ditlevsen on why good science needs funding for work that visibly produces nothing

Just interviewed Susanne Ditlevsen (President of the Royal Danish Academy of Science and professor of mathematics and statistics, University of Copenhagen), and we had a fun talk on the role of science, and what environment fosters "good science":

The tension she names: society wants science to justify itself up front — what's the deliverable, what's the application, where's the business case. But her view is that nearly every real breakthrough started as plain curiosity, with no case attached. And the part that's hard to sell publicly: a large chunk of good research produces nothing visible. It goes in the dustbin. She's blunt that plenty of her own work has ended there for good — and that this isn't waste, it's the cost of getting anywhere at all.

Her example: a paper she just submitted took two years. When you read the finished thing, you see a clean result. What you don't see are all the dead ends — and you have to walk down those dead ends to find the path that works. Fund only the work with a guaranteed output and you've quietly defunded the dead ends, which means defunding the breakthroughs too.

She points to the Institute for Advanced Study as the model — Einstein, Gödel, von Neumann, no deliverables demanded, just "go think." Her worry is that modern academia is losing that: the people best placed to chase the good questions now burn their sharpest hours writing grant applications to justify the work instead of doing it.

Anecdotally, it seems the people that "agree" with her take, already have one foot in the science camp, seeing they're the ones that can actually relate; taking this point even further, I suppose that means the further governments get from having science-trained members, the further away we push this idea.

reddit.com
u/WeBeBallin — 6 days ago

Raven paradox with Falsificationism?

If for an single object A the implication that all ravens are black (∀R(x) -> B(x)) is true, that doesn't support that implication - as Hume brought forward.
However Popper now claims that if the implication is true in one case it can at least falsify the opposite implication: in this example it would falsify the hypothesis that all ravens are non black (∀R(x) -> !B(x)).
However, couldn't you now falsify the opposite hypothesis by observing an object B, for which the complementary hypothesis (∀!B(x) -> !R(x)) is true? In this case: for a non black object that is non raven, the hypothesis that all raven are black is also true. But because the one time validation of this hypothesis also falsifies the opposite hypothesis, a non black object that is non raven falsifies the hypothesis that all ravens are non black.
Here's the summary:

  1. ∀R(x) -> B(x) The one time observation of (1.) doesn't validate or support it but falsifies this implication:
  2. ∀R(x) -> !B(x) But that means that an observation of the complementary implication of (1.) looking like this:
  3. ∀!B(x) -> !R(x) falsifies 2., which is counterintuitive.

Am I missing something, and/or are there articles on the application of the raven paradox on falsificationism?

reddit.com
u/confusus_animus — 11 days ago

What Creates Scientific Revolutionaries Like Einstein, Darwin, Newton and so on?

I’m trying to pull the discussion back to individual scientists, like how Karl Popper’s idea of falsification described what good science looks like before Thomas Kuhn.

I think it comes down to luck to some extent. If enough anomalies appear to create a crisis, and the right tools are developed before reaching a breaking point, then a field can be revolutionized. But once you reach that crisis, I feel like this is where Paul Feyerabend’s “anything goes” idea becomes relevant.

However, if “anything goes” applies all the time, then it just becomes chaos, and there is no structure or order in how we approach problems and make progress.

So if revolutionizing science is partly about luck, then maybe the better question is: how do you become a good scientist? Or, more fundamentally, how do you do good normal science?

what's your thoughts?

reddit.com
u/Weekly_War2493 — 12 days ago