r/USPeptides

Hello,

I’m looking to see who has stacked these two peptides and your opinion on the effects. Given that dosing protocols are all over the place, I think I’ve settled on the following 8 week assessment as a beginner:

SS-31
Weeks 1–4: 5 mg daily
Weeks 5–8: 10 mg daily

MOTS-C
Weeks 1-4: 2.5 mg daily
Weeks 5-8: 5 mg daily

This is my first time using either and the first time stacking at the same time.

Any feedback is appreciated.

Thank you

Update:

It’s seems the consensus from user experience is 1mg SS-31 daily and to start at 1mg MOTS-C and titrate up from there.

Thanks to u/No_Management2698 for the video links. I learned quite a bit from Hunter Williams.

Thanks everyone.

Welcome to the weekly thread for the ladies of this community.

Most peptide info out there is geared toward men, and women's questions, dosing, hormones, weight, skin, mood, often get glossed over. This is the thread where they don't. Ask, share, and get real answers from other women who've actually run this stuff.

Whether you're fighting hormonal weight gain, battling breakouts, trying to lose the baby weight, riding out perimenopause, or just starting out, this is your space. Ask what you've been wondering. Share what's working. Tell us what you wish you'd known sooner.

This is the thread for what women actually come here to solve:

• "Which peptides actually work for hormonal weight gain that won't budge?"
• "What peptides clear hormonal acne?"
• "Which peptides actually tighten skin and smooth fine lines?"
• "What's helping with perimenopause and menopause, hot flashes, mood, sleep?"
• "Are GLP-1s like Reta safe and effective for women postpartum?"
• "What peptide stack helps a busy mom get energy back and still recover from training?"
• "How do I lose the post-pregnancy weight when nothing's moving?"
• "Which peptide finally burns stubborn belly and menopause weight?"
• "Which peptides help bring libido and drive back?"

Drop your question below. Ladies who've been at this a while, this is where we give back. Answer one question this week.

A Few Ground Rules

• No question is too basic. If you're wondering it, so is another woman reading quietly.
• Be specific. Your goal, age, where you are hormonally, and what else you're running all help us give you a real answer.
• This is education, not medical advice.
• New here? Start with the pinned Peptide Master Library and the Trusted Vendors List before you buy anything.

TL;DR: The weekly thread where women talk peptides, ask anything, and support each other, from weight and skin to hormones and menopause. No judgment. Jump in.

Not medical advice.

New to peptides? This is your thread.

Every week we run this thread so beginners have one place to ask anything without worrying about it being a dumb question. There are no dumb questions here. We all started at zero.

This is the thread for the stuff you might feel weird making a whole post about:

• "What should my first peptide even be?"
• "How do I reconstitute a peptide vial?"
• "What's bac water?"
• "What is a mcg vs mg or what is an IU?"
• "What should I take for fat loss?"
• "What needles do I use?"
• "What does a normal dose look like?"
• "Do I need bloodwork before starting?"
• "How do I read what's on the vial?"
• "Is this side effect normal or should I stop?"

Drop your question below. Veterans, this is where we give back. Answer one question this week.

A Few Ground Rules

• No question is too basic. If you are wondering it, three other people are too.
• Be specific.
• This is education, not medical advice.
• New here? Before you start researching, start with the pinned Peptide Master Library and the Trusted Vendors List.

TL;DR: Ask your beginner questions here. No judgment. Veterans, jump in and help one person this week.

Not medical advice.

[30F] pretty much what the caption says. Any females taking peptides for muscle growth? Any men willing to weigh in? Ive dived deep into fitness coming close to taking steroids but ultimately deciding against it due to not wanting any irreversible changes. Had a child, took a break, back into it and now that I’ve lost a good amount of weight I’m trying to decide what peptide to go on for muscle growth when I’m ready.

What are you taking? Pros/Cons, how significant is the muscle growth? I’m very aware this goes hand and hand with serious weight training and calorie/macro counting which I am no stranger to. Thanks in advance!

I’ve had a pretty good experience with Semax so far. I mainly noticed it seemed to help with mental clarity and focus without feeling overly stimulating. I really wanted to get off adderall, obviously nothing compares to that but it is helping and I can see myself getting off by using Semax 

I’m curious about trying Selank next, especially for the calmer/anxiety-support side of things without feeling amped up. I also recently saw a post about Adamax in here, so now that’s on my radar too.

For anyone who has tried Semax, Selank, or Adamax, how would you compare them?

Thanks

As a 52 yr old woman with an array of hormonal symptoms, what peptide have you found helps the most?

Symptoms, such as: dry skin, cellulite, weight gain, no libido, brain fog, fatigue/no energy, reduced motivation, muscle aches, thinning hair, saggy skin, night sweats, headaches, irritability, hard to lose weight, staying asleep, etc.

(I've been taking Tirzepatide for 3.5 months)

I've been reading through older peptide discussions and it seems like Tesamorelin and Ipamorelin get brought up together pretty often, especially when people are focused on body composition, recovery, and growth hormone support.

What I'm curious about is what people actually noticed after using them long enough to form an opinion.

Did one stand out more than the other in terms of results? Was there a noticeable difference in recovery, sleep, waistline changes, or overall training progress?

I know everyone's response is different, but I'm interested in hearing from people who spent at least a few months with one or both.

Why do i get so tired after using semax? Only on 250mcg dose.

Seeing progress from peptides? This is your thread.

Every week we’re going to run this thread so members have one place to share their wins, progress, and real-world results from peptides. Big or small, if something improved this week, drop it below.

This is the thread for results like:

“Down 4 lbs this week”
“My skin is finally clearing up”
“My appetite is way more controlled”
“My sleep has been noticeably better”
“My recovery has improved”
“My joints feel better”
“My tan is coming in”
“My before-and-after is finally noticeable”
“My physique is changing”
“My inflammation or bloating is down”
“I’m finally seeing results after staying consistent”

Pictures are encouraged if you’re comfortable sharing.

Progress photos, before-and-afters, skin improvements, tanning results, physique changes, scale changes, or anything visual helps the community learn and creates better conversation. You never know who your progress might motivate or help.

If you comment, feel free to include:

What peptide you’re using
How long you’ve been using it
What result you noticed this week
What changed the most
A progress picture if you’re comfortable
Anything you wish you knew before starting

A Few Ground Rules

No win is too small. If it mattered to you, it belongs here.
Be respectful. Progress looks different for everyone.
No source/vendor talk in this thread.
This is education and community discussion, not medical advice.

TL;DR: Drop your peptide wins below. Weight loss, skin, tanning, recovery, sleep, physique, healing, or anything else. Pictures are encouraged if you’re comfortable sharing.

Not medical advice.