r/fluvoxamine

Anyone on fluvoxamine and bupropion combination?
Rn Im on 50 mg Fluvoxamine alone in the morning but thinking of switching it at night as it cause me alot of fatigue and increasing it to 100 mg and adding 150 xl bupropion.
Previously I was on 150 xl bupropion and had good experience on it as it increased my libido motivation and fatigue
Anyone on this combo?
Please lemme know also I will consult with my doc about this

My stomach can’t handle the side effect my psy told me to stop taking it i am on day 2 off medication still feeling nauseous and stomach pain also no appetite is this normal ? What can do to flush detox .. i did take luvox only for 2 weeks first week 25 mg increase to 50 mg second week

I’m on fluvoxamine for MDD, Anxiety and OCD. This week I increased my dose to 100 mg. I am trying to figure out the best time of day to take the medication. When I was taking 50 mg I was taking it all in the morning to help with the insomnia. Now that I am on 100 mg I’m not sure if I should take the entire dose in the morning or to split the dose and take 50 mg in the morning and 50 mg at night. Yesterday I took 50 mg in the morning and 50 mg at night. I fell asleep fine but I woke up at 3 AM and could not get back to sleep. This morning I took all 100 mg in the morning. I am extremely nauseous and very tired, which is odd because I also am having sleeping. Does anyone have any advice? Thanks in advance. I think the medication is helping, but I really need to get past these side effects.

I'm George, building a mental health app called Claro.

Fluvoxamine is a different medication to be on. The drug interaction list alone puts it in its own management category. Titration, twice-daily dosing, and there's less community knowledge on it than there is for sertraline or fluoxetine. Managing it between appointments is genuinely more work.

I built Claro around appointment reports. You track what's happening week to week, the app turns that into a structured summary, and you walk into your next appointment with something concrete to show your psychiatrist.

I'm looking for founding users. Free while we build it, the core output is a week-by-week report you can bring to your appointment. People in the founding group have real input on what gets built, through actual conversations, and there's a psychologist in the group chat for questions as they come up.

Fluvoxamine users are underrepresented in what we've built so far. That's why I came here specifically.

Ten to fifteen people. DM me or comment. And a thousand thanks for permission to publish, I hope this doesn't disturb the community.

Hi. I know this is discussed in other threads and have read them. However just wanted to share and ask if anyone else experienced the following or similar:

My dr told me to start Fluvoxamine around 3 months ago, starting at 25mg and to taper up to 100mg at first. So I've been going this, upping in 12.5mg increases every couple of weeks. I stayed at 50mg for a while then went to 62.5mg for 10 days. Everything was fine, no major side effects.

Today I upped to 75mg (taken daily at 7am) and until 10am I felt confusion and disassociation. It then went away. It has thrown me a bit as I am worried this will continue and get worse. Booked a dr appointment for Monday next week. However just wanted to know any other similar experiences?

Thanks

hi, I just got prescribed this medication today and I’m just wondering has anyone had a loss of appetite with this medication?

Anyone here has GERD? I took fluvoxamine around a year and a half back in 2021 for my OCD, and I just got back on it after a family loss. The thing is, I didn't have GERD in 2021, but now that I do I'm getting pain, heartburn and a weird taste in my mouth as side effects of fluvoxamine 😭 my GERD is heavily influenced by my anxiety, and I hoped it would stay better under control with the fluvoxamine, but... maybe not?

If you have GERD, what has been your experience taking fluvoxamine?

Prior to starting Luvox I had a lot of anxiety. Stress would keep me awake almost every night. I developed physical ticks that would increase with stress.

I saw a psychiatrist on Brightside and was diagnosed with OCD and ADHD. I was prescribed Luvox.

I immediately cut out caffeine when I started it. I went from 300+ mg per day to 0. I dont think I had any side effects from my 50mg Luvox starting dose, but the first 7 days or so was miserable in terms of me being tired and nearly falling asleep constantly. Once the caffeine withdrawal wore off, I slept better than I ever have.

The problem is, my focus has gotten sooooo much worse. I always had focus issues but I could down coffee after coffee and keep my focus reigned in a bit. I'm an automation engineer and I do a lot of design work on a daily basis so I have to focus. I don't really want to be drinking all thar caffeine again though, because I do sleep a lot better. But the caffeine was magic for my focus. Now my thoughts are so scattered and crazy that Im surprised I managed to write this post.

Has anyone else had poor focus issues that developed as a direct result of taking Luvox? Or was the caffeine just masking ADHD symptoms that are worse that I ever knew?

Hi, I have been offered 30 mg mirtazapine to be add on to current 100 mg fluvoxamine + 300 mg bupropion..... But makes non sense to me

Any experience with this combo ?

Thanks

Im on my 10th week. I’ve recently switched to 100mg, a bit over a week ago.
Twice now, once at 50mg (a day or two after my last post), and once at 100mg, I’ve had a couple of days where it felt like I was seeing some change, I was feeling better, my worries were easier to put aside and were even less scary, and life just felt slightly easier. Then suddenly, I felt like I got back to normal, both times I was caught of guard because the change was so sudden and inexplicable.

Has anyone experienced this?

I feel like I'm at my wits end finding a medication that helps my anxiety and rumination without sexual side effects. I've been on Trintillex for a month now and buspar. Buspar helps but I need something more than just Buspar. Trintillex is giving me crazy anxiety, way worse than my baseline. I've tried quite a few SSRI's but all have sexual side effects and insomnia. How do you all like fluvoxamine? Does it help your anxiety? Do you have sexual side effects or insomnia? Would love to hear what doses everyone is on and whether it helps you.

I started 50mg Luvox in April and on about week 3-4 I lost my appetite all together. Even walking through the grocery store makes me feel full and ill. Just this week I was upped to 100mg because it wasn’t touching my OCD yet, and I still have no desire to eat or think about food at all. When I do eat, I can only manage to eat a bite or two. Does this ever get better?

Hey. A long time ago I was taking the max for OCD intrusive thoughts not sure how or why I got off of it but I remember really worked for my obsessive thoughts and such. Recently I found out which I pretty much suspected for a while but I didn't want to argue that I was misdiagnosed with bipolar 2 when I actually have depression. So I'm starting again I'm on 50 mg. The doctor that prescribed it said it could help with OCD AND depression. But I never heard of it for depression because it's labeled as an OCD drug primarily not depression and I don't know anyone that takes it for depression. Does anybody here that is on it for depression too find that it works or no?

Is it ok to drink while on fluvoxamine? I am taking 125mg of fluvoxamine at bedtime for my OCD, and have been for a few months. I have an event coming up and it would really be the only time I go out of my way to drink( I don’t drink at all otherwise). I am a fairly big guy, 5’11 195lbs. Lots of lean muscle mass but also a good amount of body fat (no visible abs or anything) what do you guys think?

Hi guys! Looking for advice. I was on sertraline before Luvox and was switched off because I was suddenly having very bad side effects (extremely tired and loss of appetite after 3 weeks).

I’ve been on Luvox for months now. Started on 25 mg and my psychiatrist recently upped me to 50. I have had 0 side effects until last Friday I noticed I was debilitatingly exhausted after work. Then on Monday I noticed I was just not hungry and haven’t been for the whole week.

Yesterday was a very bad mental health day for me. I am wondering if this has happened to anyone else?

I also take 20 mg of Adderall, but I don’t think she is the culprit.

Day 1 of taking fluvoxamine 25 mg. Is it normal to have SI? I was crying to my husband and my mum and told them about my SI. Is this normal or not normal?Should I go see my doctor?

Been on Luvox 50mg consistently since the beginning of September 2025. Recently entered a relationship and whenever we have sex I can't orgasm and it sucks. Is it normal to get these effects at a dose that is typically considered low?

I (25 F with OCD) have been on 50 mg Zoloft for 3 weeks and suffering from really bad depression and low energy. My provider is switching me from Zoloft to 25 mg of Fluvoxamine. I havent gone to pick it up yet because after being off of Zoloft for one day I actually had interest in getting out of bed. I have been doing so poorly that I’m really scared to go pick up this new prescription. She chose this one because it has the least incidence of sexual side effects which I had pretty bad with Zoloft so I’m anticipating that still being a thing on the new meds too. I just wonder if my OCD and anxiety is better to deal with than depression

Started fluvoxamine in February. 50mg first, then bumped to 150mg around week 6 after my psychiatrist checked in.

The first few weeks were a mess honestly. Nausea every morning for like 10 days straight. I remember eating plain crackers before taking it just to have something in my stomach. I almost stopped taking it twice, both times talked myself out of it because I'd already waited months to get the appointment.

The thing that shifted first wasn't the OCD stuff. It was this weird thing where I was in a work meeting and someone said something kind of passive aggressive and I noticed I wasn't replaying it for the next 3 hours. That sounds small but for me that was huge. The intrusive thoughts were still there but they weren't sticky in the same way.

By month 2 the OCD patterns were actually quieter. Not gone, but like... turned down. The volume knob moved maybe 30%. Which I know sounds underwhelming but if you live with it you know 30% is a lot.

Still dealing with afternoon fatigue and some nights I can't fall asleep even though I'm exhausted. Taking it in the morning helped a little with the sleep thing but not completely fixed.

My psychiatrist prescribed me 50mg of Fluvoxamine for the next two months or so: I have OCD and mild depression.

I’m 23 (F) and have a beautiful relationship. I’m really scared about the side effects regarding libido and sexual desire and it’s keeping me blocked on the decision to actually start the medicine.

I also can’t really understand what it means: for how I work, I’m interested in sex mainly when I’m cozy and alone with my partner and it’s very contextually dependent. Meaning that I mainly search for this kind of intimacy in terms of connecting with my bf.

But aside from viewing as a beautiful man and wanting to be with him when we’re alone I don’t really wake up and think about sex.

I just wanted some (positive) experiences and feedbacks maybe.