Back on meds. Feeling frustrated
I started Venlafaxine back in 2022 and went up to 150mg at my highest dose. It was amazing how I felt. Depression and anxiety basically disappeared. I enjoyed life and was excited for things. Couldn’t cry if I wanted to. I started to have some negative side effects late 2024. Couldn’t orgasm at times during sex. Gained 15% Of my body weight. Kind of started to feel like I was on auto pilot. Granted the lows weren’t as low as they once were before, but I wasn’t really experiencing the highs either, I felt flat.. decided to start tapering off of it and I took this very slow due to reading about how horrible coming off venlafaxine was (it is…) Took my last 37.5mg dose December 2025.
I had been doing okay without being on it until March. I started to notice. I was just grumpy and pissed off about everything. Wasn’t excited about much, just in a bad mood.
Had a doctors appointment first part of April (different doc this time) explained my past experience with venlafaxine. He decided to have me try Wellbutrin xl 150mg (the generic bupropion xl)Anxiety has been much worse. I thought I was gonna have a panic attack at times. One good thing was it motivated me to increase my exercising because I couldn’t hardly sit still. Lost 6lbs during the month of being on it.
Had my one month follow up appointment. Explained the good and the bad. The doctor took me exercising and being motivated to do more as a huge plus of the medicine and encourage me to not stop taking it just yet. We did talk about switching meds completely or adding something else to help. I started the generic of Prozac last week to add to my Wellbutrin. Started at 5mg and am now on 10mg Prozac and 150mg Wellbutrin.
I just don’t know what to do. I cried my eyes out the other day, which was the first time in years that I’ve cried. I feel nervous about everything. Depression has been really rough and I’m having suicidal ideation’s which I’ve had in the past, but went completely away when I was taking venlafaxine.
Been on 150mg bupropion for 5 weeks and 10mg Prozac for a week. Should I just keep riding this out. How do I know when to say this med isn’t for me?