I’ve had treatment resistant depression for a long time as well as Ssris worsening my depression or anxiety at times. I can’t medically prove it but having been in gabapentin for pain then anxiety related issues - I have noticed it helps my mood a bit. Not a lot because I don’t take much and my ssri is at a low dose. But I’ve posted here about the idea my doctor had of lamictal to help with the resistant depression treatment these past several years.

I am currently taking mirtazapine low dose (about 8.5mg) and 150 mg pregabalin.

Whenever i try to taper below 8.3mg, my symptoms come back with full venegance, my whole body is under electricity and i am in anxiety mode and my head pressure gets worse. It is torture, so i had to go back to 8.5mg after a few days multiple times.

I do microtapering and my steps are only about 0.1/0.2 mg. Stil i have so heavy withdrawl symptoms.

What else can i try? Does someone have any advice for me?

Ich leide seit Jahren Depressionen und Ketamine soll ja helfen können. Deshalb würde ich wissen wollen wo man es herkriegt. Mit freundlichen Grüßen

I (34F) have been on sertraline for 4 months for anxiety, which got worse in the postpartum period. I titrated up over the first weeks, 25mg → 50mg → 75mg, and eventually stabilized on 75mg, where things actually went pretty well — my anxiety was under control and I felt reasonably like myself.

About 4 weeks ago I increased to 100mg, mainly to see if there was more improvement to be had. Instead of feeling better, I now feel emotionally flat, I struggle to feel joy or excitement about things I normally enjoy. On top of that, my head feels busier than it did on 75mg, which is the opposite of what I expected. Sort of an internal restlessness rather than calm.

Since the increase didn't really add anything except side effects, I'm planning to discuss going back down to 75mg with my doctor. Has anyone experienced this, where a higher dose made you feel worse (flat + restless) and dropping back down helped? How long did it take before you noticed a difference after lowering?

Hey!

Quick overview- I have ADHD, OCD, PTSD, GAD & Depression. I started Wellbutrin ~3 months ago (150mg XL) for depression, and my dr is suggesting to add Lexapro for anxiety. I wanted to see if anyone has experienced Wellbutrin in the same way as me, and then added Lexapro and if it helped or not! Thank you!

Wellbutrin has helped me so so much in the depression realm since starting it, however I have had a couple issues heightened.

1. I have been EXTREMELY exhausted since being on it. I was always tired before starting it bc of other health problems, but welly b definitely makes me non stop pooped. I take it at night, fall asleep within minutes of trying (new to me lol), and can sleep for 12 hours but still wake up exhausted. I don’t feel *as* depressed, but I still lack motivation to do anything with is a lil depressing lol

2. I’ve always had anxiety, but it is THROUGH THE ROOF now. I’m not sure if it’s making my ptsd worse, but a lot of my death anxiety has skyrocketed. I’m definitely more anxious in general, but some things are especially ramped up.

All of that to ask-

-Did you start on Wellbutrin?
-Did you experience any of these symptoms?
-Did adding Lexapro help?
-Any weird side effects from Lexapro?
-Also anybody LESS tired after starting Lexapro?

Thank you so much for anyone’s time. I am extremely anxious about medications. It took a lot for me to even try Wellbutrin, so the thought of adding something else is also freaking me out but I’m willing to try anything atp 🫶

I just got prescribed my first antidepressant and picked it up from my pharmacy today. Feeling a little nervous/scared about taking it. I want to change but I'm also afraid of altering the way I think when I go about my life.

Just looking for a little advice from people who may have been in the same situation or know someone who has. Thanks for reading.

I started taking 10mg fluoxetine in 2019 for depression. I raised and lowered per my doctors guidance up until this point, never going above 20mg. Two weeks ago today, my doctor had me start taking 30mg. I have never gone this high on my dosage, but I wasn’t experiencing any crazy side effects until yesterday. Yesterday and today I have had insane brain fog. Forming a coherent thought has been really difficult, and I’ve just been unable to get out of bed. At work yesterday (waitressing) I couldn’t input food orders correctly that I have been able to do quickly and easily for a long time. Is this a side effect of a dosage change that other people have experienced?

Luvox 100mg and trazadone 50mg nightly. I also take a beta blocker in the morning + Gabapentin as needed. Am I at risk for serotonin syndrome?

I been taking Prozac 10 mgs for the past month and wellbutrin XL 150 mg for the past 3 months.

Wellbutrin worked fantastic for a month before it stopped working and so prozac was added. Ever since adding prozac I been experiencing elevated mood, unnatural positivity, energy, and euphoria. Sometimes I feel so energized I can’t stay still. Yesterday night I was only able to sleep after working out because I was way too wired.

Sometimes I have to skip a dose of prozac on the 3rd day because it feels to strong. I’m not against it since I don’t feel sad and I’m like a better version of myself but it feels weird and uncomfortable sometimes.

I’m starting to think I might have some underlying condition or maybe it’s a strong reaction?

Edit : it almost feels like I’m high. another thing I can describe is it feels similar to magic mushrooms but obviously with less intensity.

I got put on mirtazapine in January because I had an inflammatory episode and wasn't sleeping, nauseous with no appetite. 7.5mg to start up to 15mg, tried to cut it completely at some point in February unsuccessfully. About a month later after restarting had to go to the emergency room because my thoughts were all suicidal idealation, feeling like I was stuck in fight or flight all the time, and panic attacks, waking up after 4-6 hours with my heart racing, depersonalization and derealization, nausea and retching almost everyday, I was told I just have to tough it out and it will stop. After multiple gps did not take me off the mirtazapine or advise a taper I decided in June that I could not take it anymore, I've been off work even before tapering because my symptoms were unbearable. June 13 I started tapering 15, cut down to 11.5 for about 2 weeks and then 9.5 for about a week and now I'm a couple days on 7.5. I can feel my mind clearing, I was able to get in the car without having a panic attack and that's the first time I haven't felt absolutely flushed getting in a car. During this taper I've felt similar to the 15mg, nausea, retching, vomiting, not staying asleep, racing thoughts, I wake up and my mind will not stop filling with negative thoughts like I'll never be able to eat with friends, go back to work, keep up with household things, just all doom and gloom and feels like I'm absolutely buzzing and out of breath. I'm wondering if anyone else has had similar effects after months of 15mg and also how to manage the tapering, thanks to whoever takes the time to read this and/or respond <3

32F

TLDR: After seven years, I started cutting my 20mg paroxetine in half (to 10mg), how long can I expect the discontinuation symptoms (especially the constant dizziness/nausea) from this reduction in my dosage to last? My doctor said I shouldn't feel anything, but I definitely do.

I started taking 20mg of paroxetine (Paxil) in 2019 to treat major depression and various anxiety disorders (obsessive-compulsive, panic, generalized, complex post-traumatic stress, etc.) which had manifested into an acute depersonalization and derealization (the scariest thing I have ever experienced in my entire Life). It helped control my anxiety enough to come out of the dissociation, and I was also able to recover from a lifelong history of self-harm. I attribute it to my success with overcoming a couple phobias that I deal with and a marked reduction in my panic attacks. However, I didn't see much improvement with my trichotillomania or intrusive thoughts (which is okay).

After talking with my therapist and general doctor (who prescribed the medication), I am now cutting my scored 20mg pills in half (per my doctor's suggestion). My next prescription refill will be for 10mg pills. I have made great progress on the medication, and we are now hoping to continue to build on that progress with a smaller dosage (in conjunction with therapy and lifestyle changes). Ever since starting paroxetine, I have experienced hypotension, which I believe has also contributed to a chronic fatigue, and I have also experienced a low level mental dullness. I began the medication in crisis at the age of 25, the longterm goal was to eventually come off of it. So here we are (although I am going to hang out at the 10mg prescription for a very, very long time before even considering moving forward with a complete taper, if ever.

Today is the 5th day of the 50% decrease, and I am feeling it. (I have been feeling it since the 2nd day, with no improvement in symptoms from then to now.) I feel like I spun in circles really fast for a minute and then abruptly stopped—it's this constant state of vertigo, dizziness, feeling like the room is shifting whether my eyes are open or closed, I am so nauseous. My question is, can I expect this to worsen, or am I probably in the thick of it now? How long can I expect to have to ride this out without relief? Other, milder symptoms so far have been vivid dreams/nightmares, the occasional tingly feeling in my head (I guess these are the notorious brain zaps), insomnia (as of last night), and brain fog. It kind of reminds me of how I felt adjusting TO the medication in the beginning, honestly (except that came with debilitating fatigue, not insomnia).

Any home remedies or things that helped you? My best friend recommended cold showers and to drink lots of water! But I am open to other activities and remedies as well!

Thank you. ♡

Anyone notice that their heart rate is lower since taking the meds? I haven’t seen 60s as my RHR in a long time.

im taking liquid 10mg prozac for anxiety but im feeling terrible?!

im very nauseous, cant sleep and i feel like im almost high on adrenaline but confused at the same time? i am also still anxious and zoning out very often. im also questioning myself horrible things, obviously ive never hurt anyone and never will! but im really scared why im having these thoughts, ive never thought this way.

its been a few days since i started but i am genuinely scared to sleep. because last night i turned off the lights and i saw everything almost like breathing? also closing my eyes is terrifying, its like my brain is forcing me to try and look through my closed eyelids, causing me to have a small panic for some reason.

my stomach also hurts but i have other stomach problems im sorting out. because i have to get a endoscopy and im absolutely terrified to my core. i have to eat gluten for 6 weeks (i have a gluten intolerance) to test for celiac and im DYING. anyway..

i hope someone can help me im freaking out

I am on day 4 of 25mg of Sertraline which I take every morning at 7am with toast, coffee and glass of water. This is my first ever go of antidepressants snd I am struggling. I have raised it with my GP Surgery who will have someone call me but I need a bit of support. I would describe myself as highly sensitive and prone to chronic low mood, negative outlook, depressive episode bouts of crying.

Day 1Nausea and GI upset was terrible on day one but no major issues other than a touch of insomnia that night which I have never experienced before.

Day 2 felt slightly out of it but mostly due to sleep deprivation. Looser bowels maybe but nothing of note. Got the most sleep I have had in a long time that night.

Day 3. Awful. Severe anxiety, feeling like I’m on MDMA but not in a good way. Jittery, paranoid, heart pounding, disassociated, tired but wired, barely slept at all last night. Keep panicking randomly. Numbness/tingling in extremities. This all developed throughout the course of the day. Felt the urge to cry but couldn’t. This was I unnerving as I cry a lot.

Day 4. Today I feel slightly better, a bit out of it, tired, heart racing, anxious. Am able to work from home.

Hey everyone, I was wondering which antidepressant had the least risk of gaining weight.

hi evry1, ive been on lexapro 10mg for a few weeks now (i think maybe 2-3 weeks), and im still feeling depressed and my anxiety feels worse then when i started. i was told it takes four weeks for it to start working properly but my sister who is also on lexapro told me she started to feel better a week or two after starting. is this because our bodies are reacting different? before i started lexapro i was recently on fluoxetine and that didn't work either. how long should I wait before asking to up the dosage/ try a different kindof meds?

Also, why do i feel more horny??? i feel like when i get myself off it just comes back and i want to do it again but i feel so exhausted lmfao, is this a problem with anyone else because i was told that antidepressants make ur hormones calm down or something.

I have been in Effexor for about 3 years after hitting my head and being diagnosed with a TBI. I am someone who has never been able to take SSRIs because they make me suicidal (many many years ago I tried everything under the sun for my CPTSD and panic attacks). After many years I got to a great point and then hit my head. This TBI caused mood swings that we tried to wait out and inevitably my neurologist wanted to watch me closely on Effexor.

It actually did help for quite some time but then my concussion and TBI care switched to my PCP after insurance changes. Around 1.5-2 years in I started getting that suicidal ideation and asked to come off, instead she added medications, began treating me for ADHD with Adderall, and even upped my dose of Effexor. I was on 75mg for the last 1.5 years and notice it’s just getting worse. After asking my doctor to ween me off she refused, which all in all became a disaster until I found a new PCP.

This new doctor took me from 75mg to 37.5mg about 3-4 days ago and I’m not good. I expressed my concerns about withdraw and asked to taper slower but she said I should be fine… well I’m not fine and need to know if anyone experienced something similar and what they did to get through.

I can’t stop crying and I get irate about the smallest things. I am struggling more than ever with suicidal thoughts. I don’t actually want to die but I feel like I can’t live. It’s like I’m fighting my own brain. But I also don’t feel comfortable going to get help because 1. So many of my friends said hospitals made this worse and 2. Because of my career this could cause issues long-term. I am in a field with high vicarious trauma which doesn’t help and I’m trying to pull back at work until this is under control. I however, don’t want to ruin my career over talking to the wrong person.

Now, I feel like in order to stay alive I have to run away. I haven’t been able to respond to calls or texts from my husband, family, etc. I feel numbed out when I separate from everyone and everything but this keeps the suicidal thoughts, emotional breakdowns, crying, agitation, and panicking at bay.

I also am sooooo nauseas with horrible brain zaps.

I am powering through but I need to know if this is something that is normal and I should expect will go away. I can get through it if I know what to expect and about how long to expect it. I’m trying to fight my brain with logic and if I know this will pass then I can overcome it.

I used to be anti anti psychotics for a long long time. Now i am on one that seems to be helping? Downsides are no sex drive and food cravings, and some akathesia. But i am wondering if it can help me stay out of the hospital. Im on a shot form so im sort of tied into this. Im trying to look at the bright side, all the ways this is helping stabilize my life. Plz tell me that this really is helping, that meds despite side effects can do what theyre supposed to. Thanks

Currently been on 10 mg citalopram (first time SSRI user) for 3 weeks (am a male). I think my libido has definitely dropped, but so far it’s not too bad, I still get orgasms but a bit more difficult and not that horny in general. But if it stayed like this I’d still be okay as I had had a fairly high drive before.

But after reading many posts I don’t know by when to expect the worst so that I can make a decision whether to keep going with it (obviously after talking to my psychiatrist)?

Thank you.