u/Altruistic-Arm9207

PCOS + Letrozole + Ovidrel: Back Pain After Ovulation?

Hi!

I’m wondering if anyone who has taken letrozole and Ovidrel has experienced back pain on the same side as their dominant follicle?

At 1 DPO, the left side I ovulated from felt very calm/quiet (aside from my right ovary, which has a “string of pearls” appearance and seems more reactive from the trigger shot + PCOS/PMOS), but now at 2 DPO I’ve been waking up during the early hours with a really achy lower back pain that wraps around into my left hip.

Changing positions doesn’t seem to help much.
I’m honestly a bit nervous because last cycle I didn’t ovulate and ended up with debilitating back pain
.. it got so bad that I could barely stand long enough to cook, and even sitting upright to use the bathroom was difficult 😵‍💫. I ended up having an anovulatory bleed that month, and the pain cleared up within a couple of days once the bleeding started.

That anovulatory cycle was my first cycle on 5mg letrozole without a trigger shot. This current cycle is the one where I finally responded after stair-stepping from 5mg to 7.5mg due to no follicle growth earlier in the cycle, and it’s also my first ever trigger shot cycle.

I’m really hoping this cycle stays more manageable and that actually ovulating might make things a bit better compared to an anovulatory cycle/bleed. Hopefully it doesn’t turn into a repeat of last month!

reddit.com
u/Altruistic-Arm9207 — 7 days ago
▲ 1 r/PCOS

Medicated cycle letrozole + trigger shot 2dpo back pain

Hi!

I’m wondering if anyone who has taken letrozole and Ovidrel has experienced back pain on the same side as their dominant follicle?

At 1 DPO, the left side I ovulated from felt very calm/quiet (aside from my right ovary, which has a “string of pearls” appearance and seems more reactive from the trigger shot + PCOS/PMOS), but now at 2 DPO I’ve been waking up during the early hours with a really achy lower back pain that wraps around into my left hip. Changing positions doesn’t seem to help much and I have no pain from my right side anymore.

I’m honestly a bit nervous because last cycle I didn’t ovulate and ended up with debilitating back pain. It got so bad that I could barely stand long enough to cook, and even sitting upright to use the bathroom was difficult 😵‍💫. I ended up having an anovulatory bleed that month, and the pain cleared up within a couple of days once the bleeding started.

That anovulatory cycle was my first cycle on 5mg letrozole without a trigger shot. This current cycle is the one where I finally responded after stair-stepping from 5mg to 7.5mg due to no follicle growth earlier in the cycle, and it’s also my first ever trigger shot cycle.

I’m really hoping this cycle stays more manageable and that actually ovulating might make things a bit better compared to an anovulatory cycle/bleed. Hopefully it doesn’t turn into a repeat of last month!

reddit.com
u/Altruistic-Arm9207 — 7 days ago

Looking for success stories: how many tries with TI, letrozole and trigger shot did it take for you to conceive?

Hi guys!

This is my second cycle doing TI with letrozole, and this time I also used a trigger shot. During my first cycle on 5mg letrozole, I grew a dominant follicle but unfortunately didn’t ovulate.

This cycle has been a bit of a rollercoaster. I had to stair-step up to 7.5mg because I didn’t respond to 5mg earlier in the cycle. On Thursday, five days after my last pill, I had a scan and they found one 17mm follicle on my left ovary. I was told to take my trigger shot at 8pm that evening.

Ovulation seems really promising this time, which is exciting because I no longer ovulate naturally and haven’t had a natural period in over 2–3 years. It’s now Friday, so ovulation should hopefully have happened today. I think I may have felt a weird sensation around 2am that could’ve been the follicle rupturing, but who knows 😂 Either way, I’m just happy to finally have a better chance this cycle.
I know the chances each ovulatory cycle are still relatively low, around 15–20%, so I’d love to hear from others.. how many cycles or attempts did it take for you to conceive?

I’m really hoping this journey won’t be too long 🥺 Fertility treatment can feel so emotionally and financially exhausting.

reddit.com
u/Altruistic-Arm9207 — 9 days ago
▲ 4 r/FirstTimeTTC+1 crossposts

Hi, I’m on my second TTC cycle on Letrozole. I’m CD12 today and had my first scan for this cycle. I’ve been taking 5mg Letrozole this cycle (CD3–7) and I’ll be planning a trigger shot this time.

Last cycle (my first medicated cycle), I was also on 5mg Letrozole and I grew one 15mm follicle by CD13. I was advised TI from CD14–18. Unfortunately, I don’t think I ovulated :( It may have stalled or needed a push with a trigger shot. But at least it showed I can respond to Letrozole initially.

Today’s scan showed I haven’t selected a dominant follicle yet, and the nurse said there’s a “ring of pearls” on both ovaries (typical for PCOS). I felt a bit devastated because I responded earlier last cycle. I know it’s still early and I could still select a follicle in the next few days. I have another scan on CD16 to see if there’s any progress. I’m just really hoping I’m a late responder this cycle. Medicated cycles really put my body out of whack and I feel sore most of the time 😵‍💫

I’d love to hear some of your stories… what CD did you notice your body selected a dominant follicle on Letrozole?

I’m just hoping to connect with someone who relates to my situation. TTC can feel so isolating sometimes :(

reddit.com
u/Altruistic-Arm9207 — 24 days ago

Hi, I’m on my second TTC cycle on Letrozole. I’m CD12 today and had my first scan for this cycle. I’ve been taking 5mg Letrozole this cycle (CD3–7) and I’ll be planning a trigger shot this time.

Last cycle (my first medicated cycle), I was also on 5mg Letrozole and I grew one 15mm follicle by CD13. I was advised TI from CD14–18. Unfortunately, I don’t think I ovulated :( It may have stalled or needed a push with a trigger shot. But at least it showed I can respond to Letrozole initially.

Today’s scan showed I haven’t selected a dominant follicle yet, and the nurse said there’s a “ring of pearls” on both ovaries (typical for PCOS). I felt a bit devastated because I responded earlier last cycle. I know it’s still early and I could still select a follicle in the next few days. I have another scan on CD16 to see if there’s any progress. I’m just really hoping I’m a late responder this cycle. Medicated cycles really put my body out of whack and I feel sore most of the time 😵‍💫

I’d love to hear some of your stories… what CD did you notice your body selected a dominant follicle on Letrozole?

I’m just hoping to connect with someone who relates to my situation. TTC can feel so isolating sometimes :(

reddit.com
u/Altruistic-Arm9207 — 24 days ago