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u/ArkaneelRoy — 3 days ago

AutoDock Vina results with HO-2-IN-1 with COX-2

Hi everyone,

I'm an 18-year-old student from India who's recently become fascinated by computational biology. My background is stronger in mathematics than biology, and I'm very new to molecular docking, protein structures, and computational drug discovery.

I've started experimenting with AutoDock Vina using publicly available protein structures as a way to learn. I know enough to realize that I don't know enough, so I'm here to understand how to interpret my results correctly rather than make claims.

As one example, I docked Heme Oxygenase-2-IN-1 against COX-2 (PDB: 5IKR) and got a best docking score of -8.385 kcal/mol. Since this surprised me, I'd like to understand whether this could be due to blind docking, the scoring function, protein structure choice, or something else.

I'd really appreciate any corrections, reading recommendations, or advice on what I should learn next.

u/ArkaneelRoy — 4 days ago
▲ 3 r/IISc

Research in IISC

I aspire to do my research on interdisciplinary fields like let's say I have a major but still I want to contribute in other domains too I heard IISERs provide the best environment for this but there is little information about this for IISC should I join IISC if I have the marks in IAT to join it based on my interests .🥹 And how about the frequency of internships for maths and physics majors ?

reddit.com
u/ArkaneelRoy — 8 days ago

Streetwear Startup from India

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Working on my first streetwear release: It's a oversized fit and I'm using DTF over 180gsm pure Cotton

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I intentionally kept the front blank except for subtle branding and placed the main graphic on the back. My goal was to make it wearable for everyday use while keeping the storytelling/design focus on the back.

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Would appreciate honest feedback on:

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1.Overall design

2.Whether the blank front works

3.Graphic placement and sizing

4.Whether you'd actually wear something like this

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And please suggest me the modifications that I can make

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u/ArkaneelRoy — 18 days ago

Query Regarding Maulana Azad College (Statistics)

Guys I got MAC (Bsc in Statistics) allotted for the first round of WBCAP counselling. How is the department of statistics there ? And can you please tell me about Maulana Azad College the academics and everything.

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u/ArkaneelRoy — 25 days ago