Has anyone experienced an improvement in their migraine attacks after starting metformin?
I used to have migraines at least once a week, but after starting metformin a month ago, I haven’t had a single episode.
Estou na minha terceira semana de Contrave, tomando uma dose de 90 mg de bupropiona + 8 mg de naltrexona duas vezes ao dia. Pessoalmente, não tive nenhum efeito colateral grave, apenas sonolência e náusea leve a moderada. Achei que, como meus efeitos colaterais eram relativamente leves, eles provavelmente desapareceriam na terceira semana, mas ainda estou sentindo sonolência e náusea.
Para aqueles que já estão usando há mais de um mês: os efeitos colaterais realmente desaparecem depois de um tempo? Alguém ainda os sente mesmo depois de um mês?
Estou preocupada que minha náusea possa ser psicológica, porque suspeito que eu possa ter emetofobia.
Hi! I don’t have diabetes or prediabetes, I only have insulin resistance. But I was wondering if you think it would be worth buying a blood glucose monitor to track my glucose levels throughout the day/weeks, or if you think this isn’t really useful or interesting in my situation?
Just to add: I’m already taking metformin daily.
I’ve heard some professionals say that intermittent fasting is more effective for weight loss, while others say that what really matters is the calorie deficit you create, regardless of how many meals you eat or how long you go without eating.
Both sides seem to have valid arguments, but I’d really like to hear from people who have actually tried both.
Have you ever done a calorie deficit and/or intermittent fasting? What worked better for your body? What gave you faster results? What made you lose more weight?
And yes, I know it’s a combination of factors. I know physical activity matters, strength training matters, drinking plenty of water matters, reducing carbohydrates matters, etc. I already know all of that. 😅 I’m specifically asking about fasting vs. calorie deficit and what actually worked better for you.
What was your experience?
Oi, pessoal! Estou com uma dúvida e queria saber se alguém que tenha alguma experiência, conhecimento, trabalha com Registro Civil ou Direito de Família pode me ajudar.
Vou me casar e gostaria de retirar um dos meus sobrenomes para acrescentar o sobrenome do meu futuro marido.
Pesquisando, encontrei no Código de Normas do TJPE uma regra dizendo que, no casamento, é possível acrescentar o sobrenome do outro, mas que é vedada a supressão, salvo de agnome quando houver o acréscimo. Exatamente o que me foi informado pelo cartório.
Ao mesmo tempo, vi que o Código Nacional de Normas do CNJ, no art. 515-L, §1º, prevê que a inclusão do sobrenome do outro cônjuge permite a supressão de sobrenomes originários, desde que permaneça pelo menos um sobrenome de uma das linhas de ascendência.
Então fiquei com uma dúvida: o cartório em Pernambuco pode negar a retirada de um sobrenome no momento do casamento com base nessa norma do TJPE, mesmo existindo essa previsão no Código Nacional do CNJ?
Hi everyone! First of all, I’m sorry for my English. I’m not fluent, so some of my translations may be incorrect.
I’d like to know how long it took for you to actually start seeing an effect on the scale. I have insulin resistance and a lot of difficulty losing weight. I take metformin for insulin resistance, and I started taking Contrave (compounded at a pharmacy / the “budget version”) 15 days ago.
It affected my appetite from the very first days, and I started eating less, but I still have a strong craving for sweets, even though it’s controlled. I don’t have binge-eating episodes, I just have a strong desire for sweets because of my insulin resistance.
I’d like to know how long it took for the medication to actually start making a difference on the scale.
I’m a 27-year-old woman, currently weighing 78 kg, and I plan to reach 65 kg by November, which is when I’m getting married. ❤️
My experience with weight loss, PCOS and insulin resistance
Hi everyone! First of all, I’m sorry for my English. I’m not fluent, so some of my translations may be incorrect.
I wanted to share my experience and ask for some advice from people who may have gone through something similar.
Over the course of about 4 years, I progressively gained around 23 kg without any obvious explanation. I had always maintained pretty much the same lifestyle and diet. Then, from May to December 2025, I gained around 8 kg, which really scared me because it happened so quickly that I lost the ability to fit into many of my clothes.
At the beginning of this year, I started changing my diet and exercising. I was walking and doing strength training 5 times a week. I did this consistently for exactly 3 months, but I couldn’t lose even 1 kg.
So I saw an endocrinologist. After blood tests and an evaluation, I was diagnosed with PCOS and insulin resistance. I also developed dark patches of skin on different parts of my body.
I made further changes to my diet, significantly reduced my sugar and overall carbohydrate intake, and currently do strength training 3 times a week. I take 1,000 mg of metformin per day (I’ve been taking it for about a month), and I’m also taking Contrave to help control my appetite, as well as vitamin supplements because some of my levels were low.
Even though I’m doing what I’m supposed to, I still feel completely stuck. I’m not losing weight, I don’t see any noticeable changes in my body, and it feels exactly like before I discovered what was going on.
If I go off my plan for even one meal, I sometimes see 1–2 kg more on the scale afterward.
I’d really like to hear about your experiences: How long did it take for your medications to start making a noticeable difference in your weight loss?
I know it’s still early to expect major results, but it’s frustrating not to see even 1 kg less after months of trying.
Did anything in particular help you finally break through a plateau or “unstick” your weight loss?
I need to lose around 13 kg by November because I’m getting married, so I’m feeling quite anxious about the timeline.
I also have questions about my metformin dose. I’ve read that some people with insulin resistance may need at least 1,500 mg per day, but I don’t know whether 1,000 mg is enough in my case.
There are so many questions and doubts, and I’d really appreciate hearing from people who have been through something similar. ❤️