
Does a Full 4oz of water work BETTER? (re: "middle-of-the-night" strategy)
Hey y'all,
I’ve been doing the "middle of the night" strategy, where I take the Oral Wegovy tablet around 2am, and then go back to sleep for 2+ hours to maximize absorption.
I was looking at the attached Reddit-famous clinical chart and noticed something that seems to contradict the standard "sip of water" advice if you're fasting long-term:
According to the data for a 120-minute fast:
Taking the pill with 4oz = 120mL of water actually resulted in a higher drug concentration in the blood.
(Taking it with 50mL = 1.5oz at that same 120-minute mark was less effective.)
It looks like the "tiny sip" rule is crucial if you only wait 30 minutes -- but if you're waiting 2 full hours, more water actually helps it absorb better.
My question for the group is:
For those of you who take the tablet 2+ hours before breakfast, how much water are you using?
It seems like the 120mL/120min combo is the "gold standard" for effectiveness based on this study. Curious to hear your experiences!