u/DR_I

Just started Wegovy this week. I seem to be in the lucky camp of having it take effect immediately. I've realized great appetite suppression this week. I still feel hunger, but I can eat smaller portions more frequently to satisfy the hunger. I have no desire for ultra greasy food, or even sweets. Not that they repulse me or anything, I can't explain it. My brain knows I love these things, but at the same time it also just doesn't care to eat them right now?

Anyways, as I said. Started this week. Last week technically, dose #2 of 0.25mg is tomorrow. I'll almost certain continue another month at 0.25mg since I'm taking to it well. The issue is, I am going on a vacation in August for two weeks. I don't want to change doses just before vacation. So, if after the second month at 0.25mg I still feel okay, continuing means I need to continue at that dose for another 2 months.

I guess I'm just asking if anybody has had similar timing constraints when considering dosage changes, and what your experience was.

Surely not just an overweight person thing. But I always find myself making excuses as to why an activity I had planned doesn't make sense (I'm tired, I exercised yesterday, I have less time than I had planned for, it's too hot/cold/rainy/whatever, etc.), or why I should spend a small window of free time relaxing rather than being active in some way. Not to say you need to be 100% go go go all the time, but those small changes in activity do add up. And even more so, the mental strength and discipline you build by choosing the inconvenient over the convenient are what eventually snowball into broader habit changes that can help sustain the new you.

M/40/6'3"/~245lbs

I've pretty much always been obese, with the highest weight I can remember being 330ish. When I moved out on my own in my late 20s, I got serious about my health and dropped from ~300ish to ~250ish. Over the last 4-5 years I've mostly sat around 235-240.

Lately though, between marriage, kids, more takeout, and just general life, I have just been unable to drop further weight. And in some cases the trend has been going the wrong direction. I got down to 224 around Oct 2024 after some bad cholesterol bloodwork scared me into tightening things up, but I didn't maintain it long. More recently I was back up around 247. Some of that is surely water weight from getting back into lifting/running consistently, but appetite has absolutely been harder to manage too.

Started Wegovy 0.25mg yesterday at 4:40pm. I honestly expected placebo effect, but even that night something felt different. Hunger still exists, but the constant drive to keep eating past what's reasonable just...isn't there right now.

That's the weird part mentally for me. I've spent years trying not to eat at certain times because once I started eating, it was easy to overshoot. Not binge eating, just a consistent surplus from portions/snacking/grazing.

Tonight around 7pm I felt hungry. I've had fewer calories today, an hour long lifting session, and a 5k run. Usually I'd maybe have a piece of fruit, but then would follow up with a large bowl of cereal. But tonight, I had an apple, felt satisfied, and that was it. That's honestly kind of wild for me.

I know it's only been ~1.5 days, and maybe some of this is placebo/novelty, but the reduction in food noise feels very real already. I am super paranoid about the effect wearing off, or that it's just me in one of my "locking in" modes and will wear off. Also worried about dosage increases and side effects, etc. But anyway, really hopeful for this one.