u/Emlip95

CGRP Inhibitors vastly improved my skin

Hi all, 30f type 2 rosacea and hormonal acne

I have a very complex medical background including small fiber neuropathy, pots, gastroparesis, chronic vestibular migraine and suspected hypermobile Ehlers Danlos syndrome.

Recently I got the courage to try a CGRP inhibitor Qulipta. Not only did this dramatically improve my neurologic symptoms (which are disabling), my skin has changed almost overnight.

The deeper I dig the more things I learn about what CGRP does in the body.. one being managing mast cells in the skin and decreasing sebum production.

I’m not suggesting anyone go to their derm and ask for this prescription, you absolutely will not be able to get your hands on it for anything besides migraine currently but rather drop some incredibly interesting info here for others to learn about as well.

Giving you all my best!

reddit.com
u/Emlip95 — 25 days ago

Left eye only

30f sfn, pots, gp, heds, cvm

Hi all, I’m writing here in hopes to have a discussion regarding one eye chronically acting up. I have had dry eye for a decade but it has never given me issues and I’ve never needed to treat until now. My health is complex however.

October 2025 I had a bacterial conjunctivitis caught from an animal and I used an erythromycin ointment in the eye for a week and all was well afterwards.

Fast forward a month and the redness and inflammation comes back, I call the eye doc and he sees me and says it’s not infected just inflamed and tells me to use systane drops multiple times a day. I am lax with this and the left eye flares up monthly and I beat it back with eye drops.

I finally made the plunge and got some gel drops because it just keeps coming back but last night it went from fine to absolutely Inflamed in maybe a 6 hour period. I saw it starting to act up and I added my drops and it progressively got worse. This morning I went to the eye doc who said once again it’s inflammation but doesn’t know from what.

Just wondering if others have any experience with a unilateral dry eye or if I should be concerned regarding neurologic involvement? I do have sfn and autonomic dysfunction which can cause the dry eye in general but the one sided nature of it concerns me.

u/Emlip95 — 27 days ago