u/Frequent_Finger_1166

Hello! I started bupropion (150XL) again a little over a week ago. The first few days were a bit rough as I was extremely exhausted and slept a lot most of those days. I don’t notice a difference until Sunday (2 days ago) - My mood was a bit better and had a bit more energy. And yesterday was amazing. I was in such a good mood and had no issues (energy wise) getting things done. Weirdly last night I had bad insomnia that not even zzzquil helped. I probably got about 3ish hours of sleep last night.

I went to the mall today (ive been to this mall plenty times since I was a baby)… I ended up getting LOST at this mall and had absolutely no sense of direction and kept getting confused. It was so bizarre. I’ve gone through nights of insomnia before but never experienced what I experienced today…

I cant remember if I struggled with Insomnia or memory loss the last time I was on bupropion (10yrs ago). It was a bit strange considering I was 100% fine yesterday. Could it be the sleep deprivation + bupropion combo? Does a lack of sleep affect how the medication works?

My motivation to do ANYTHING is absolutely shot now. I’ve been on wilshire before and never experienced such a drastic hit to my mental health before. Idk how to cope rn. For reference, I am on 10mg 4x daily. These days I’ve been taking twice my dose just to get by and it still isn’t helping at all. Never had this issue on zenzedi but had to take Wilshire bc my pharmacy couldn’t fill brand. First few weeks on Wilshire was absolute hell. Extreme insomnia and horrible side effects during the day. Felt cracked out and chewed the inside of my cheeks bad. But after those few weeks I am now left feeling dull and numb with zero motivation and zero effect. I don’t understand why the first few weeks on generic seemed a bit much, and now it’s like it’s not even working at all? Not even doubling my dose has any effect weirdly. I am so confused. I am now at a point where I just want to give up which is dangerous for me because once I hit that low, it takes MONTHS to a YEAR to recover from a bad month or two…