u/Glittering_Candy9260

I’m honestly getting desperate with my spiro experience and wondering if anyone went through something similar and eventually got good results.

I have AGA. I started in January: 50mg for 6 weeks, 75mg for 2 months, and 100mg since early May. I had restarted minoxidil a few months before spiro and was actually getting nice regrowth by March/April.

Then everything went downhill. I started shedding again, especially around my hairline, temples and sides, and basically lost all my minoxidil gains. My hair has thinned instead of improving, and my density is now worse than my starting baseline.

My derm wants me to stay on 100mg until March 2027, but it’s really hard to trust the process. I keep wondering if spiro triggered a prolonged TE, but I can barely find stories of people who shed for 6+ months, got worse than baseline, and then eventually had good regrowth.

Has anyone actually experienced this and recovered? This is seriously affecting my mental health and I’m starting to lose hope. 😞

I’m honestly getting desperate with my spiro experience and wondering if anyone went through something similar and eventually got good results.

I have AGA. started in January: 50mg for 6 weeks, 75mg for 2 months, and 100mg since early May. I had restarted minoxidil a few months before spiro and was actually getting nice regrowth by March/April.

Then everything went downhill. I started shedding again, especially around my hairline, temples and sides, and basically lost all my minoxidil gains. My hair has thinned instead of improving, and my density is now worse than my starting baseline.

My derm wants me to stay on 100mg until March 2027, but it’s really hard to trust the process. I keep wondering if spiro triggered a prolonged TE, but I can barely find stories of people who shed for 6+ months, got worse than baseline, and then eventually had good regrowth.

Has anyone actually experienced this and recovered? This is seriously affecting my mental health and I’m starting to lose hope. 😞

I have AGA and had been using minoxidil with encouraging results and noticeable regrowth. I started spironolactone at 50 mg, increased to 75 mg after about 6 weeks, and eventually to 100 mg. As I increased the dose, my hair began getting significantly worse. I’ve lost a lot of the regrowth I had gained, especially around my temples and frontal hairline, and my overall density has dropped.

Another strange change is my hair texture. In areas that seem particularly hormonally sensitive, the hairs have become thicker, coarser and wiry, which is very different from how they were before.

What’s confusing me is that my middle part is still relatively narrow despite the noticeable loss of density, while my temples and frontal hairline have deteriorated much more.

Spironolactone is supposed to help AGA, yet my experience has been the opposite. I’m wondering if the strong change in androgen activity could have disrupted the hormonal signaling my follicles were responding to with minoxidil.

I’ve also experienced breast enlargement and menstrual changes since starting it, which makes me wonder if the hormonal shift is affecting my hair as well.

Has anyone else experienced worsening hair or major texture changes on spironolactone, particularly after increasing the dose? Did reducing the dose or stopping it eventually allow your hair to recover? I’m terrified of making another change and triggering an even bigger shed.

I have AGA and had been using minoxidil with encouraging results and noticeable regrowth. I started spironolactone at 50 mg, increased to 75 mg after about 6 weeks, and eventually to 100 mg. As I increased the dose, my hair began getting significantly worse. I’ve lost a lot of the regrowth I had gained, especially around my temples and frontal hairline, and my overall density has dropped.

Another strange change is my hair texture. In areas that seem particularly hormonally sensitive, the hairs have become thicker, coarser and wiry, which is very different from how they were before.

What’s confusing me is that my middle part is still relatively narrow despite the noticeable loss of density, while my temples and frontal hairline have deteriorated much more.

Spironolactone is supposed to help AGA, yet my experience has been the opposite. I’m wondering if the strong change in androgen activity could have disrupted the hormonal signaling my follicles were responding to with minoxidil.

I’ve also experienced breast enlargement and menstrual changes since starting it, which makes me wonder if the hormonal shift is affecting my hair as well.

Has anyone else experienced worsening hair or major texture changes on spironolactone, particularly after increasing the dose? Did reducing the dose or stopping it eventually allow your hair to recover? I’m terrified of making another change and triggering an even bigger shed.

Has anyone else noticed a texture change with Menarini Tretinoin 0.025%?

I just received two new tubes, and they're completely different from what I've always used. My previous tubes were a bit runny, almost gel-like, with a slight yellow tint. These new ones are thick, creamy, and much whiter.

I also noticed the box looks a little different and has less information printed on it.

Now I'm wondering if Menarini changed the formulation, if the tubes were affected by heat during shipping, or if I should be worried about them being fake.

Has anyone bought Menarini 0.025% recently? Did you notice any changes in the texture or packaging?

For those who have been on spironolactone, when did your shedding stop, and when did you start noticing significant regrowth?

I'm getting seriously concerned because I've been on spironolactone for 6 months. I started at 50 mg, increased to 75 mg, and have been on 100 mg for the past 2 months. While my shedding has decreased a little, it's still happening, and my hairline hasn't improved at all. In fact, I feel like I've lost the small amount of regrowth I had achieved with topical minoxidil before starting spironolactone.

It's becoming really frustrating, and I'm starting to wonder if spironolactone is the right treatment for me. I don't have PCOS or any other hormonal condition—just androgenetic alopecia (AGA).

I'd really appreciate hearing about your experiences. Did anyone have a slow response and eventually see good results, or did you realize spironolactone just wasn't working for you? I'm feeling really worried at this point.