15+ years on omeprazole: anyone successfully moved away from daily use?
I’m 43 and have been taking omeprazole for more than 15 years. When I was younger I had episodes of acute esophagitis and was taking 20 mg or more. Over the years this was reduced to 10 mg/day, but I’ve found it very difficult to stop completely: when I try, reflux/gastric discomfort tends to return and I eventually restart it.
My diet is pretty normal — regular meals, no particular restrictions or major food excesses, occasional alcohol.
I recently had a new gastroscopy. It showed a small uncomplicated cardio-tuberositary malposition (mild anatomical predisposition to reflux) and non-ulcerative gastritis, but importantly no current esophagitis or visible reflux damage. H. pylori was negative. They also found benign fundic gland polyps, considered likely related to long-term PPI use.
My gastroenterologist now recommends lifestyle measures and omeprazole on demand rather than continuously.
I’m curious about people with a similar history: 10–20+ years of daily PPIs, particularly after previous esophagitis. Did you manage to stop or switch to on-demand use? Did you taper? How bad and how long was the rebound acid hypersecretion?
My biggest question is how to distinguish temporary rebound after 15+ years of omeprazole from the underlying reflux actually returning.