u/Impressive-Fall-7015

I am taking part in a 5-meo DMT clinical trial
▲ 9 r/bufo+1 crossposts

I am taking part in a 5-meo DMT clinical trial

Needless to say, I'm kinda terrified and I wasn't sure where to ask this question.

I don't want to say too much about the clinical trial or the company conducting it because that's their business, but the trial is exploring the potential of this chemical to treat treatment-resistant depression. I did watch a documentary on YouTube about DMT and it looks like there's a difference between 5-meo DMT and n-n DMT.

It was this one if you're interested - https://www.youtube.com/watch?v=hhjhU5MXZOo

I'd like to ask if anyone familiar with this thing? And what exactly should I expect when it happens? I hear talk about elves and spiritual beings but also demons and lord knows what else. Should I be scared?

Any help would be greatly appreciated. I'm feeling quite nervous.

u/Impressive-Fall-7015 — 5 days ago

3 months on Hydroquinone (John Plunkett's Superfade Cream)

Hello everyone,

This post is intended as a review of my experience with hydroquinone 2% for dark spots, for anyone interested in trying it themselves.

- I am 37 and male. My melanin distribution is a Fitzpatrick 2 or 3, where I can tan but mostly burn.

- I have been using sunscreen daily since I turned 30, but the last few years I have noticed some sun spots developing on my cheeks. This may be due to not re-applying sunscreen throughout the day.

- I used John Plunkett's Superfade Cream ($30 for 40mL) twice daily for exactly 3 months. This is an over the counter option we have here in Australia, not a prescription version. I am not affiliated with the brand, it's just what was available at the chemist. You are supposed to take a break after 3 months of use.

- The product was quite harsh for me, and I noticed an increase in redness and small acne marks over the course of treatment. It is very occlusive and contains some petrolatum, I believe this is what my skin didn't like so much.

- Sorry for the low quality images, but I estimate that I saw a 30% reduction in pigment after I'd finished the three months. The sun spots are still there, but have lightened a modest amount. I also believe I saw a modest improvement in texture as the cream contains 1.5% Salicylic Acid.

I am happy with the reduction in pigment but could frankly do without the redness or acne marks. I wasn't expecting them to disappear in three months but the trade-off in other skin concerns wasn't quite worth it for me.

Next, I will try returning to Adapalene and will layer it with 5% tranexamic acid cream (Celimax) as I have heard the combination of retinol and tranexamic acid can yield similar results to hydroquinone. If I don't see results, I will try laser.

Thank you!

https://preview.redd.it/4fgrs0hv2f0h1.jpg?width=1703&format=pjpg&auto=webp&s=1203a401152fd67c3dc1a2ff7e1d6f89bf66544a

https://preview.redd.it/jaonn0hv2f0h1.jpg?width=1766&format=pjpg&auto=webp&s=61a30442b5822fa7f6f407a7439eb059e5046e1b

reddit.com
u/Impressive-Fall-7015 — 11 days ago

Experience with Hydroquinone for dark spots

Hello everyone,

This post is intended as a review of my experience with hydroquinone for dark spots, for anyone interested in trying it themselves.

- I am 37, male and Australian. My melanin distribution is a Fitzpatrick 2 or 3, where I can tan but mostly burn.

- I have been using sunscreen daily since I turned 30, but the last few years I have noticed some sun spots developing on my cheeks. This may be due to not re-applying sunscreen throughout the day.

- I used John Plunkett's Superfade Cream twice daily for exactly 3 months. This is an over the counter option we have here in Australia and I am not affiliated with the brand. It's just what was available at the chemist.

- The product was quite harsh for me, and I noticed an increase in redness and small acne marks over the course of treatment.

- Sorry for the low quality images, but I believe that I saw a 30% reduction in pigment after I'd finished the three months. The sun spots are still there, but have lightened a modest amount.

I am happy with the reduction in pigment but could frankly do without the redness or acne marks. I wasn't expecting them to disappear in three months but the trade-off in other skin concerns wasn't quite worth it for me.

Next, I will try returning to adapalene and will layer it with 5% tranexamic acid cream (Celimax) as I have heard the combination of retinol and tranexamic acid can yield similar results to hydroquinone. If I don't see results, I will try laser.

Thank you!

https://preview.redd.it/3cgau2udf90h1.jpg?width=1703&format=pjpg&auto=webp&s=3c8abfdd07e479c347b24c4a016dfd779c338c6f

https://preview.redd.it/wyc4e3udf90h1.jpg?width=1766&format=pjpg&auto=webp&s=235e6378a896b6c42ca28cc6726dbd5674509341

reddit.com
u/Impressive-Fall-7015 — 12 days ago