u/Initial_Compote_1476

Seeing if anyone has any experience or thoughts. I was steadily losing 2.5-3 pounds a week on 2.5mg (I’m a super responder… not trying to flex here in any way as I know this is super unusual)… week 5 bumped up to 5mg and lost 3 pounds with minimal side effects. Took my second dose of 5mg and had horrible side effects… I was nauseous with severe diarrhea for 6 days…. I was so weak and tired and couldn’t get my electrolytes balanced and eventually needed IV fluids to partially recover…. I ended up losing 5.5 pounds due to dehydration.

The doc I saw suggested I go back to 2.5mg as she felt I was losing too fast (at 3lbs a week) and I didn’t argue (side note… I bought through trinity meds as they have pay over time option… I stupidly didn’t research their customer service and they are abysmal …. I have reached out many many times and have gotten no response). I waited one additional day to let it clear a bit and then took 2.5mg. I’ve gained back 3.5 pounds of what I lost that week which isn’t unexpected since I’m actually hydrated now, however It’s been a few days and I don’t feel like it is working the same…. I’m hungrier, there’s more food noise

My question is this…. Is 2.5 maybe not enough? Do I just need to maybe build up the level a bit more? I won’t go back up to 5…. But would maybe do 3mg. Anyone else have an experience like this?

I’ve been on tirzepatide for 5.5 weeks. Last Saturday I took my first increased dose and noticed some more nausea but nothing else. This past Saturday I took the second increased dose of 5mg and have been miserable. In the first 24 hours I was super dizzy/felt like I would pass out so I drank more water and ate more often thinking it was either because of dehydration or not enough calories… then after I hit the 24 hour mark it went downhill. I was super nauseous all day and couldn’t eat but that transitioned to mass amounts of watery diarrhea all night and into the next morning. I spent the day resting and drinking drinks with electrolytes and felt a bit better but at bedtime the diarrhea returned with a vengeance. It seems to have calmed a bit now but now I’m absolutely exhausted (which I know is in part due to difficulties staying hydrated and not eating a whole lot). Walking up stairs tires me out… I took a shower and now need a nap… it wipes me out that much. It’s been 76 hours since my last shot… please tell me this is going to get better! I have already emailed my provider about going back to 2.5mg… I was losing weight steadily.