r/TirzepatideRX

I just opened a vial from pro rx that has bud date of 1/15/27 & noticed white stuff in bottom of vial😳 I shook it lightly & it’s bubbly - what should I do?

Hi there, looking for folks who have BCBS FEP and are taking Zepbound. Can you please tell me what your copayment is? Mine has been all over the place. Thanks for your insight.

I’ve been on tirzepatide since mid February 2026, the last 3 weeks I have experienced bad side effects, worse than when I started, panic attacks, extreme fatigue, nausea, etc. I’ve done micro doses from the beginning. has anyone started on tirzepatide and switched to semaglutide and done better with it?

I'm going to switch from wegovy to Tirzepatide..

..Would each of you let me know how much weight you lost in your 1st & 2nd month using Tirzeptide / Zepbound / Monjaro.. And what your side effects were?

I just started Tirz/B6 at 2mg today and will titrate up 1mg/week after two weeks. Any tips for avoiding gastrointestinal issues or things that have helped you along the way?

I have healthy habits and am not obese, but developed insulin resistance after going through years of unsuccessful fertility treatments where I was injecting myself with all kinds of hormones. I have managed it fairly well on Metformin, but the scale/body fat will not budge without being hyper vigilant with calorie counting, and that is not good for my mental health.

I also deal with anxiety and depression, and my mental health nurse practitioner said GLP-1s are being studied as a way to address these conditions, so I’m hopeful I will notice a change!

I am hoping to drop some weight, but more importantly support my metabolic health, appetite control, and find freedom from food noise.

Hi!!!

I’m new to tirzepatide I just picked up my dose!!! I was on wegovy from may 25’ to dec when my insurance cut me off. I lost 30lbs in that time, slow loser as they say. I gained 17 back but truly didn’t stick to a diet my hunger came back full force.

Anyway, has anyone done the switch? Things to look out for that is different? Tell me the good bad and ugly!!

Thanks :)

For context, I lost over 60 lbs on 1.75 mg of ozempic. I had to stop cus my insurance stopped covering it and gained back 50 lbs. I then started again when I found out my insurance covers wegovy instead, I’ve been on the 1mg dosage and so far I’ve lost about 20 lbs since beginning of March through a mix of calorie deficit and strength training. The appetite suppressant aspect really isn’t that effective anymore.

I have PCOS and wow my sugar cravings are insane and unmanageable at times. My endo at the time thought it would be a good idea to start on tirzepatide instead as it’s better for inhibiting food noise. My insurance approved and by next week I’ll be transitioning to the 2.5mg starting dose of Zepbound.

I’m a little scared, seeing that I’m steady losing weight but afraid that switching a medication will stall that weight loss. My question really is, given that tirzepatide is proven to be more effective than semaglutide for weight loss, will I see significant scale changes in the first month of 2.5mg zepbound? Is 2.5mg of tirzepatide stronger than 1mg of semaglutide?

I've been using Fitbit since 2012 and now that Google's taking over it well, let's just say enshitification is a real thing. I love glapp for my Tirz logging (they even track your supply and tell you how much you have left!) and they did say they are working on coming out with a food tracker but I'm just curious what everyone else uses. Trying to find something that's free or at least not super expensive

My girlfriend (mid 20s) recently moved from Europe to USA and is struggling greatly with food noise. We think due to the additives in US food. We have heard good things about micro-dosing tirzepatide to reduce food noise.

She wants to hear from a fellow ballet dancer that they have felt good in their bodies while using tirzepatide. She really trusts ballet dancers because they understand their body very well.

If you are a current or former ballet dancer using tirzepatide please dm!

I wanted to tell you my story for people out there on Sema just as a warning - not to stop using it - but just be aware of this potential side effect. While there is still more research to be done on this drug, I do attribute my having to remove this organ because of my rapid weight loss.

I started Semaglutide 15 months ago. I switched to Tirzepetide after about 5 months and the weight came off faster. My weight was 225. I’m currently 54 years old and do not have diabetes. I use a telehealth prescription. I’ve had incredible weight loss success, losing 90 pounds over the last 15 months.

About 5 weeks ago, I had an attack. At first it just feels like gas, but the pain doesn’t go away. It’s just gnawing and lasted the night. And it was more concentrated under the right rib cage, permeated to my back, and was accompanied by some light nausea. After some research, discovered it might be gallstones. I powered through it, knowing I would need to go see a doctor soon. This past weekend I was out of town, had a meal and this time it was MUCH worse. Doubled over in pain, vomiting. Went to the ER, and after some testing confirmed it was my gallbladder. I have to get it removed within the next week or two and until then, I’m on an all-liquid diet.

I do attribute the gallbladder / gallstones to my rapid weight loss for a few reasons: 1) I never experienced any gallbladder issue prior to my Sema/Tirz use. 2) I’ve always been a generally healthy eater. While I’m not a vegetarian, I prefer vegetables. I avoid processed foods (fast food), generally. I’ve heard that gallstones form after a period of time - like years - and an attack occurs when your system finally fights back. But I find it odd that this would be the case when I’m eating less and haven’t changed the kinds of food I eat, more or less. If anything, I’ve been eating healthier. (I’ve read that rapid weight loss takes the cholesterol in the fat and gets in your system and can form a sludge in your gallbladder.)

I don’t regret taking the drug, but in retrospect, I wish I had been more aware of this potential issue being about the rapid weight loss vs the actual drug. I may have slowed down the pace and increased the dosage over a longer period of time. (I guess this may be one of the downsides of doing telehealth, but the cost is so significantly less that I wouldn’t have been able to afford the name brand, and my insurance doesn’t cover it, especially because I am not diabetic.

I was using a 503A in Idaho. My PCP of 12 years sent an RX with medical necessity for compounded. This pharmacy, while small, does FAR more scripts than 4 a month. I panicked and decided to go to LILLY DIRECT but the compounded with B6 and B12 in a custom dose works much better.

What is the time frame for 503A pharmacies to be shut down, do you think?

Im new to GLP-1s, I just wanted to know if anyone has used fifty410 as their provider for triz, they charge $249 for 8 week supply and $399 for a 12 week supply. I noticed that my “nurse practitioner” looked a bit AI-generated.

Just looking for tips or if anyone gets their Triz from another TRUSTED provider.

Thank you guys so much!

Just a short post to say I'm totally blown away by this first week. I started on the 2.5mg starter dose. At first I thought the lack of food noise I was experiencing was a placebo effect, but it definitely isn't - I'm just not thinking about food like I used to and I no longer have the visceral cravings I had before! I've even been purposely trying to think about my trigger foods to see if I have a mental or physical reaction and... nothing. Absolutely the craziest thing I've ever experienced. I finally feel like I can think about food like a "normal" person. I can't wait to see what this journey is like moving forward.

If you're reading this and you're still on the fence about giving tirzepatide a try: just try. It very well could be a life changing experience.

Im currently doing 3.75 1 a week but thinking of doing 2.5 every 3 days so total is 5 mg a week but how do I handle vacations?? Im going on a week vacation soon and cant pack it cause it needs to stay cold?????? Heeeelp

For context, I have been on compounded tirz since April 2024, so 25 months. I have had lots of ebbs and flows. At my lowest, I had lost 69 lbs. However, 25 has creeped back on and will NOT budge. I have been at the max dose my place prescribes, 14.5, for 8 months. Every week it’s the same thing. For the first three days after I take it, I have barely any appetite and drop like 4 pounds, probably all water. For the rest of the week I have a completely normal appetite and by the time it’s time to take the shot again, I have lost absolutely nothing. I’m just looking for suggestions because I am feeling so defeated. When I say stall, I’m not talking weeks. This has been about five months. I am nowhere near a normal BMI so it’s not like I am at the lowest I could or should- be the very highest end of my BMI is 14 pounds under where I am right now. Just looking for any suggestions of people who were in the same boat and found a way to breakthrough. Whether it’s increasing in dose a little higher, maybe breaking the dose into two different shots a week. I don’t know, I just need help. :( Thanks for listening.

I am on my first set of injections, and have already reached my target weight. I have a feeling my doctor will take me off of it, but isn't this a long-term thing? I was never really given any information other than how to inject, what amount, and to never reuse needles.

I have two injections left but the vial is leaking when i turn it upside down, and I'm not sure what to do. I didn't really want to suck it all up off my hand. I would ask if theres another vial but I don't want to be seen as wanting to become skin and bones, I just want the rest of what's spilled out. I only had enough for this week.

Either way, I think my treatment ends 2-3 weeks earlier than I was told. I'm not exactly sure what to do at this point.

I’ve (30M) been on a GLP1 for almost five years now, with about three of those years being Tirzepatide.

My doctor seems to think there is no correlation between my worsening vision and Tirzepatide use. She has stated Tirzepatide should help reduce retinopathy if anything.

The vision in my right eye has gotten significantly worse in the past year and I don’t know what to do. My eyes are dry and I stare at screens a lot, but I’ve only recently started having issues.

A friend of mine who has also been taking these shots has also said she’s never had poor vision but only recently started to need glasses for the first time in her life.

Does anyone have any feedback or advice regarding this? I’m terrified Tirzepatide might be ruining my vision.

I’ve been on mounjaro now for about 5 months. For the first month and a half my injections were completely painless. Lately my injections have been stinging every time, despite the dose (2.5 mg) and method (auto-injection pens) being the same. I only inject in my stomach as I tried my thighs and arms and did not like it, but I rotate around the stomach area. I do leave my pens out for at least an hour, sometimes several hours to come to room temp. I also make sure that the alcohol dries before I inject. Aside from that, I also ice the spot beforehand and use fluconazole spray afterwards to prevent injection site reactions and that has worked to prevent welts. I don’t think I usually feel the needle at all but the stinging is from the medication. Anyone else had this experience? Any tips other than the things I’ve already tried?