Increased sertraline from 75mg to 100mg, now feeling flat and mentally restless. Anyone else?
I (34F) have been on sertraline for 4 months for anxiety, which got worse in the postpartum period. I titrated up over the first weeks, 25mg → 50mg → 75mg, and eventually stabilized on 75mg, where things actually went pretty well — my anxiety was under control and I felt reasonably like myself.
About 4 weeks ago I increased to 100mg, mainly to see if there was more improvement to be had. Instead of feeling better, I now feel emotionally flat, I struggle to feel joy or excitement about things I normally enjoy. On top of that, my head feels busier than it did on 75mg, which is the opposite of what I expected. Sort of an internal restlessness rather than calm.
Since the increase didn't really add anything except side effects, I'm planning to discuss going back down to 75mg with my doctor. Has anyone experienced this, where a higher dose made you feel worse (flat + restless) and dropping back down helped? How long did it take before you noticed a difference after lowering?