▲ 8 r/Psoriasis+1 crossposts

Has anyone had success at a specialized PsA clinic after failing many treatments?

I’ve had psoriatic arthritis for 12 years and have tried Humira, Cosentyx, Tremfya, Otezla, methotrexate, Rinvoq, Xeljanz, Simponi, Stelara, and Remicade with cyclosporine. Some helped temporarily to a decent level (max 70-80% normality), but I’ve never reached remission, and several stopped working or caused side effects.

My biggest issues now are widespread enthesitis and axial symptoms. I’m wondering whether a dedicated PsA clinic might offer a more comprehensive assessment or spot something that a regular rheumatology practice has missed.

Has anyone been treated at a specialized clinic such as the UHN Psoriatic Arthritis Clinic at Toronto Western Hospital, or a similar academic PsA center?

I’d especially like to hear from people who:

  • Had already failed many biologics or other medications
  • Struggled mainly with enthesitis or axial symptoms
  • Received a different diagnosis, treatment strategy, imaging, or combination therapy
  • Finally improved after being considered a difficult or treatment-resistant case

Did the specialty clinic do anything meaningfully different? Was it worth the referral and wait? If you attended the UHN clinic specifically, what was your experience like?

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u/MMA-Head — 3 days ago

Minor Injuries…Major Response

Anyone else find that fairly minor bumps, bruises, and injuries impact around joints/tendons tend to cause over blown reactions?

It’s especially worse for me when enthesitis is less controlled. In recent news… a spouse of a family member decided to give me a huge slapping dap greeting… now my middle wrist is super sore for the passed 2.5 weeks, and the rest of my body started to flare in different spots. Getting under control with treatment adjustments.

Can anyone relate? Tired of feeling like bubble boy, I used to kickbox and compete before this disease….

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u/MMA-Head — 20 days ago

I’m seeing a functional medicine doctor for the first time. She is recommending the below stack as part of my treatment. Any experience with these good or bad? Life changing by any chance?

The GLOW stack contains three peptides:

  1. GHK-Cu (copper tripeptide) — collagen, elastin, skin repair

  2. BPC-157 (gastric-derived pentadecapeptide) — tissue healing, inflammation

  3. TB-500 (thymosin beta-4 fragment) — cell migration, angiogenesis, recovery

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u/MMA-Head — 4 months ago