The title "Klutzy Class Monitor and the Girl With the Short Skirt" really does the show a disservice.
This post is mostly just an endorsement for the show because - if you're anything like me - that title immediately made you think of a horny, male-focused story with a bland MMC and generic "waifu" FMC.
That second part especially, "Girl With the Short Skirt," (along with anime's general wierdness) made me assume 90% of the budget would be focused on upskirts. Imagine my surprise when I wasn't greeted with a single panty shot throughout the entire show... even if that's not a high bar.
In reality, the story's FMC is the main character, and it is actually an extremely cute story all together. It's primary themes (and it does have themes) seem to revolve around family, and as such, the main characters' families actually play a large role in the story. That's probably my favorite aspect of the show, and the title gives no indication that it's the case. At least the title "You and I are Polar Opposites" (despite being similarly generic) give an impression of the overall themes and conflict.
Honestly, I don't have much else to say. If the title turned you off as much as it did me, give it a shot. Also, what are some other cases of similar cases? Cases of titles giving you the completely wrong idea?
As an aside, the author generally has some odd titles seeing as his (arguably) most popular manga is called "Molester Man." No clue what it's about, but I'd be remiss if I didn't include that fun fact.