u/Ok_Shake_3194

▲ 1 r/PMDD

Pain increases during hormone shifts during cycle, any help/ shared experience/ tips are greatly appreciated

Hi, I began having extreme hives cyclically at start of 2026 and constant stomach pain leading to Eosinophilic Gastritis and MCAS diagnosis. My OBGYN diagnosed me PMDD last week based on the symptoms being driven by my hormonal fluctuation and mast cell stabilizers not alleviating pain. Hives, anxiety, waking 3x a night, and PAIN- aching feeling like Ive been punched across my upper abdomen and ribs, burning under left rib cage which wakes me up in the morning. Does anyone here experience increased stomach pain/ burning days leading up to their period and/or ovulation. If yes, any ideas, meds,supplements to try that have helped. Currently on zyrtec, famotidine, progonal cream for luteal, trialing ketotifen .5mg and now zoloft )Thanks!

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u/Ok_Shake_3194 — 10 days ago

Anyone's symptoms increase when hormones fluctuate?

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Hello, beginning of 2026 I began having extreme hives cyclically, which progressed to constant stomach pain leading to Eosinophilic Gastritis and MCAS. I have been taking Cromolyn Sodium since the start of July. Cromolyn plus 6 fed+ low histamine diet has helped A LOT.

Hives, anxiety, waking 3x a night, and PAIN- aching feeling like Ive been punched across my upper abdomen and ribs, burning under left rib cage which wakes me up every morning no matter what I take.

Does anyone here experience relief in their symptoms then it all comes crashing down again around period and ovulation? Please share any additional ideas, meds,supplements that have helped specifically with during hormone fluctuation. Thanks!

reddit.com
u/Ok_Shake_3194 — 11 days ago