Wild Lettuce + GABAergics is an incredible combo. Any plans for an ND extract?
Hey everyone,
I recently experimented with adding Wild Lettuce to a heavy GABAergic stack I run (Baikal Skullcap, Apigenin, Lemon Balm, Ecklonia Cava, plus Matrine and NAC), and the synergy was surprisingly good.
If you haven't looked into Wild Lettuce (Lactuca virosa), it's historically known for mild analgesic and sedative properties. It seems to modulate adenosine pathways and voltage-gated ion channels to relax the body.
On its own, it’s great for physical tension, but combining it with the heavy GABA up-regulation from things like Lemon Balm and Ecklonia Cava created a profound sense of physical heaviness and mental quiet. It perfectly filled the gap for somatic (body) relaxation that pure anxiolytics sometimes miss.
Has the ND team ever considered working on a standardized Wild Lettuce extract? I'd love to see what a highly dialed-in, ND-quality version of this would look like for a sleep or physical relaxation stack.
Let me know if any of you have messed around with it!