u/Own_Pie7565

What is legitimately the cheapest glp1 out there right now?

I really want to start taking a GLP-1, but I do not have a lot of extra money in the bank right now. I know these can get incredibly expensive. For those of you who are doing this on a strict budget, which GLP-1 is actually the cheapest option available? I just want to figure out a way to get started without completely draining my account.

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u/Own_Pie7565 — 3 days ago

Retatrutide data showed solid weight loss, but I'm also watching the cardiovascular risk markers

The TRANSCEND-T2D-1 trial reported that high-dose patients lowered their A1c by about 2% and lost around 17% of their body weight in just 40 weeks. But the drug also lowered key cardiovascular risk markers like non-HDL cholesterol, triglycerides, and systolic blood pressure, which might be just as important for someone's long-term health as the number on the scale

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u/Own_Pie7565 — 5 days ago

Has anyone else noticed that carbonated drinks feel completely different on Mounjaro?

I used to love sparkling water and the occasional soda, but now carbonation feels like it sits in my stomach for hours and makes me uncomfortably bloated. Even a small can of seltzer is too much. Is this a delayed gastric emptying thing, or am I just getting sensitive to bubbles?

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u/Own_Pie7565 — 8 days ago

been on reta for a bit and not counting calories, should i be worried

27M here, been on reta for a little while now and honestly i haven't been tracking anything. no calorie counting, no macros, nothing. just eating the way i normally do and hoping the medication handles the rest

the thing is rice is basically a non negotiable for me as an asian. breakfast, lunch and dinner, it's just part of how i eat and i'm not really willing to give that up. culturally it's just how things are at home

so far i've only lost around 2kg which i know isn't a lot. i'm not sure if it's because i'm not tracking, because of the carbs, or if i'm just a slow responder. honestly could be all three

should i actually start counting or does reta eventually just do its thing regardless? would love to hear from people who didn't change much about their diet and still saw decent results

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u/Own_Pie7565 — 12 days ago

I have type 2 diabetes. My A1C dropped from 8.2 to 5.4 on Mounjaro. My insurance sent a letter saying they would no longer cover Mounjaro because my diabetes was "well-controlled" and the drug was now "maintenance therapy." To keep coverage, my doctor had to document that my A1C would get worse without the drug. She literally had to write a letter saying "patient will likely regress if medication is discontinued."

I was terrified they'd deny it anyway. I started eating more carbs before my next A1C test (under doctor supervision) to prove the point. My A1C came back at 6.1. Still in range, but higher. Insurance approved the renewal. I feel dirty. I intentionally hurt my health markers to satisfy an insurance algorithm. Has anyone else done something like this? I hate that the system forces us to choose between being healthy and getting coverage.

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u/Own_Pie7565 — 16 days ago

Potenje pri športu

Imama težavo, da se zelo hitro začnem potiti. Posledično sme takoj moker in izdaja me vonj. Kaj priporočate? Ali je to res determinanta ali se potenje kako vsaj malo zmanjšat. nerodno je, ker že zdaj moram menjat kratko majico v službi 2-krat na dan.

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u/Own_Pie7565 — 17 days ago

The Therapeutic Research Center of America just published survey results from over 2,100 GLP-1 users. 4.3% reported injection site reactions (redness, swelling, itching). 0.8% reported systemic allergic-type reactions.I'm in the 4.3%. Every stomach injection gives me a red, itchy welt that lasts 3-4 days. It's not painful, just annoying.

After months of trial and error, I found something that works: injecting in the upper outer thigh instead of the stomach, and applying an ice pack immediately after. The welts are now 75% smaller. Hope this helps others too.

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u/Own_Pie7565 — 20 days ago

I am a 19 year old guy sitting at around 135lbs and 5'6". I am pretty lean, probably around 12% body fat. My dad is lucky as hell at 6'1" and my mom is 5'0". As you can guess I am miserable about my height, even though I am happy with my gym progress. Being a short dude is just rough. My confidence is nonexistent and I even started doing BJJ just so I don't feel like I would get destroyed by taller guys if something happens. It feels like women just look right past me, and dating apps are a complete waste of time unless the girl is really short.

For context, I have been stuck at 5'6" for almost three years now. I maybe grew half an inch in that time. I am pretty sure I am done growing naturally, so what is the best route for someone in my shoes? I don't have thousands to drop on real HGH.

Is Mk-677 worth looking into? How do people even get this stuff? Will a doctor actually prescribe it? Is this even a smart path to go down? Are my growth plates definitely sealed by now, and if they are, is there any chance of gaining height anyway? I saw some fitness YouTubers claim they grew an inch or two in their early 20s. Let me know what you guys think.

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u/Own_Pie7565 — 22 days ago

I’m a member of a slack group for bioinformatics professionals (mostly academic researchers. Last week I asked them how they think about rare side effects when using GLP-1s themselves. And the consensus was pretty interesting. One researcher pointed out that “rare side effects” in clinical trials are defined as occurring in less than 1 in 1,000 patients. But with millions of peple now on these drugs, a rare side effect could affect thousands of people. Another noted that most rare drug reactions are idiosyncratic (unpredictable and not dose-dependent), meaning you can't really screen for them ahead of time. A third pointed out that obesity itself carries serious long-term risks (cancer, heart disease, kidney failure) that are much more common than any rare side effect from GLP-1s.

What stuck with me was that they all said they take GLP-1s themselves, despite knowing the unknowns. Their logic? The known long-term risks of obesity outweigh the unknown risks of the drug.

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u/Own_Pie7565 — 23 days ago