u/Queefaroni420

That’s all I wanted to say. I guess most people don’t experience pain, but every time the nurse moved the catheter, it felt like someone was stabbing a knife straight into my urethra. And my body kept pushing it out, so she had to reposition it multiple times. Also, it would trigger pelvic floor spasms which would then jiggle the catheter and cause another flash of stabbing pain. My nurse was really an angel about it though and kept checking in with me to make sure I wanted to continue. I didn’t want to but I had to get this test done in order to get any kind of treatment so here we are. Now I guess I’ll just continue pissing blood and feeling like I’m being stabbed every time I pee for the next day or two.

I have a vaginal vault prolapse caused by my uterus & bladder coming down, and a rectal prolapse. It’s likely from my Ehlers-Danlos Syndrome. I have a urodynamic study tomorrow, because it’s required before I can get surgery. I’ve never had a urethral catheter and I’m really afraid of the pain it could cause. Both with insertion and triggering bladder spasms. When I get them, the spasms last about 2 hours and the pain is by far the worst thing I’ve ever felt (and I dislocate my shoulder in my sleep pretty often). I come close to fainting from the pain. I just really, really do not want to deal with that. I just want to get my surgery and leave this behind me. 😭

After a bad flare up of inverse psoriasis and paradoxical eczema, which then got infected with klebisella and staph, I am switching from Taltz to Simlandi. Is there any meaningful difference between Simlandi and Humira? What even is a biosimilar and why does it exist? LOL

I got paradoxical eczema from Taltz and will have to switch to a different biologic. I’ve talked with my doctor about this, and some options could be switching to Bimzelx and adding Dupixent in case the Bimzelx also triggers eczema. I could also switch to an IL-23 inhibitor because they have less of a chance of triggering eczema. The only issue is that they don’t work as well for joint inflammation, which is my main symptom. There is also Rinvoq, but because I get hemiplegic migraines, my stroke risk is elevated, and Rinvoq can increase stroke risk even more. I’ve also read a few case studies where people with Taltz-induced paradoxical eczema were treated with a 2-4 week course of an oral JAK inhibitor and had 90%+ skin clearance. But the stroke risk is a barrier. I am seeing my doctor again tomorrow to hopefully come up with a plan of action.

Has anyone here had this happen to them, and if so, how did you go about treating it? How long did the eczema last for you?