The loophole in Trump’s obesity drug deal with Eli Lilly and Novo Nordisk

The loophole in Trump’s obesity drug deal with Eli Lilly and Novo Nordisk

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Drugmakers offered GLP-1 discounts in exchange for more volume. They mostly got volume

By John Wilkerson

June 30, 2026

John Wilkerson, a Washington correspondent, is the author of D.C. Diagnosis, a twice-weekly newsletter about the politics and policy of health and medicine.

WASHINGTON — The Trump administration’s grand bargain with drugmakers on GLP-1s was based on a simple premise: lower prices in exchange for higher sales volume. Instead, the companies secured higher volume without the lower prices in some cases.

When President Trump’s team of negotiators got Eli Lilly and Novo Nordisk to agree to a monthly $245 price in Medicare and Medicaid in November, that price was supposed to be for all GLP-1s, including those for obesity, which until then had not been covered by Medicare.

But that price was contingent on private Medicare insurers agreeing to cover the drugs for all uses, with a $50 copay. The administration did not publicly mention that condition, but Novo and Lilly recently confirmed it to STAT. 

The plan was for insurers to voluntarily join a pilot program called BALANCE. But in the end, insurers refused, so instead, Medicare is covering GLP-1s approved for weight loss outside of the Part D benefit in a separate pilot program called Bridge. Bridge starts on July 1 and runs until the end of 2027.

Bridge applies only to obesity drugs, so drug companies can continue selling GLP-1s at higher prices for other conditions. That’s one of the biggest shortfalls of the Bridge program, according to a paper by Stacie Dusetzina, a health policy professor at Vanderbilt University Medical Center.

“The most obvious concern is that the potential savings associated with a lower negotiated price for all GLP-1 fills in Medicare Part D will not be realized,” Dusetzina wrote in the New England Journal of Medicine. “Instead, the Bridge will provide access to GLP-1s for expanded indications without any new price concessions for existing use.”

Still, even as the administration touted its deal, the conditions were already ripe for GLP-1 prices to fall. Manufacturing capacity was ramping up to ease supply shortages, some of Novo’s drugs were already subject to Medicare price negotiation, and potential competing drugs were moved into late-stage testing. In late November, Medicare announced negotiated prices of $276.78 a month for commonly used doses of Ozempic and Rybelsus, and $385.63 a month for the highest dose of Wegovy. Those prices go into effect in 2027.

About 16 million seniors are eligible for GLP-1s under current law for treatment of diabetes and cardiovascular disease, according to the Congressional Budget Office, though government data show that only a little more than 3 million seniors took a GLP-1 in 2024.

The CBO estimates that about 12.5 million seniors would be eligible for weight loss drugs. It’s not clear how many will decide to get the drugs via Bridge, but the administration is expected to tout the program as a major affordability issue. Trump has said he wants drug prices to be a top affordability issue for Republicans heading into the midterm elections, and GLP-1s are the flagship of that effort.

The Bridge program also presents an ironic twist. Some seniors who were already eligible for a GLP-1 may pay more for the drugs than those who will be eligible for the drugs for weight loss only. Bridge’s cost sharing is $50 a month. On average, seniors pay $163 to $182 a month for Ozempic. On the other hand, seniors with low incomes would probably pay more in Bridge than they would via Medicare coverage.

The government is expected to spend more on Bridge than it would have on BALANCE, though the administration is mum on the estimated cost of Bridge. The extra cost probably will be borne by taxpayers and Medicare beneficiaries in the form of higher Part B premiums in future years, Dusetzina wrote.

It’s not clear what will happen at the end of next year when the Bridge program expires. There isn’t much incentive for insurers to participate in BALANCE, and drugmakers are better off in Bridge, too. 

Administration officials have said that the Bridge program will help plans prepare for BALANCE by demonstrating how much it would cost to cover GLP-1s for obesity.

But insurance companies don’t have much time to prepare for 2028. Each year, Medicare issues a rule regulating Medicare Advantage and prescription drug plans that sets limits on premiums and other aspects of coverage. Medicare must publish the proposed version of that rule for 2028 coverage by late November of this year. 

Elaine Chen contributed reporting.

statnews.com
u/ReasonEcstatic7417 — 8 hours ago

Eli Lilly delays biologics filing for FDA approval of Retatutride

"The company said major cardiovascular events occurred less frequently ​than expected in both the treatment and placebo groups. But when measuring just the three most severe events - ​heart attack, stroke and death - patients on retatrutide had a 12% higher risk than the placebo group."

The article also states:

"Lilly said it plans ⁠to ​submit a biologics license application for retatrutide to the FDA in the ​first quarter of next year. The company also said full results of the latest trials will be published in medical journals at a ​later date."

Some information about biologics and the Biologics License Application (BLA):

"Expensive biologic medications make up only 5% of prescriptions in the U.S. but account for 51% of total drug spending as of 2024." (source)

Biologics are not allowed to be compounded. (source) However, they are in fact much more expensive to produce than small molecule class drugs or peptides. The advantage for a pharma producer when a product in the BLA procedure is a 12 year market exclusivity period, where biosimilars as reference products will not be approved by the FDA to enter the market. (source, p. 32)

Edit:

Some more background about the question on biologics approval:

In 2023, the FDA already denied the approval of another drug as a biologic (Alzheimer's disease) by Eli Lilly before. (source)

In 2024, Eli Lilly sued the FDA for its terms on biologics classification. (source)

Currently, Eli Lilly is suing the FDA again to reclassify retatrutide as a biologic rather than a traditional drug. (source)

reuters.com
u/ReasonEcstatic7417 — 1 day ago

EU-Kommission hat die Novo-Pille genehmigt

Nach den USA, UK, Vereinigte Arabische Emirate und in Bahrain nun auch die Zulassung in der EU (Europäische Kommission hat das go gegeben und das Unternehmen darf mit dem Marketing innerhalb der EU beginnen). So weit ich weiß haben die schon einiges vorproduziert; es sollte also bereits noch in diesem Jahr verschreibungsfähig sein

novonordisk.com
u/ReasonEcstatic7417 — 10 days ago
▲ 1.3k r/wallstreetbetsGER+1 crossposts

SPCX first major unlock is bigger than the entire IPO float

I was trying to understand why SPCX is struggling to hold a bid after the Nasdaq100 inclusion, and the lock-up math is probably part of the answer.

The IPO issued 638.9M Class A shares at $135, including the full greenshoe. The first major post-IPO unlock is 911.5M shares after Q2 results + 2 trading days. That alone is 142% of the IPO-issued shares. If the extra Q2 price trigger is met, another 456M shares can unlock, taking that first window to more than 2x the IPO-issued share count.

Lock up dates matter, but the real risk is scale: how many shares become eligible for sale versus the IPO float. I find this useful when accumulating newly listed companies, so this calendar may help someone else.

Data fed into chatgpt: SEC 8-K for IPO shares/pricing and the SEC 424(b)(4) lock-up schedule. Tables generated by chatgpt.

u/Imaginary_Cat_3802 — 14 days ago
▲ 485 r/wikifolio+1 crossposts

SpaceX ist ein milliardenschwerer scam

Yo ich weiß nichts neues, aber trotzdem Affenweiterbildung und Infopost für alle Neuprimaten. Wollte das posting vom amerikanischen Unter gerne hier teilen, ging aber leider nicht

Alte NASDAQ-Regeln:

- Stock muss drei Monate vor sich hin reifen

- Stock muss mindestens 10% der Aktien für Kleinanleger handelbar machen

Neue NASDAQ-Regeln mit SpaceX-Extrawurst:

- Stock darf schon nach 15 Tagen im NASDAQ gelistet werden

- Stock darf 4% der Aktien für Kleinanleger handelbar anbieten

Zusammenfassung:

Kleinanleger können beschleunigt zu Exitliquidität werden und amerikanische Pensionskassen sind durch das listing gezwungen, diese Scheiße zu kaufen.

Zwei lesenswerte Artikel auf Englisch hier und hier

tl;dr: Finger weg von SpaceX

Edit: Link zum Infopost vom Original-WSB in den Kommentaren hinzugefügt

u/ReasonEcstatic7417 — 2 months ago

Market recap von heute

Wir alle sind ja schon einiges gewohnt, aber heute kamen ja mal wieder absolute BANGER:

- Website des Department of War veröffentlicht UFO-Feldstudien, weil nach der 3945. Friedensverkündung nicht wieder die Epstein Files zum Thema werden sollen

- Intel, qualifizierter shitstock, Micron, kein shitstock, Monster Energy, definitiv shitstock, steigen nicht mehr, sondern rasten völlig aus

- Rheinmetall sucht den Boden nach Crack-Steinchen ab

- FED wird bagholder von US-Staatsanleihen (Stand heute: 65,9%, höchster Stand nach Weltwirtschaftskrise 2008 mit 68,5%) -> könnte das ein Covid-Stimulus und Inflationstreiber sein?

Dies soll kein Bärenpost sein, weil ich keine Expertin für nichts bin. Vielleicht einfach nur der Hinweis: Passt gut auf euch auf!

Haut gerne noch mehr banger von heute raus, ich freue mich über updates

reddit.com
u/ReasonEcstatic7417 — 3 months ago

NVO movement today:

"Novo also announced that, pending regulatory approvals, the Wegovy pill will launch outside the U.S. during the second half of 2026."

Furthermore:

"Novo’s results come as investor sentiment around the company had slowly begun to recover following the launch of the Wegovy pill in the U.S. in early January, which analysts hailed as 'one of the best launches ever.'"

Source: https://www.cnbc.com/2026/05/06/wegovy-glp1-weight-loss-novo-nordisk-earnings-stock-nvo-ozempic.html

u/ReasonEcstatic7417 — 3 months ago