u/Sandman4130

I am unfortunately in the “low,” percentage of people with heavy fatigue from Keytruda. It’s getting to me. I am finishing month 5 of the therapy and I feel flat out awful: debilitating fatigue, my skin is crazy reactive to heat, had some sores start up in my mouth, etc…

Reading that there is a not insignificant chance that these are now how I feel, even after I stop taking Keytruda (hopefully)… well, like I said, it’s getting to me.

I typically power through and try not to complain. I was in the best shape of my adult life when I got the diagnosis in December 2025, and of course that’s not the case now. I feel terrible whether I work out or do anything or not, so I have at least been forcing mussels back to the gym and all the things I do normally, even if with less duration or intensity.

I am fortunate that so far, I do not have any other tumors or growths and that my testing is all still positive. I have scans coming up over summer that will show what’s up. I grateful for the fact that the cancer seems to have been managed so far.

But when I read that 96% of Keytruda users have long term effects, mostly “mild.” But that 4% have severe long term effects, I had a bit of a moment.

Just bitchin’ to save my wife from having to hear it.

Eagle’s Mountain Raceway in TX is one of my favorite tracks and the location of my first track day with my ‘16 1290 SDR. It was my first track day in two years so I was intentionally cautious, but even still I was among the faster riders in my group.

I come off a 150hp FZ1 so the power was not overwhelming but it was clearly more with more torque. Low, skimming power wheelies were the norm driving out of corners.

The front end felt planted and it handled well. I had read that for some, the front end can be not so confidence inspiring at pace, but it felt great to me.

It took a few laps to get comfortable shifting coming off a super smooth 4 cylinder but no big deal. I wound up leaving it in third gear for most of the time because I was focused on being smooth and not so much raw lap times. I decided to stay in third after I hit the limiter a few times on the longer straights by not shifting in time. I’ll get there.

A couple of things to work on: 1) I think I need stiffer springs. I weigh 240 in gear and while the stock springs were not wallow-y, it could have felt more “railed.” 2) My corner entry speeds need to improve. I was being cautious all day and never apologize for that: the number one goal is always getting home under my own power and keeping the rubber side down. But between my caution and getting accustomed to the substantial engine braking, I have something to work on for the next track event. 3) The Competition Werkes decay and muffler are insanely loud, too loud for my preference. Even with the baffle in and quality earplugs, it was painfully loud at 10k rpm. Looking for another option without breaking the bank. I wish the BODIS, dual muffler was less pricey. Considering the MIVV dual or even a Yoshi.

Input sought: Where to go for help calculating and purchasing new front and rear springs? Thoughts on the MIVV dual muffler?

Keytruda long term effects: