Hypercalcemia and hypercalcuria not r/t hyperparathyroidism

Age 38

Female

65in

Height

Weight

165lbs

Race

Caucasian

Duration of complaint is 4-5 months.

Current medications

Wellbutrin 300mg XL

Norco prn

Vit d3 1000mg daily with meal

38yo F, 165lbs, 65in an I am from the USA. I do not smoke. I am a registered nurse. I am a recovering alcoholic and I have been sober for 9 amazing years and I am grateful to he alive.The only medical hx I have is a tubal ligation and then a partial hystrectomy in April 2026 and multiple kidney stones that started in 2011. I was seen in the ER on May of 2026 for complications from my hystrectomy. Labs were drawn and calcium was elevated at 12.4. I was given 40mg of IV Lasix and 1L of NS and calcium came down to 9.7. I was of course referred to endocrinology and have had multiple tests done. Calcium remains consistently elevated but has dropped to 9.7 on a few occasions. Hyperparathyroidism has been r/o due to low PTH levels. My 24 hour urine calcium has been off the charts at 607, 937 and 678. My endocrinologist said thats the second highest urine calcium she has ever seen. Of course I have had multiple kidney stones and currently have several in my kidneys. I also have nephrocalcinosis. My current symptoms are mild to moderate to severe back pain, fatigue, headaches, muscle weakness, brain fog, irritability, anxiety, RUQ pain and mild numbness and tingling in my feet. The back pain is so bad that my PCP graciously allows me to have a few Norco to take when I am in severe pain. CXR was normal. Thyroid and parathyroid US was normal. UPEP was neg, SPEP is still pending. Bone scan has been ordered but not completed yet. CEA, CA 125, cortisol all normal. The only thing slightly low was my vit D and that has been slowly corrected by taking Vit d3 1000 units daily. My endocrinologist states that my labs are all weird and don't make any sense because all the labs they have checked are normal except my urine calcium and serum calcium. My endocrinologist thinks that maybe its an issue with my kidneys and has sent a referral to nephrology. I am so frustrated, disheartened and I am desperate for any answers or thoughts or recommendations. I can answer questions if needed. I am just so tired and depressed from not feeling good and no one has any answers. I would greatly appreciate input. Thank you!

reddit.com
u/SubjectAd1549 — 5 days ago

24 hour urine very high

My 24 hour urine calcium just came back at 933, the last one I did a month ago was 601. I have severe mid and lower back pain. I am concerned. I have messaged my endocrinologist but I have not received a message back yet. Should I go to the ER?

reddit.com
u/SubjectAd1549 — 24 days ago

24 hour urine very high

My 24 hour urine calcium just came back at 933, the last one I did a month ago was 601. I have severe mid and lower back pain. I am concerned. I have messaged my endocrinologist but I have not received a message back yet. Should I go to the ER?

reddit.com
u/SubjectAd1549 — 24 days ago

24 hour urine very high

My 24 hour urine calcium just came back at 933, the last one I did a month ago was 601. I have severe mid and lower back pain. I am concerned. I have messaged my endocrinologist but I have not received a message back yet. Should I go to the ER?

reddit.com
u/SubjectAd1549 — 24 days ago

Frustrated with hypercalcemia.

Last set of labs was a total calcium of 11.8, ionized calcium 2.64meq, pth 14.1, urine calcium 601mg/24hr, vit D, 25-hydroxy 27. Highest calcium level has been 12.4. My endocrinologist just wants to keep rechecking lab work and told me it takes a while to get a primary hyperparathyroidism diagnosis but how many tests do you need? I also take Vit D 1000u daily. I have multipIe kidney stones in each kidney and nephrocalcinosis. Im exhausted everyday, have frequent headaches, abd pain and mood swings. I am very frustrated and feel like I am being strung along. I feel like I should have a diagnosis by now but also, I am not a doctor, I am JUST a nurse by trade, lol. Please share your thoughts and opinions. It is greatly appreciated.

reddit.com
u/SubjectAd1549 — 1 month ago
▲ 2 r/Parathyroid_Awareness+1 crossposts

Confusing lab results related to hyperparathyroidism.

Labs are conflicting and my endocrinologist isn't convinced I have hyperparathyroidism but what else could it be. Lab results as follow: calcium 11.6, ionized calcium 2.62meq, pth 20, vit D 25-hydroxy-29, mag 1.9, phosphorus 3.5, TSH 2.607.

​

Land 2 weeks later as follows: calcium 9.7, pth 66.6, 24 hour urine calcium 601mg/24hrt, Vitamin A (retinol) 70 and CH Q Calcitrol 43.

​

I also have medullary nephrocalcinosis diagnosed on 2 separate CT scans and a history or multiple kidney stones.

​

Can someone pleas offer an opinion on these lab results? It would be greatly appreciated!

reddit.com
u/SubjectAd1549 — 2 months ago