r/endocrinology

Hello everyone! 32F I started tirzepatide in May, toward mid July I started getting a tight feeling in my throat that would come and go. A few weeks ago it started to become constant so I went to the doctor. They ordered an ultrasound and found a 3cm nodule. I’m scheduled for a biopsy next week. My endocrinologist said it has nothing to do with the tirzepatide and could’ve just been coincidental timing but I’m having a hard time believing that. I’m conflicted whether I want to keep using it. My thyroid labs were normal before I started and are still normal. Has anybody else had this experience or similar? I’m totally not blaming it on the tirzepatide, besides possibly this, I’ve had a great experience on it. Just trying to plan out my next steps.

I recently had some blood tests and I’m trying to understand an unusual combination of results.
My results:
25-OH Vitamin D: 6.76 ng/mL — severely deficient
Calcium: 9.8 mg/dL (8.6–10.0) — normal, but very close to the upper end
Phosphorus: 3.8 mg/dL (2.5–4.5) — normal
Magnesium: 2.2 mg/dL (1.6–2.6) — normal
So I thought my PTH must be working hard to keep my calcium level up!
But…
PTH: 9.5 (6.87–64.87) — low-normal
???!!
What I find strange is that my vitamin D is extremely low (6.76 ng/mL), yet my calcium is still near the upper end of the normal range (9.8). And it’s not due to PTH?
Where is that large amount of calcium in my blood coming from? I don’t take any supplements or regularly eat calcium-rich meals.
What I know is that severe vitamin D deficiency can lead to decreased calcium absorption and compensatory elevation of PTH (secondary hyperparathyroidism). So I’m wondering:
If my vitamin D is this low, why is my calcium still this high-normal rather than low or even mid-range? Not because of PTH? And not because of supplements?
Could there be something else maintaining my calcium at this level?
Then will I be doomed if I get vitamin D injected? (I was given 200,000 IU by injection 6 days ago.)
I’m also wondering whether my PTH being relatively low is simply because my calcium is already sufficiently high.
Anyway, I am lost. I don’t know what is happening with my body.
I’ve been suffering from dysautonomia (POTS) for more than a year and taking propranolol every day.
I try to find the root cause, but more weird results keep coming up and making me confused.
Anyone else have the same or a similar experience?
I also got the vitamin D injection 6 days ago and only recently saw the PTH result, so I’m quite scared that my calcium might become too high.

Also, not sure if it’s related, but my B12 is also low

Vitamin B12: 170 pg/mL (180–914) — low
Homocysteine: 23.5 — high
MMA: 0.13 (≤0.40) — normal
Folate: 4.12 (2.30–24.80) — normal

Not sure if any of these findings could be related, but I thought I’d mention it in case it’s relevant.

Hi, I’m 24F and recently had thyroid tests because of neck swelling. My blood test results were:

TSH: 0.002 (0.27–4.2)

FT3: 6.94 (2.0–4.2)

FT4: 2.1 (0.9–1.75)

My thyroid ultrasound showed an enlarged left thyroid with increased echogenicity and normal vascularity, while the right side was described as avascular. No nodules or focal abnormalities were found. There was one right cervical lymph node (1.3 × 0.6 cm). The radiologist's impression was “thyroiditis with associated right cervical lymphadenopathy.” However, the doctor I visited said I have hyperthyroidism and he prescribed Methimazole 10 mg, and I haven't had a TRAb/TSI test, so I don't know whether I have Graves' disease. My question is, does this sound more like Graves' or thyroiditis, and does prescribing Methimazole make sense given the ultrasound findings? Should I ask for other investigations before continuing treatment or just take the meds for now? He says we'll do another blood test after a month of taking the medication. Please advise.

I saw Endocrinologist yesterday to identify any potential autoimmune condition like Hashimoto's, etc. I have been feeling exhausted (extreme fatigue), have gained weight, experienced hair shedding (loss of density), etc. He suggested more comprehensive blood work and not just Thyroid related.

Following is what he ordered

• Thyroid Peroxidase Antibody

• TSH

• CMP

• CBC, platelet & differential

• Lipid Panel

• vitamin B12

• iron TIBC and ferritin panel

• thyroid stimulating immuno-lats

• thyrotropin binding inhibitory immunoglobulin

• Lipoprotein(a) Cholesterol

• PSA, diagnostic

Is the above sufficient for the diagnosis of any potential autoimmune condition? What role Multinodular Goiter play in this? What are the causes of this expanding thyroid gland and best possible ways to address it? Thanks

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Age/Sex: 20 / Male

Height: 166 cm (measured barefoot)

Weight: 55kg

Parents: Father 168 cm, mother 162 cm

Medical conditions/medications: None [edit if different]

I'm trying to find out if I could still be growing. I have a beard that isn't fully filled in. My mid-parental estimate is about 171 cm, so I'm below it.

Questions for endocrinologists:

Is it still worth getting evaluated at 20?

Is a bone-age X-ray of the left hand and wrist enough to tell if my plates are open, or do I need hormone tests too (testosterone, IGF-1, thyroid)?

If my plates are still open, is there any legitimate treatment, or is it only watch and wait?

Should I see an endocrinologist directly or start with a GP?

I'm not interested in supplements or "height increase" products, just a proper medical opinion.

Thank you!

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Hi everyone, I’m 30 and getting married soon, and I’m honestly feeling very scared and stressed about my periods and fertility.

I’ve had PCOD for around 10 years, but my periods were mostly regular (around 30 days). Four months ago, I was diagnosed with hypothyroidism and started 75 mcg medication. My thyroid is now normal.

For the last 3 months, my cycles were around 34–36 days, but this month I missed my period. My thyroid is still normal, but my prolactin came back at 32.2.

I’m really worried that the high prolactin is causing my delayed period and may affect my fertility. 😔

Has anyone been through something similar with PCOD, thyroid and high prolactin? Please share your experience or advice. I’m really anxious and would be so grateful for some reassurance. ❤️