r/endocrinology

I am 18 female - 5'6¾"

• Currently diagnosed with autoimmune thyroiditis, hypothyroidism, PCOS

Anti-TPO 393 of last December with a thyroid 2x the regular size. Now on 75 mcg of levothyroxine + birth control (Nikki) - starting this Sunday due to it being delayed because of testing.

Follicular Phase Testing (June 30th, 2026)

Bioavailable Testosterone Panel, Peds and Females - 27.4 ng/dL

Sex-binding Hormone - 20 nmol/L

Testosterone females and peds, LCMS - 46.3 ng/dL

Hemoglobin A1C - 5.5%

Estimated Average Glucose - 111 mg/dL

17-Hydroxyprogesterone - 307.7 ng/dL

Estradiol - 80 pg/mL

Macroprolactin -

Prolactin, Total Serum - 52.3

Prolactin, Unprecipitated, Serum - 44

Percent - 16

Prolactin (most recently) - 43.5 NG/ML (Jan 29th 2026)

ACTH Stimulation Test (Luteal) (August 19th, 2026)

Baseline Cortisol - 25.5 ug/dl

Cortisol 30 - 24.9 ug/dl

Cortisol 60 min - 29.5 ug/dl

MRI Pituitary - Clear, pituitary stalk normal (unevaluated pineal cyst 6mm)

Last checked September 18th 2025

Irregular period, painful period, hair thinning, dry skin, thin nails, brain fog, weight gain, joint pain, depression, mottled skin (upper arms and thighs) - there are other symptoms that I'm having issues recalling currently.

Hey folks!

Not looking for medical advice, but seeing if anyone else has had similar symptoms, my doctor think it's possible Pheochromocytoma due to my high blood pressure 175/88.

For the past 10 months, I've been experiencing "episodes" that last from 5 minutes to 2 hours. These episodes have gone from every few days, do multiple times daily.

How I feel during an episode:
- It feels like my heart "skips" a beat or "thuds". I jolt forwards and my breathing becomes really shallow.

- My face becomes really hot.
- Arms feel really weak/heavy.
- Cold rush down my legs.
- Feel clammy/about to pass out.
- Excessive sweating.
- NO headaches/chest pain.

Would love to hear some of y'all's insights and maybe it could be something different.

Feel free to ask any questions!

I have multiple thyroid nodules all tirads 2 doctor said nothing suspicious while doing usg.. said all are benign he seemed very confident. One nodule is slightly bigger but tr2. But on the report at bottom written advice fnac. I am confused now. I knew tr2 doesn't need fnac. Please help everyone.

So I just got my panel done and my test was 340 which they said was within the 10th percentile and they referred me to an endocrinologist and said to get my blood done again in 4 weeks. What I’m mainly wondering is what can I expect if I do get prescribed, my main issues have been low libido(I have a gf and I’m not able to perform sometimes, or keep it up for a long time) tiredness even when sleeping and eating good and my baseline emotion is like slightly before content so I’m almost always just a bit sad if I’m not doing anything. If anyone had similar symptoms or age I’d love to know how it affected you. Also one more thing they said I have high cholesterol so I’m not sure if that would cause any extra issues with my health or getting it initially prescribed.

EDIT: I’m very active I weigh 160 at 5’8 I workout 6 times a week and do 700 cals worth of cardio everytime I go to the gym, my iron and neutrophil were low but everything else was normal

Hi everyone,

I’m currently recovering from hypothalamic amenorrhea and wanted to ask about something that has been worrying me.

I lost my period for a while, and after increasing my food intake and reducing exercise, my cycles started coming back. I’ve now had several periods again, and in my most recent cycle I had a clear LH surge and an ultrasound showing free fluid consistent with ovulation. I’m really happy that my body seems to be starting to function again.
However, I’ve noticed two things that I’m wondering could be connected to HA recovery:

1. Low fT3 and fT4 with normal TSH
My thyroid results have changed over time:
First blood test: fT3/fT4 were still at the lower end of the normal range
Second test: fT4 7.9, fT3 1.8
Most recent test: fT4 6.8, fT3 1.7
TSH: 1.92 → 1.48 → 1.65 (always normal)
I’m not taking any medication.
My gynecologist told me to have my thyroid checked again. I’m wondering whether low fT3/fT4 with a normal TSH can happen during HA, stress or recovery from low energy availability.

2. Very short luteal phase
In my most recent cycle, I had an LH peak around August 9th and an ultrasound shortly afterwards showed signs that ovulation had occurred. However, I started what appears to be my normal period only around August 14/15, which would make the luteal phase extremely short if the ovulation timing is correct.

Could this also be related to HA recovery or low thyroid hormones?

Has anyone experienced low fT3/fT4 with normal TSH and/or a short luteal phase during HA recovery? Did things improve as your recovery progressed?

I’d really appreciate hearing about your experiences.

Tenho 20 anos e queria saber se alguém já passou por algo parecido ou consegue me orientar sobre o que investigar.
De um tempo para cá, percebi uma queda bem grande na minha libido. Estou praticamente sem vontade de ter relações ou me masturbar, e também não acordo mais com ereção como acontecia antes. Quando acontece, é bem raro.
Além disso, tenho me sentido bastante desanimado, com pouca disposição e uma sensação de que não estou sendo eu mesmo. O que mais me preocupa é a combinação da falta de libido com a diminuição das ereções matinais, porque antes isso era algo normal para mim.
Por isso comecei a suspeitar de testosterona baixa, mas não sei se esses sintomas necessariamente significam isso.
Alguém que tenha experiência com testosterona baixa ou tenha passado por algo parecido poderia me dizer:
Quais exames vocês fizeram para investigar?

Qual era o nível de testosterona?

Existem outras causas comuns para esses sintomas além de testosterona baixa?

Vale a pena procurar um endocrinologista ou urologista?

Pretendo marcar uma consulta e fazer uma investigação adequada, mas queria ouvir experiências de outras pessoas antes.

My endo is working up my labs to explore possible Conn's Syndrome. I'm trying to wrap my head around what life with Conn's would be like. I see a lot of videos on what it is but very little about what it's like to live with this condition. I have undetectable renin which of course throws my ARR off.

CT Scan with no contrast came back clear. My endo is leaning towards bilateral Conn's Syndrome.

Thanks in advance. I look forward to hearing from you!

Hi everyone, I need help fixing it.

Im at 13-15% bodyfat yet my T level is 10nmol/L and my E2 is 52pg/ml

Lab ranges:

E2 say that it needs to be <56
I

Hello community. I am a 31 M, who exercise regularly (3-4 x/week) and try to eat healthy with good amount of protein, fats and carbs. For the past few months, I have been experiencing fatigue, muscle weakness, almost zero libido, my morning wood is also a rare event and I cannot sustain my erections. I don’t have energy to perform in the gym as well, it is becoming hard to lift the same weights i used to lift easily. So I got my hormones checked recently, and these are the results:

DHEAS: 8.61 µmol/L — Reference: 4.34–12.2 µmol/L
DHEAS: 3168 µg/L — Reference: 1597–4490µg/L
SHBG: 21.7 nmol/L — Reference: 18.3–54.1 nmol/L
Free Testosterone: 152 pmol/L — Reference: 174–729 pmol/L ↓
Total Testosterone: 6.41 nmol/L — Reference: 8.64–29.0 nmol/L ↓
Total Testosterone: 1.8 µg/L — Reference: 2.49–8.36 µg/L ↓
Free Androgen Index (FAI): 29.5 — Reference: 35.0–92.6 ↓
FSH: 3.0 IU/L — Reference: 1.5–12.4 IU/L
LH: 3.0 IU/L — Reference: 1.7–8.6 IU/L
LH/FSH Ratio: 1.0 — Male reference: not established
Prolactin: 121 mIU/L — Reference: 86–324 mIU/L
Estradiol: 52.6 pmol/L — Reference: 41.4–159 pmol/L
Estradiol: 14.4 pg/mL — Reference: 11.3–43.2 pg/mL

My free and total testosterone are very low. It’s very difficult to get an appointment of an endocrinologist where I live, the waiting time is 3-4 months. What is going on with my hormones? Did anyone experienced something like this? And how did you fix it?

I am 16 year 10 months old male... 5 4 height and my bone age is 17 (got it a month ago) it was evaluated by an endocrinologist..he checked my left wrist x ray.... He said 2 inches may be possible?? Is it true even ? Online it's showing less than 1 cm and somewhere written 1.5 inch what is the truth...

Can I be 5 6 barefoot ?

For context: I have a bit of bad posture , I can fit my whole hand through my back arch when standing against wall., and have a neck bump thingy (basically my ear hole is forward than my shoulder )

Also knee , spine , and shin (leg) growth plates close a bit later.....?

My testosterone is 290 ng/dl and LH is 2.05 if that helps ...

Also is being 5 4 really that bad, like in dating and all ? I'm really insecure and scared....

I want to go to Uk US germany AUS for masters and all but I'm now scared of bullying ....

Father 5 6 and mother 4 11. And brother 5 9..

I can give image of x ray if you want (the x ray itself is a bit blurry)

Hi, I’m hoping someone who has experienced something similar can offer some advice.
We found out in mid-July that my son’s prolactin level was 1,444 mIU/L. His testosterone was also above the normal range. He has been experiencing hair loss but I didn’t notice and still don’t but he says hair are coming off in chunk, and had a pressure like headache that lasted for around three days, although thankfully he hasn’t had another headache like that since.
He has been referred to endocrinology, but his appointment is not until October. I’m worried because it feels like a long time to wait without knowing what is causing these results.
The endocrinologist requested repeat blood tests, including prolactin, testosterone and some other hormone tests. However, our GP removed several of them because they had already been done around a month earlier. I don’t understand why they were removed when the endocrinologist specifically requested them. I thought repeating the tests would confirm whether the levels are still high and whether anything has changed.
He has also been asked to have a testicular ultrasound, which has worried me even more. Has anyone else with high testosterone been sent for a testicular ultrasound? What are doctors usually checking for?
He may also need a pituitary MRI with gadolinium contrast. I’m very anxious about this because a family friend became seriously unwell after having contrast for an MRI. I understand that everyone is different, but it has frightened me.
Does anyone know whether contrast is always necessary to detect a small pituitary tumour, or whether a dedicated non contrast pituitary MRI could be done first? Are certain types of gadolinium considered safer, and should kidney function be checked before it is given?
I would also like to know whether prolactin should be repeated early in the morning after resting, and whether macroprolactin, LH, FSH, SHBG, thyroid function and the other pituitary hormones should be checked.
Is it normal to wait until October with a prolactin result of 1,444 mIU/L? Would it be reasonable for me to contact gp and ask them to reinstate the requested blood tests or consider seeing him sooner?
I have also read about supplements such as vitamin B6 and vitamin E possibly helping with prolactin. I’m not planning to give him anything without checking first because I don’t want to affect his results or interfere with finding the cause, but I would be interested to hear whether anyone was advised to take anything while waiting.
I’m not asking for a diagnosis or trying to replace medical advice. I’m just a worried mum trying to understand what should happen next, and I would really appreciate hearing from anyone who has been through something similar.

36f. Smoker (yeah, I know). Already diagnosed with Fibromyalgia, Adenomyosis, Achalasia and potential PCOS. 5ft6, weight has gone up recently to approximately 13st. Long term plantar fasciitis, leg pain, arm pain, insomnia. Extreme heavy periods (from age of 9, always been irregular and heavy. Periods can last 2 days or much longer, longest lasting 6 months. Constantly flooding). Recently lost my dad to renal cancer, absolutely heartbroken. On waitlist for pain psychologist due to Fibromyalgia pain.

I am being referred to endocrinology. Here is what my referral says:

Please provide as much relevant clinical information as possible to assist with the interpretation of the referral and images:

Patient had FAI bloods and TV USS to investigate for PCOS as was struggling with weight gain and cystic acne for past 6/12

TV USS: reported as unremarkable

High testosterone 3.1, lab added further bloods to investigate for CAH/ androgen secreting lesion

Elevated androstenedione 13.6

17-alphahydrocxyprogesterone 5.5

Fhx: Renal carcinoma – Dad

Urgent referral to endocrinology

Urgent US KUB due to Fhx

- should I be worried? I'm a single parent to two neurodiverse children. My dad's medical history being mentioned has really got me on edge about what they are looking for here.

If anyone can help me make sense of this, I would appreciate it. Just trying to put my stupid curious mind at rest.

Hey everyone. Have been on start for just over two months. Started with estradiol of 12, and total test of 320.

Dr suggested we try out a round of TRT to see how I feel. TBH I don’t feel much different. Still low mood, libido, and fatigue.

Ran labs Monday and came back with high SHBG at 60. A year ago I was 40.

I assumed my free test would come back low, just got it and it’s actually high free is 156 and total is 977. The blood was drawn the day I was due for a shot but hadn’t taken it yet.

I take every Monday and Thurs night, this was on Monday morning. I have been taking 60mg twice a week.

Can anyone shed any light on the results? I’m still waiting on estradiol