u/TeaTimeAt4

Hi, I usually have a 25-26 hour cycle, but for the past week I have only been able to sleep once every two days. I have been holiday planning and I suppose it has got my blood pumping as I have been planning and suddenly realise I have not slept for 24 hours. I haven’t been getting tired until the 30-35th hour awake. I am also missing meals when I lose track of time and forget to eat.

Has anyone else experienced such a sudden change in sleep cycle length? Any advice on how to not do that?
And before anyone asks, no I am not bipolar, yes I have autism.

POTSies with hypermobility, which medications have you tried and which helped? I’ll go first.

While awaiting diagnosis, GP had me try bisoprolol, but the POTS specialist thinks that made my symptoms worse :(

POTS specialist had me try midodrine (I couldn’t tolerate the scalp tingling) and pyridostigmine, which helps but I’m only on the lowest dose.

Non-POTS specialist cardio wants me to try ivabradine and fludrocortisone, but hopefully I can convince her to switch fludrocortisone for desmopressin. I don’t know if this will help since I don’t have particularly low blood volume, but I’m scared to death of steroids, so if it doesn’t help, I just want her to accept that fluid retention agents aren’t the way to go.

What I’m really interested in is alternate vasoconstrictors, and the safest seem to be noradrenaline reuptake inhibitors like bupropion or methylphenidate.