u/Total-Reference7212

I was reading some older studies that bascially say that dysphoria is mainly related to body self processing networks, how does estrogen link into this.

I was reading some studies done in the past 10 years that basically say homosexuality is linked to less sexually dimorphic ( or partially reversed ) patterns of white matter tracts and gender dysphoria is linked to body self processing networks / thicker midline cortex structers, ifof differences, some smaller level of defeminisation ( ftm) or demasculinisation (mtf) when controlling for sexual orientation.

Wondering how does this gel with estradiol or estrogen being a factor in brain masculinisation ? Where does one even look for it. There are barely any opportunities to study the cortical homonculus even in cis folks.

Seems like the visible neural signature for being trans is quite similar to both trans men and women.

I was also reading some studies basically saying that synesthesia is extremely common in trans people even controlling for autistic traits, wonder if we are just literally experiencing our bodies differently than other people

https://www.frontiersin.org/journals/child-and-adolescent-psychiatry/articles/10.3389/frcha.2024.1356802/full

academic.oup.com
u/Total-Reference7212 — 1 day ago

Hyper focus, sensitivity to stress, noises, wired and tired all the time, ocd tendencies, hence not liking being around people that much due to ease of being overloaded - I wonder if a lot of it can lead to someone getting a higher score on a questionnaire for self assessment ( I know actual clinical assessments are different ).

Slower COMT might be more common in ASD because of the hormonal imbalances it causes / we know from this board and Dr Powers and Co research that it's definitely much more common in trans folks, and probably the reason for the overlap.

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u/Total-Reference7212 — 22 days ago

Not a study related to trans people but thought it was interesting that that bit of cortex has different responses in male/female study subjects

'We conclude that male genital cortex follows somatotopic organization and that genital reports evoked by cortical stimulation differ between males and females. Genital cortex stimulation appears to elicit genital responses in males and leg responses in females.'

academic.oup.com
u/Total-Reference7212 — 26 days ago