Which powers would have the most interesting interactions with drug-use?
The original thought I was having was when reading a fic where Coil eats pie in both timelines because his day is bad enough he needs double-pie and then found myself wondering what happens if Coil does drugs. Genuinely, what happens? Is he intoxicated in both timelines or just the one he (drank/smoked/snorted/huffed) a thing in? Is there any tangible difference which of the two simulation-visions Coil sees he follows through on/if its the 'discarded timeline' or the 'kept timeline'? If he tries to write notes on a subject in both timelines, do sober!Coil and intoxicated!Coil have noticeably different thought-patterns in a way he can notice?
Otherwise, I am curious what happens with Taylor's swarm when she's drunk or high or tripping balls. She offloads physical responses into the bugs and has nominal omni-multitasking: what does she do idly, not paying attention? What happens if she tries to do a thing with the swarm she does when sober, except now she's not? What does that look like in any tangible sense?
...Look, I want to smash my special interests together. Drugs and parahuman power-system antics, let's go! Which parahumans should we give drugs and why?