New at this and I'm trying to understand if it's possible to get a script for say 4mg per month but only actually use 0.5mg per injection (so kerping the vial in the fridge for 4mo. Any guidance is massively appreciated.
I'm hoping to reproduce a pilot study that was published this spring in the journal Cell Metabolism called 'Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism'.
In combination with Hyaluronic Acid injections, their findings suggested a weight-loss independent 17% increase in knee cartilage thickness on MRI scans over 42 weeks. I'll start by saying this is an extremely early stage test with results that could easily be non-reproducible in me, a non-mouse. That said, I have nothing to lose but a few pounds. I could use some advice about sourcing (below).
I am a 200lb 6'2" male with early stage osteoarthritis in my knees and am currently receiving hyaluronic acid injections for that. I'll mention here that I have identified cardiovascular risk factors in case that supports a health insurance angle. I'm insured through Anthem Blue Cross/Blue Shield.
I'm completely new to the microdosing concept, but my ideal would be to receive a script for say 4mg weekly, store the medication and actually take 0.5mg weekly in order to save some cash. My general doctor is fine with prescribing it but may not want to fake the dose in the way I'm describing. I'm not really thrilled about sourcing from an online compounding company but I suppose I could if it were reputable. It has to be Semaglutide at .5mg and injectable.
All things considered, how should I go forward securing semaglutide doses? Any help is appreciated.
​
My 14-year-old daughter and I land at Shannon Wed for four nights based in the countryside outside Gort. I've been, she hasn't.
I've read some itineraries here and tried to keep our visit from turning into a nonstop driving tour. We're timed around the Galway International Arts Festival, which is what the two late evenings are. Here's the plan:
Wednesday: Land at Shannon late morning and settle in at the house. Later an evening show in Galway. We'd drive back after, probably on the road around 10:30pm.
Thursday: Free morning then a lot ng during to the famine village walk at the Lost Valley near Louisburgh in the early afternoon. I'm not sure about the route home. Will either go straight back via Westport or the longer Doolough/Killary loop if to see more.
Friday: Galway food tour in the morning and then afternoon exoring around the city. Early dinner then a 9:30pm event. This is the late one. We won't be on the road home until 11pm or later
Saturday: we're doing a guided cliff walk at Doolin at 10:00am then Burren in the afternoon (Poulnabrone and a 4:30pm hawk walk at Aillwee). We plan to have dinner in Kinvara before a short trip home
Sunday: We plan to be out the door a little after 6:00am for a 9:30am flight out of Shannon
My main question is the night driving. I'm a confident driver but I've never driven in Ireland, and I'm aware that unlit rural roads at midnight are a different animal than they are at noon. Coming back from Galway we have two options - take the M18 down and finish on the R460 out of Gort, or take the N67 coast road and finish on the L4508 out of Kinvara. Either way we're only on the small road for about 10 minutes but it'll be in the dark, on the unfamiliar side of the road.
Which would you take at 11pm: The motorway route with the regional road at the end, or the coast road with the L road at the end? And is there anything I should know beyond slow down and watch for walkers and livestock? Should I just not?
Is Thursday too much? The Lost Valley is roughly 2 hours each way from us. The walk itself is the thing my daughter is most excited about, but I'm torn on whether the scenic loop home is worth it or whether we should just take the direct road and get dinner at a reasonable hour.
Appreciate any local knowledge. You've helped me through old posts by others already.
Trying to decide if I should check a large bag for us to share. I'm not concerned about the money, just the hassle. What do you think?
In a couple of weeks I'm taking my daughter on her first international trip: 4 days in London via United, then on to Galway Ireland via Aer Lingus for another 4 days. All lodging has a washer/dryer.
For baggage I'm usually in the "fast and light" camp but I am not her. The default, common denominator baggage limit without checking is: one personal item under the seat and a roller bag up to 9 in x 14 in x 22 in (23 cm x 35 cm x 56 cm) up to 22lb/10kg.
I am using the Demaree method to limit my hive count and prevent swarming. The trouble is, I don't really have any open frames to offer the queens (lots of capped old honey in deep frames). Two questions:
Can I extract the honey from the frames in order to give the queen foundation to lay in? I'm pretty sure this is an easy yes but want to confirm
With that honey (and keep in mind it's been exposed to miticides, was overwintered partially as nectar and may have fermented a little, etc) should I store it and feed it back in fall winter, call it a loss, gently heat it and then feed it back to knock back any alcohol?
Any input is appreciated