403 pg/mL: paraesthesia, tinnitus, MTHFR, GLP-1 use
Hello, all-- so glad to have found this sub!
Around 3 months ago, I developed tinnitus, cranial nerve irritation, numbness, jaw pain, and electric shocks throughout my body that get worse at night. I had been on a low dose of compounded GLP-1 for over a year, resulting in a 15-pound weight loss. I have MTHFR, if that makes a difference.
The paraesthesia apparently can be a side effect of GLP-1s, so I stopped taking them about a month ago. I also learned that they were *not* compounded with b vitamins. Early on, when I was trying to figure out why I was experiencing these symptoms, I upped my GLP-1 dose, and the electrical shocks were at their worst that first night.
I was tested for vitamin B12, and it's at 403 pg/mL. Since being tested, I started taking sublingual Hydroxocobalamin B12 and an oral benfotiamine form of thiamine. My symptoms are still present but have lessened, and I'm not sure whether that's due to supplementation or to stopping GLP-1.
Has anyone else dealt with this combo of symptoms and factors? I am wondering if I would benefit from B12 injections. Like others, my doctor is convinced that my B12 is adequate, so this is not a conversation I can have with them.
Is there a downside to injecting B12? Will I know right away if the injections are benefiting me?