
u/barrel_master

New uranium mines in Saskatchewan could become one of the world’s largest
youtube.comKyiv Post: Fire Point Boss Says Home-Grown Ballistic Missile Interceptor May Be Operational by Mid-2027
kyivpost.comCNN Live updates: Iran demands concessions from US as it nears Strait of Hormuz deal with Oman
State media published the list of requirements from Zolghadr, the secretary of the Supreme National Security Council. The list includes measures such as lifting the US naval blockade, withdrawing military forces and permanently ending the war.
Zolghadr also calls for the US to compensate Iran for damages caused by the conflict and release frozen Iranian assets.
“These are the demands of the Iranian people, which they have loudly proclaimed during 160 days of steadfast presence in the field and in the streets,” the politician said.
“Until America corrects its behavior, the Strait of Hormuz will not be reopened,” his statement read.
Earlier on Saturday, Iran’s Foreign Minister Abbas Araghchi said that Iran is “very close” to reaching a deal with Oman on managing the Strait of Hormuz.
But he cautioned that the reopening of the strait was “subject to other conditions,” including the US making amends for what he said was a violation of the memorandum of understanding agreed between the two countries in June.
Follow the Money All the Way to Carney's Canada
bloomberg.comMiriam Merad at ARDD2025: Targeting inflammaging to enhance health span
youtube.comAlessandra Zonari at ARDD2025: Introducing OS-01: Targeting cellular senescence to optimize skin
youtube.comThe Hidden Reason This Edmonton Park Cost $134 Million
youtube.comMIT: Injectable “satellite livers” could offer an alternative to liver transplantation
news.mit.eduAlberta premier welcomes massive Meta data centre twice the size of Central Park | Power & Politics
youtube.comHow fundraising is going so far for third-party advertisers in Alberta's referendum campaign | CBC News
cbc.caNational Bank of Canada: Housing affordability improves in 2026Q1, extending two years of progress
nbc.caThe drone turning the tide of the Ukraine war | War On Tape | Daily Mail
youtube.comSaskatchewan could hold the key to Canada’s foreign trade goals
youtube.comThe Globe and Mail: A reality check on Alberta separatism
youtube.comGLP-1 drug ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism
Apparently the study was only done in 20 people but it's still encouraging.
Abstract
Metabolic disorders have been recognized as a major contributor to the occurrence and progression of osteoarthritis (OA). Identifying novel therapeutic agents to ameliorate the progression of OA with metabolic disorder is crucial. In this study, we demonstrate that ... a glucagon-like peptide-1 receptor (GLP-1R) agonist, exhibits strong chondroprotective effects in an OA mouse model with obesity, as evidenced by reduced pathological changes, including cartilage degeneration, osteophyte formation, synovial lesion, and pain sensitivity. A randomized pilot clinical study (ChiCTR2200066291) further supports these findings. By designing a precise diet-controlled setting to rule out the effect of appetite suppression and weight loss induced by SG, we demonstrate a weight loss-independent mechanism. Through regulating the "GLP-1R-AMPK-PFKFB3" axis, the SG reprograms chondrocyte metabolism profile from glycolysis to oxidative phosphorylation under inflammatory conditions, resulting in cartilage restoration.
Ukraine regains momentum as Russia suffers battlefield losses | DW News
Shareable video from DW News going over how Ukraine is winning.
Iran on the verge of economic asphyxiation -- rare footage from Tehran • FRANCE 24 English
A reliable and shareable France 24 video about how things are in Iran. I hope the people of Iran can one day be free of this terrible regime.