Starting Wegovy for PMOS/insulin resistance (feeling anxious and would love to hear your experiences)
I was diagnosed with PCOS/PMOS in 2019.
I’m 28 years old, 152 cm (5’0”) and 64 kg (141 lb), and I’ve struggled with my weight pretty much my whole life. Losing weight has always been extremely difficult for me. I’ve tried many diets and even tracked my calories consistently for years, but the scale barely moves.
For years, my gynecologist basically prescribed me the pill and told me to try to lose weight. I’ve also tried metformin multiple times, but the stomach issues were always bad enough that I had to stop.
PMOS has affected me beyond my weight. I often feel extremely tired after eating because my blood sugar was crashing, which makes it difficult to concentrate and work. I’ve also had irregular periods and ovarian cysts. Hair under my chin. I also had PMDD at the start of my diagnosis.
I finally decided to see an endocrinologist. She ordered comprehensive blood tests and an ultrasound. Pretty much everything came back normal except for my HOMA-IR, which was high and indicated insulin resistance.
We tried metformin one more time, but my stomach still couldn’t tolerate it. My endocrinologist then prescribed Wegovy 0.25 mg, and I’ve now been on it for 5 days.
I’m hopeful, but also pretty anxious. I’m scared it won’t work for me or that the side effects will become too much and I’ll have to stop. After struggling with this for so long, I’m afraid of ending up back at square one.
So far, I’ve had some gas and constipation after breakfast and acid reflux after dinner. It’s manageable, but I’m wondering if this is just my body adjusting since I’ve only just started.
For those with PCOS/insulin resistance who have taken Wegovy or another GLP-1: did your side effects improve over time, and did the medication help with your insulin resistance symptoms as well as your weight? Did you eventually come off it, or is this something you expect to take long-term?
I know everyone is different and I’ll discuss the medical side with my endocrinologist, but I’d really appreciate hearing your experiences. It would help ease some of my anxiety about starting.
TL;DR: PMOS + insulin resistance, couldn’t tolerate metformin, and just started Wegovy 0.25 mg 5 days ago. I’m having mild gas, constipation, and acid reflux and I’m anxious about whether it’ll work, whether the side effects get better, and whether I’ll need it long-term. Would love to hear your experiences!