r/Semaglutide

Hi all,

i'm 2 months in. Taking tablet form (7mg per day). Starting weight at the beginning of September was just on 108kg - now I'm at 101kg.

i've upped my exercise - trying to move more daily (semi-sedentary desk office job!), and i am cycling 100kms per week (3 days a week for 1-2 hours).

first month i felt very 'agitated' most of the time - but that lessened, 2nd month felt anxious a lot - sometimes real panic mode - but that too has passed.

ive always been a bad eater - and im trying better to get regular good foods. Still drinking too much beer - but working on that one too. High stress job and a very poor sleeper!

I want to get back to my pre-covid weight / activity of 80kg's - fit and active before its too late.

Has anyone had nocturnal incontinence while taking Semaglutide? I also have Crohn’s Disease and take Humira but since being on Sema, I’ve had quite a few “accidents” in the night where I literally don’t wake up but have messed the sheets. :( I’m now keeping a food journal to try and identify the culprits but it’s completely random and unpredictable. Scared to sleep over with my Partner.

How often do you weigh yourself? Trying not to get frustrated by fluctuations on the scale but it’s hard.

If you're paying NovoCare cash and stuck between the shot and the pill, the gap at the top doses ($299 vs $349 a month) undersells how the first few months play out, because the two step up on different price ladders.

Following the label's dose schedule, one fill a month:

Pill: 1.5 mg $149, 4 mg $199, 9 mg $299, then 25 mg at $299. First 6 months: $1,544.

Pen, new patient: 0.25 mg and 0.5 mg at $199 each (the intro price, 2 fills), then 1 mg, 1.7 mg and 2.4 mg at $349. First 6 months: $1,794.

So about $250 apart over six months, then $50 a month after that if you'd stay on 2.4 mg, or $100 a month if your prescriber takes you to Wegovy HD 7.2 mg ($399).

The date to watch: NovoCare says the $199 pen intro runs through Dec 31, 2026. Without it the starter pens are $349 like the rest, and the six-month gap grows to $550. The page doesn't put an end date on the pill prices.

A couple of things apply to both. Self-pay doesn't count toward your insurance deductible or out-of-pocket max. And the self-pay prices are open to people on government plans too. Only the $25 savings card shuts them out. If you're on Part D, the Medicare GLP-1 Bridge ($50 a month, if you qualify) beats both.

Real life won't follow the table exactly. Plenty of people stay on a dose longer than a month, which shifts the math. Pill or shot is a call for you and your prescriber. This is only the cost side.

Source: NovoCare Wegovy self-pay offer page and the Wegovy prescribing information (dosing tables), checked Oct 5, 2026. Not medical advice.

I took my first semaglutide injection last night using a syringe. Before this, I had been taking the oral form of semaglutide for about a month at 1 mg. Since I wasn’t seeing much progress with the pills, I decided to increase my dose when I placed my next order.

When the medication arrived, the instructions told me to take 1.4 mg. I remember thinking that seemed like a lot. I know for a fact that I had listed my previous medication as the oral form of semaglutide , but I went ahead and took the injection anyway.

I took the shot around 10 PM last night. About an hour later, I started feeling nauseous while I was asleep. I woke up and vomited for the first time around 4 AM. Then I vomited again at 6:30, 6:45, 7:00, 7:30, 8:00, 8:30, and continued vomiting frequently after that.

I’ve already decided that I will never take the injectable form again. I’m just desperate to know how long this is going to last. It has been almost 16 hours since my injection, and everything I’m reading online says that nausea can last for several days.
Since my nausea started so quickly after the injection, I’m really hoping that maybe I’ll start feeling better sooner. Has anyone experienced something similar and had the nausea/vomiting improve relatively quickly?

Please share some hopeful experiences if you have them. I could really use some encouragement right now. ❤️