u/madcook1 — reddlx

Ivermectin improves fat digestion

I'm currently testing Ivermectin as part of a treatment against a tick borne co-infection (Babesia and Bartonella), and noted that it improves my fat digestion a lot. Currently I'm taking 500mg TUDCA per meal, which works fine for around ~250-300gr of fatty beef. If I go over it, I get inflammation that causes MMP-9 activation which makes my hands and skin very dry (sometimes so dry they crack and bleed).

Just took 12mg yesterday, and already noted improved fat digestion and very very smooth skin the next day. AI said Ivermectin is a potent FXR ligand that somehow maintains bile acid homeostasis:

https://pubmed.ncbi.nlm.nih.gov/23728580/

Did anybody experience the same with Ivermectin? I found that reaction very odd (but welcoming) and wondered about it.

u/madcook1 — 18 hours ago

▲ 15 r/Lyme

Strong reaction when improving circulation with Tadalafil

In my previous post I asked about using Tadalafil to improve circulation: https://old.reddit.com/r/Lyme/comments/1t96j0c/improving_circulation_with_tadalafil/

I'm currently on a regimen against Babesia and partly Bartonella (Tafenoquine, Malarone, Azithromycin, Methyleneblue, Lumbrokinase) and after around 3 months I didn't feel any more herx from the medication. Because I always have cold feet and hands, I wondered if the medication actually hits all the places. Then I tested Tadalafil (cialis) with 1.25mg (1/4 of a 5mg tablet) to improve circulation, which started a lot of continous herx. It was bearable, but felt like the herxes I had when starting the medication.

Then after 3-4 days, I added 2.5mg on top of the 1.25mg, and boy, that opened herx hell. I suddenly had flare ups I had many many years ago, even symptoms I forgot I had. The herx "intensity" was a lot worse then I have ever experienced being on the meds (this is the second round).

Before Tadalafil, I tried Pycnogenol which also improves circulation, and I was not sure if the symptoms I got from it was from side-effects or herx. Now I know, it was herxes. If I had to guess on herx severity, I'd say 100mg Pycnogenol equals around 2.5mg Tadalafil.

The Tadalafil is now out of my system, no strong herxes any more from the meds I take. And I'm always walking around 10-15.000 steps a day, and that didn't causes herxes like Pycnogenol/Tadalafil.

In my last round (Tafenoquine, Malarone, Doxycycline, 3-4 months) I had massive improvement after I finished the round, but just 3 weeks later I relapsed. By improving circulation, I might hit all the places where the pathogens hide. At least for me, that seems the missing piece.

reddit.com

u/madcook1 — 7 days ago

▲ 1 r/Lyme

Improving circulation with Tadalafil

I'm currently treating Babesia and thought about adding low dose Tadalafil (which is..cialis) to improve circulation. Tadalafil is a PDE-5 inhibitor which causes vasodilation. I always have cold hands and feet, and wonder how much of the Babesia is actually hit when the blood flow is impaired.

I have some experience with Pycnogenol which should also improve circulation, but I couldn't find out if the reaction from it is a Herx or side-effect.

Any one used that or has experience?

reddit.com

u/madcook1 — 12 days ago

▲ 2 r/tinnitus

In my original post I claimed that my tinnitus was caused by my monitor, and I want to backup my claim with some measurements I did with a spectrum analyzer.

Here you see the different emissions spectras measured with a tinySA and a 50cm telescopic antenna infront of the monitor with around 40-50cm distance: https://imgur.com/a/15WFCvQ

In the first image you see the 120Hz DisplayPort connection radiating off the Gigabyte M27UA (non-TCO) monitor. Switching to a 60Hz HDMI connection reduces the frequency of the signal, but it's still there.

I then tried out a Dell P2725QE monitor that is TCO certified, meaning it has strict electromagnetic emission limits, and the signal from the DisplayPort or HDMI connection is completly gone. Note that the 16MHz signal you see in all spectras is coming from my laptop.

With the Dell P2725QE, I have no tinnitus when I sit infront of the monitor. When I switch the monitors back to the Gigabyte M27UA, the tinnitus instantly starts. Way worse with DisplayPort 120Hz, but even HDMI 60Hz does start the tinnitus.

u/madcook1 — 24 days ago