u/mkp0002

Hey guys. I’m feeling extremely anxious today regarding my dad and could really use some support.

Past History

My dad is 55M and was diagnosed with FSGS in 2021, with a creatinine of 1.4. He also has hypertension and diabetes.

His creatinine slowly climbed to around 2.4 by September 2025. (1.0 In 4 Years)

From September 2025 to April 2026, we didn’t have any tests done.

On April 20–25, 2026, he had an upper GI bleed. His creatinine jumped from 2.7 (taken at another lab) to 3.9 overnight, which we were told was likely related to the GI bleed.

After the bleed, his creatinine stayed around 4.1 from April through July. We were hoping it would gradually come down over time.

But today, his creatinine came back at 5.9, and I’ve been extremely anxious since then.

We repeated the test later today, and it was 5.6.

His doctor has also started discussing a transplant, which has made everything feel even more stressful.

He has no visible symptoms. No swelling, no tiredness, no shortness of breath — he feels completely normal.

The doctor hasn't advised any lifestyle changes since he is already under 4g Salt and low Pottasium diet.

I never expected his creatinine to jump this quickly over such a short period.

I have a few questions and would really appreciate hearing from people who have been through something similar:

1. Can dehydration cause a sudden jump in creatinine like this?

2. Is it really possible for creatinine to increase this quickly?

3. At what creatinine level or eGFR did you start dialysis or begin the transplant process?

4. Can Creatinine be 5.9 in Morning and Drop to 5 6 in just 6hrs?

I know everyone’s situation is different, but hearing about other people’s experiences would really help me understand what we might be facing.

Thanks in advance.

Dad 56M, Diagnosed with CKD (Secondary FSGS)

So. In the month of September 2025 the Creatinine was at 2.5 and Sugar was pretty high with Hba1c around 9.7 (Creatinine was 1.8 in 2022, 2.2 in 2024)

Fast forward to April, He had Toothache and had taken NSAID.

On April 19 he felt weakness along with Tarry Stool. We ignored it thinking it might be dehydration.

On April 21 after Blood tests. The Results (Hb 10, Creatine 2.8 Urea 154) The doctor Indicated possible GI bleed.

On April 22 after another Blood Test. The results (Hb 6.2, Creat 3.7 Urea 140) - Overnight Drop

Admitted him immediately and had Endoscopy done. The Upper GI bleed was caused due to NSAID. No active bleeding.

On April 26 After discharge his Hb numbers have gotten better

On May 4, Testing with another lab we got creatinine of 3.8 with hb 9.1

And on May 19, his hb is at 9.6 but the Creatinine is still at 4.1

(Urea, Uric Acid and all other vitals are in normal range)

My question is, Is 4.1 his new baseline or does it usually take month or two to come down since he had overnight drop.

Does low hb lead to high creatinine numbers?