Fragrance-free luxury moisturizer recommendations for 60+ skin, but also safe around a very sensitive toddler?

Looking for some help finding a moisturizer for my MIL. She’s 60+, very serious about skincare/wrinkles, and normally uses expensive/high-end products.

The problem is that her fragranced skincare triggers MCAS reactions for me and my daughter. She also cuddles our 14-month-old granddaughter cheek-to-cheek, kisses her, etc., and afterward I can actually smell her skincare on my daughter, so there’s definitely product transfer. Our daughter is extremely sensitive/reactive as well.

I’m looking for something:

  • Completely fragrance-free (including essential oils)
  • With ingredients I wouldn’t worry about transferring onto a toddler’s skin
  • Great for mature 60+ skin
  • Nice/luxurious enough that someone who loves high-end skincare will actually use it

So far I’m considering Skinfix Barrier+ Triple Lipid-Peptide Cream or Avène Tolérance Control. Any better recommendations?

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u/obllak — 8 days ago

Sequencing.com / bioinformatics review wait time

Has anyone here had their results escalated to sequencing.com’s bioinformatics team for manual review? If so, how long did it actually take to hear back? We were told 3 to 4 days, and we have now been waiting 8 days with no meaningful update.

This is regarding an unexpected, very serious genetic finding in our 14 m/o daughter. The variant was called from 7 out of 36 reads (29 reference reads and 7 alternate reads), which is one of the reasons we desperately want an experienced bioinformatician to look at the raw sequencing data and tell us how confident they are that this is a real constitutional variant.

When we first saw this result, our entire family was devastated. We cried in despair. We barely slept. We have spent the past week frightened, depressed, and obsessively trying to understand what this could mean for our little girl's future.

When you are waiting to find out whether your baby may have a serious genetic condition, every additional day feels unbelievably long.

u/obllak — 9 days ago
▲ 0 r/MSPI

R goat milk

Did anyone’s baby with MSPI/FPIAP failed raw goat milk? I’ve seen plenty of babies react to goat formula or pasteurized goat milk, but I can hardly find any negative experiences with raw goat milk, just success stories.

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u/obllak — 3 months ago
▲ 1 r/MSPI

11.5 month old with FPIAP became unable to tolerate any solids after amoxicillin

My daughter is 11.5 months old. She was a super colicky baby from birth and was diagnosed with FPIAP after we first saw blood in her stool at almost 2 months old. She has been exclusively breastfed since birth.

At 5.5 months we started solids and she struggled (mostly disrupted nights, discomfort, and poor stools) but she was still growing well, meeting milestones early, and stayed around the 80th percentile. The blood had decreased by then, but she never really had normal poop.

At 8 months she was prescribed amoxicillin for an ear infection (10 days). During and after antibiotics she developed severe diarrhea (7–12 stools/day). Ever since the antibiotics, she seems unable to tolerate any food at all. Even tiny amounts (1/4 tsp pre-chewed meat, 1/4 tsp zucchini, etc.) trigger what looks almost like an IBS attack: she strains on the potty for up to an hour with diarrhea and continues straining even after she is emptied out.

She also became much more sensitive overall, with more blood and mucus in stools. I had to heavily restrict my own diet because she started reacting through breastmilk too. Right now I only eat meat + salt, and as long as she is exclusively breastfed she stays relatively stable.

However, she is now down to the 60th percentile and struggling more to maintain weight now that she is extremely mobile and active.

Has anyone seen something like this after antibiotics in an infant with FPIAP?

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u/obllak — 3 months ago

11.5 month old with FPIAP became unable to tolerate any solids after amoxicillin

My daughter is 11.5 months old. She was a super colicky baby from birth and was diagnosed with FPIAP after we first saw blood in her stool at almost 2 months old. She has been exclusively breastfed since birth.

At 5.5 months we started solids and she struggled (mostly disrupted nights, discomfort, and poor stools) but she was still growing well, meeting milestones early, and stayed around the 80th percentile. The blood had decreased by then, but she never really had normal poop.

At 8 months she was prescribed amoxicillin for an ear infection (10 days). During and after antibiotics she developed severe diarrhea (7–12 stools/day). Ever since the antibiotics, she seems unable to tolerate any food at all. Even tiny amounts (1/4 tsp pre-chewed meat, 1/4 tsp zucchini, etc.) trigger what looks almost like an IBS attack: she strains on the potty for up to an hour with diarrhea and continues straining even after she is emptied out.

She also became much more sensitive overall, with more blood and mucus in stools. I had to heavily restrict my own diet because she started reacting through breastmilk too. Right now I only eat meat + salt, and as long as she is exclusively breastfed she stays relatively stable.

However, she is now down to the 60th percentile and struggling more to maintain weight now that she is extremely mobile and active.

Has anyone seen something like this after antibiotics in an infant with FPIAP? What conditions would you consider looking into?

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u/obllak — 3 months ago