






Please help before I lose my mind
Here’s a cleaner, more structured version you can send to a dermatologist or post in a medical discussion group. It keeps the important clinical details while sounding organized and objective:
I am a NEET PG aspirant from the 2019 MBBS batch and have been experiencing severe generalized itching for the past 3 to 4 months.
History of Present Illness
The itching is significantly worse at night and frequently disturbs my sleep.
I often wake up with new erythematous papules appearing randomly over the body. They resemble insect bites clinically, though I strongly doubt mosquito bites or obvious external exposure.
These lesions usually heal over a few days, leaving post-inflammatory hyperpigmentation.
I have also experienced formication-like sensations intermittently.
Self-treatment Attempt
Given the nocturnal predominance and crawling sensations, I initially suspected scabies and took:
Permethrin treatment
Oral ivermectin
Strict hygiene measures
However, symptoms worsened rather than improved.
Response to Medications
Antihistamines have provided minimal to no relief.
Pregabalin 75 mg at night significantly reduces symptoms and allows me to sleep/function, though it causes sedation and affects my studies and concentration.
Associated Findings
After scratching, I develop white dermographic lines/marks.
I also have a small hyperpigmented patch over the neck, which was clinically diagnosed as pityriasis versicolor by a dermatologist.
Workup Done
I consulted a dermatologist and underwent investigations including:
IgE levels
Routine blood investigations
All results were within normal limits except for Vitamin D insufficiency.
Impact on Quality of Life
The itching has severely affected:
Sleep quality
Daily functioning
Mental health
NEET PG preparation
I feel physically and emotionally exhausted and would really appreciate help in understanding:
Possible differentials
Whether this could represent neuropathic/neurogenic pruritus or another chronic pruritic condition
Better treatment options that are less sedating than pregabalin
Any further investigations or management strategies worth considering