r/DIYtk

▲ 0 r/DIYtk

Liquid k to nasal spray

Title, I wanna turn Liquid K from clinic (1000mg/ml) into a nasal spray. can anybody with experience please clarify whether if it’s possible to simply transfer liquid from vial to nasal spray or if any other steps are needed.

Thank you!

reddit.com
u/FightClubIsGoated — 11 hours ago
▲ 3 r/DIYtk

Feeling lost

Been dealing with pretty intense and persistent suicidal ideation and strong symptoms of BPD + anxiety + depression + other stuff (???) for the past few years (starting in early teens). In school right now (undergrad) and don't know how I'm going to survive this next semester without splintering into little pieces to be perfectly honest, like by all rights I should've been admitted last semester... Was going to give DBT a chance soon and get into DIY (S) ket therapy on the side because I've been reading up on the neuroplasticity side effects and I think I could benefit from them a lot as I tend to have a hard time opening up and actually letting positive connections into my life (I've been too mentally blocked for therapy and uncertain of how to implement it successfully I've noticed), have been crashing in the same car for probably almost half my life at this point, and I've noticed I do tend to respond better to spiritual/philosophical exploration (i.e. reading Kierkegaard's works has been a bit helpful to me but I still find it hard to translate into positive changes to my life) so wondering if a dissociative state that would allow me to more fully grasp those ideas would be beneficial in my case.

I read up that K-holes might have a more positive impact than microdosing, so I was thinking I'd stick to a regimen of about 100mg (I weigh 50 kg) administered via nasal spray for 1-2 times a week for the first month or so then transition into a more casual once-a-month schedule that would probably become more sporadic as time goes on and I've reaped the benefits of the initial "catalyst" doses.

Any advice or things I should be aware of before starting? Or things to consider and do to make the most of this period of expanded learning and healing? I've been plagued with very intense thoughts of suicide throughout most of my life, and I would really just like to learn to overcome them through any way possible at this point and become capable of adjusting to a normal human existence without near-constantly breaking down 🙏

EDIT: forgot to add am currently on lamotrigine and sertraline

reddit.com
u/No_Pollution_459 — 3 days ago
▲ 20 r/DIYtk

I am going to use ketamine to treat my autistic burnout.

This was copied from another subreddit after I posted it there, sorry if there's any overexplaining things that was for the other sub.

I have been doing research into ketamine-assisted psychotherapy and while it is not available to me, I think I can just do it myself. It sounds very promising and I honestly don't see any other options. I cannot wait 3+ months for this to sort out on its own. And honestly at this points, I do not care about the risks. That doesn't mean that I wont be careful, I am going to set a routine and follow it. I will keep the dose the same. I will follow the steps that the clinics follow as best as I can on my own.

When you are in burnout your amygdala is constantly stuck in the on position and the connection between your prefrontal cortex and amygdala physically weaken. You completely lose the ability to turn off the amygdala.

In the short term ketamine mutes the signals from the amygdala, finally allowing it to turn off. but that is not the main thing I am interested in. With the right dose, ketamine releases a large amount of glutamate and BDNF which causes the brain to rapidly regrow the neural pathways connecting the amygdala and prefrontal cortex.

The main thing that I am concerned about is the dose. Because I am not getting the medication from a clinic I do not know the purity. and because I will have to snort it, there is only a 35% - 50% bioavailability. The dosage required for getting the glutamate and BDNF release works in an inverted U shape. So taking to little or too much will result in a lesser/no release of the chemicals required. So idk how I can make sure I am taking the correct amount.

Just for some context I am no stranger to ket and I can get, what to my knowledge, is extremely pure stuff.

reddit.com
u/Haunting-Mongoose152 — 7 days ago