Anyone out there have their LP correlated to GLP1, specifically Zepbound? Doc says it’s rare but they are seeing new cases popping up more and more.
Obviously I will stop taking it so we’ll see in about 6-8 weeks if my rashes improve. I sure hope so.
I can’t even begin to start with all the money I’ve spent on products … either over the counter or the ads that come up on my social feeds constantly or the natural remedies people swear by … and nothing has actually helped flatten out or stop the spread of this. I have it on my hands and feet but also patches all over my body. I have a follow up doctor appt soon and I really don’t want to be put on any of these prescriptions because they all seem to have horrible side effects or risks of cancer associated with them. I am currently on Dupixent (for about 6/7 weeks so far) because I actually have eczema and asthma too but I don’t know if it helps with skin LP.
26M, Colombia. I've had this for 2 years and it's worrying me.
Skin: Every time I get a cut or scrape on my legs or feet, instead of healing normally it turns into purple/violet patches that are slightly raised, a bit scaly, and extremely itchy. They take weeks or months to fade and leave the skin very dark (hyperpigmented). Recently I've also started getting a rash between my toes.
Nails: I noticed vertical ridges on almost all my nails, and now I also have small pits in different spots and some horizontal grooves.
Has anyone had something similar? What were you diagnosed with and what worked for you? Photos attached.
I’m officially running out of answers for chronic vulvar + mouth pain and inflammation. Has anyone experienced something like this?
I’m posting because I’ve been dealing with chronic vulvar pain and inflammation for 5 years, along with recurring inflammation/ulcers in my mouth, and I genuinely don’t know where to go from here.
I got these symptoms when I was 28 and I have IBD, but it is currently well controlled, and my doctors don’t think the severity of my vulvar pain can simply be explained by an active GI flare.
My vulvar symptoms include:
Chronic daily burning/pain, often around 5–7/10
Skin peeling/sloughing/tearing
Small raw areas/divots that sometimes have white edges
Occasional ulcer-like lesions
Pain that can persist even when there are few visible lesions
Severe pain after even minor friction/trauma
I also get recurrent mouth ulcers and areas of painful/inflamed oral mucosa
I’ve had 2 vulvar biopsies and 1 biopsy in my mouth with active inflammation, and none have shown lichen sclerosus or another specific lichenoid disorder. The pathology has essentially shown nonspecific/general inflammation.
I’ve also been evaluated by multiple gynecologists and dermatology specialists. At different points, possibilities like IBD-related vulvar inflammation, erosive lichen planus, Behçet’s, and neuropathic pain have been considered, but nothing has really explained the whole picture.
Things I’ve tried
I feel like I’ve tried an enormous number of approaches at this point, including:
Multiple nerve-pain medications/neuropathic pain treatments
Topical lidocaine (which actually made the burning worse), ketamine/amitryptaline/cromolyn ointment
Tacrolimus
Oral ketotifen and cromolyn
Oral amitriptyline, pregabalin, JourvanX, gabapentin, sprovato all for pain
Hormonal/estrogen treatment and testosterone
Pelvic floor physical therapy
Baclofen
Colchicine for several months
5 different types of topical steroids
Opzelura
Dupixent
IBD medications and getting my underlying IBD under control
Dermatology and gynecology evaluations
Multiple biopsies
Anti inflammatory diet
Supplements
Despite all of this, the chronic pain never goes away, and I still periodically get episodes of ulceration, tearing, peeling, and significant inflammation.
The impact on my life has been huge. I haven’t had sex in about 3 years. It isn’t just that intercourse is uncomfortable — my baseline pain and the fear of triggering another severe flare have made sexual intimacy feel essentially impossible.
What makes this especially frustrating is that I can have significant pain even when testing doesn’t show a clear disease process, while at other times I have very obvious visible inflammation/skin damage.
I’m wondering if anyone here has experienced something similar — particularly:
Vulvar ulcers/tearing with biopsies that did not show lichen
Both vulvar AND oral mucosal inflammation
IBD-associated vulvar/oral inflammation despite the IBD being controlled
A combination of inflammatory and neuropathic pain
Severe vulvar pain that persists after the visible inflammation improves
A diagnosis that took years or multiple specialists to figure out
A doctor/specialist who was actually able to connect the dots
At this point I’m open to ideas I haven’t considered, because I’m honestly exhausted and feel like I’ve reached the end of the road with the usual approaches.
I’m struggling. Is anyone else dealing with lichen planus? I got diagnosed with it earlier this year. I used to have the most beautiful skin and now I’m plagued with these horrible legions and darkened pigmentation. It’s difficult to look at myself and not hate myself. I wonder if a man will ever deal with me knowing I struggle with this skin condition.
I just got informed I have OLP. The ache was really bad, have bumps all over the back of my tongue, white web on my cheek ...
Hoping there is some natural remedies I can do since I'm already taking other medications to exist.
Thank you.
I’ve had biopsy-confirmed oral lichen planus and have basically been in an active flare for about 2.5 years. Recently I’ve started getting immediate irritation/burning from foods that never bothered me before: tomatoes, red meat, and now cubed cheese and my lips have started burning too. Yogurt and shredded cheese haven’t seemed to bother me. Has anyone else suddenly developed new food triggers after having OLP for a while?
Also, has anyone with active OLP/inflammation gotten braces or Invisalign? My dentists had been recommending orthodontics, but now that I have OLP they’re concerned about irritating my mouth further and don’t want to do it. I’m curious if anyone has successfully had braces or Invisalign while their OLP was still active and what your experience was.
It's so intense I'll itch it in my sleep. Mine is on my ankles and often I'll scratch and it ends up bleeding too which sucks. Anything I've tried the moment I take it off it's usually itchy again. I can't sleep with ointment on, it will just wipe off all over my bed.