r/NicotinamideRiboside

Hi everyone,

I am currently looking into NAD+ precursors to help optimize egg quality for trying to conceive (TTC). My main goal is to support chromosomal stability and reduce the risk of aneuploidies (errors in chromosome division).

I’ve been reading up on the options, and I’m torn between NMN and NR:

• NMN seems to have strong laboratory data specifically showing a significant reduction in aneuploidy rates in older oocytes, making it feel like a very direct option for chromosomal division.
• NR, on the other hand, seems to show excellent human data regarding oral bioavailability and how effectively it raises NAD+ levels in the body, which is great for overall cellular energy.

I’m trying to figure out the best practical approach and would love to hear your insights or what your clinics recommended:

1. Did you choose NR or NMN for egg quality prep, and what was your reasoning?
2. What daily dosage did you take?
3. Did you use an "all-in-one" complex (with things like CoQ10, Resveratrol, etc.) or did you prefer stacking pure bases to control the single absorption pathways?
4. Did your doctor advise you to stop immediately upon a positive pregnancy test?

Thanks in advance for sharing your protocols!

Tbh I was shocked and am trying to explain to her my concerns about supply chain and ordering from random site online. Am I an asshole?

Hello all
I just injected 40mg instead 20mg of NAD+
I’m a littleeee scared …. Overall I am ok it’s just now I have anxiety.
Any thoughts / tips ? ? Thanks !

Thinking of switching to Renue as it’s half the price where I am (Aussie). When I look this up in the subreddit I can only find three points:

1. A couple of people saying Renue worked better for them than Niagen
2. Several people saying Niagen has more science backing it - I know this is true but I want to hear about firsthand comparative experiences
3. One guy claiming that Renue is a shitty company without providing evidence

I have heard of the oral True Niagen, but now they are selling an injectable form. It is supposed to be superior to NAD+ because it freely passes into the mitochondria and then converts to NAD+. The oral is expensive and there doesn't seem to be a lot of positive user experience. I can't seem to find any information on the injectable. It's crazy expensive at around $300 for 5ml 100mg/ml. Still not sure how expensive that is because I can't find any kind of dosing protocols. Has anyone here tried it?

I've been trying to be more consistent with my health lately because balancing work, family responsibilities, and everyday stress has been leaving me completely drained. By the end of the day, I feel like I have very little energy left, and even after getting what should be enough sleep, I still wake up feeling sluggish. It's started affecting my productivity and even my motivation to stay active.

I've looked into different NAD+ supplements, but there are so many options that it's honestly overwhelming. Some claim to improve energy, focus, recovery, and healthy aging, while others seem to have mixed reviews.

Does anyone recommend a NAD+ supplement that genuinely gave you noticeable results after consistent use? I'm especially interested in hearing how long it took before you noticed improvements and whether the effects lasted over time.