r/RationalPsychonaut

How MDMA and LSD, edibles broke my cycle of despair and gave me a framework for harm reduction.

Hi, I want to share my story and the philosophy I developed to keep going when consciousness feels like a heavy burden.

I have always felt that we are basically nothing, like bacteria living in the sewers of a massive city. I believe in absolute nihilism, nothingness is my origin, and to it I will return. I didn't ask to come here, and if I had been given the choice before birth, I would have refused this unfair contract. To me, "consciousness" itself is not a gift, but rather a tragic mutation and a heavy curse that makes us realize the misery and absurdity of reality.

Because of this, I once reached the edge of the abyss, lost all justification to stay, and decided to end my life. But I decided to play my last card, experimenting with drugs. There, specifically with the drug Ecstasy, the cycle of despair was broken. The drug didn't create a new reality, but it revealed a "window" to me, it showed me that life has a beautiful face that can be enjoyed, exactly as depression had previously revealed its misery and tragedy. If it weren't for this experience, I would have ended my life early.

Since I was thrown into this existence against my will, I created my own rule for survival "reduce suffering and intelligently extract happiness". I practice a philosophy of careful enjoyment and harm reduction by using substances that suit me (like Cannabis, LSD, and MDMA) smartly, alongside supporting medications and rest periods, to extract every possible drop of happiness with the least damage. These "calculated chemical rewards" are what give me the reason and the fuel to fight and battle the daily tragedy of life. As long as my equation (Pleasure > Pain) continues, I do not want to return to nothingness at all. And if this equation were to fail due to an overwhelming circumstance outside my control, I might return to my decision to leave.

Despite my belief in the nihilism of existence, I have an extreme sensitivity to pain. I feel pity for all living creatures that share this curse with me. I still remember my deep sadness over a spider I killed one day at work, it pained me that I caused it ache. My moral philosophy boils down to not increasing the pain of the world, but rather reducing suffering as much as possible, for myself and others. Shared suffering makes me empathize with everything that possesses consciousness.

Despite the harshness and absolute absurdity of life, I sometimes consider myself lucky to have had the chance to experience this consciousness and these feelings. I have realized a great secret: life is extremely precious precisely because every passing second and every breath that goes out never returns. The transience of things is what gives them their value. I wish life were a paradise without pain, but since it isn't, I squeeze the moment because it will not repeat.

I live my daily life normally, I listen to music, go out with my friends, and play video games, but there is always an internal "voice" that never goes silent. It is my acute consciousness that watches me, analyzes everything, and constantly wonders about the secret of life. This continuous thinking is a very heavy guest that I sometimes wish to get rid of to live with the naivety of the rest, but in the end, it is "me".

I am not just someone escaping from reality, but an "experimenter" and a philosopher who refuses voluntary blindness. I am fully aware that I am just a passageway through which the days cross, but I have decided to be the leader of this passageway. I will continue to explore my consciousness, deconstructing the universe around me through different chemical lenses, enjoying the absurdity of this play until the curtain falls.

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u/Hot_Weather_9247 — 1 day ago

Can I use LSD after a psychotic episode?

I'm a 18-year-old Brazilian who enjoys psychedelics like magic mushrooms and acid. I've always smoked marijuana and used mushrooms and never had any problems, but two weeks ago, I had a bad trip with an acid called "pineapple" 400ug. I took half a pill. The trip up to the peak was good, but then I started having delusional thoughts like a new world order or aliens coming to abduct me. After that, I don't know what happened, but this "trip" didn't last for 5 days. For 5 days I thought everyone was watching me and that I could be kidnapped at any moment. If someone could explain what that was and tell me if I can or cannot use LSD, marijuana, or magic mushrooms after a while, I would be grateful.

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u/Objective_Award_1367 — 3 days ago
▲ 83 r/RationalPsychonaut+1 crossposts

Estrogen levels may dictate how the brain reacts to psilocybin, new animal study indicates

Study on rats indicates that estrogen may dampen the effect of psilocybin.

If this holds for humans, then a woman’s sensitivity to shrooms would fluctuate predictably through the menstrual cycle and would also be impacted by menopause etc.

Layperson article:

https://www.psypost.org/age-and-hormones-alter-how-rats-respond-to-psilocybin-2026-03-26/

Citation:
The study, “Age- and estrous-dependent effects of psilocybin in rats,” was authored by A.L. Zylko, R.J. Rakoczy, B.F. Roberts, M. Wilson, A. Powell, A. Page, M. Heitkamp, D. Feist, J.A. Jones, and M.S. McMurray.

u/wohrg — 3 days ago

Dosing question

Hi, im a regular tripper of LSD, with not as much experience on mushrooms, and am going to do a group trip with shrooms, but being Australian, we got subs instead of cubensis and dosing subs is very different from cubensis. My problem is I don’t know what I could compare it to, I’m planning on maybe taking 2 grams of subs but it’d be helpful to know what that would be compared to cubensis, as I am aware that subs are generally much stronger than cubensis, the stuff most you americans have and what most dosing charts are based on

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u/iforgotmypasswordss — 4 days ago

Anyone else find weed joints give you psychedelic effects?

The last few times I've smoked weed joints (only a few puffs each time) and I get time distortion, visual distortion with seeing patterns, not as intense as shrooms but definitely there. Also just heavy body load and restlessness.

I never have this experience with edibles, or vaping. It seems specifically only with joints for me that I feel this psychedelic experience.

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u/oatmilkielatte — 4 days ago

Shrooms Vs Weed

Hi all.

I have been considering taking shrooms due to the effects I’ve heard it has on creativity and euphoria. I am a musician and struggling badly with writers block and I feel that if I take some it could open up something I never knew I had.

Here’s the thing… I have a horrible experience with weed. I have tried edibles, flower, carts, and the latter and they are all the same horrible “trip”. I get extremely anxious and paranoid, and I lose touch with reality. Imagine you’re on your phone, about to go to bed and you didn’t realize you fell asleep for just a moment until you wake back up seconds later. That is my experience, but fully conscious the entire time. It is horrific and has basically traumatized me, hence why I am hesitant to take any other substances. I only drink socially and am a light smoker. I am also very physically active and give myself challenges to keep my cognitive in check.

I am in my 20s and want to experience stuff before I get too old. I feel like I am too scared but I have heard a lot of stuff about benefits of psychedelics.

Any advice?

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u/rubix_jelly3 — 6 days ago
▲ 1 r/RationalPsychonaut+1 crossposts

How is it that prominent DMT researchers like Andrew Gallimore describe DMT entity communication as if it is indecipherable when we're constantly reading and experiencing that so many of them can speak English?

Paging u/alieninsect

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u/la_throwaway_3 — 7 days ago
▲ 2 r/RationalPsychonaut+1 crossposts

Blind people tripping

Just got very curious. What kind of experience the blind people are living through on their psychedelic trips? How do they get the divine information? What is their trip like?

Thanks for the answers, guys.

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u/kristinajure — 7 days ago

Title: Total sensory deprivation under LSD in 1971 — examining the experience through neuroscience and the Page-Wootters mechanism for emergent time

In 1971, a young Vietnam vet took an unknown dose of LSD and lost all sensory perception — not reduced, gone. What remained was consciousness in a void, where he built a spatial environment through pure intention and arrived at ethical questions about creating aware beings, decades before AI researchers faced the same problem.

This essay starts with the neuroscience explanation (thalamocortical gating failure, cortical construction from internal resources) and acknowledges it may be sufficient. It then explores connections to the Page-Wootters mechanism for emergent time, the distinction between temporal metric and topology, time as accumulation rather than flow, and consciousness as a complementary pair to the void.

Nothing is presented as proof. The questions are the point.

Full essay on Medium: https://medium.com/@wes2020007/the-void-84471bcf0961

Also available at: talking-about-ai.com

medium.com
u/Actual_Interaction15 — 6 days ago
▲ 74 r/RationalPsychonaut+2 crossposts

I’ve finally published my memoir

In 2020-2021 the r/rationalpsychonaut community might’ve been the biggest community to help propel my story forward. At the time I was hosting my podcast about how ayahuasca changed my life. Now, 5-6 years later I’ve finally completed writing my memoir that encapsulates it all!

Please consider ordering a copy off of Amazon.

https://a.co/d/05Y4scDb

I want to personally thanks this community from the bottom of my heart.

Disclosure: I did use ai to collaborate for the cover art, not for my story.

u/CultivatingConnect — 10 days ago

What is your metaphysical view of reality and how have psychedelics shaped it?

I’m curious if psychedelics have shaped your metaphysical (or ontological) views? If so, has the noetic quality of mystical experiences induced by psychedelics played a role? Have you been shown visions that correlate or reflect certain philosophical views (e.g., substance dualism, the doctrine of anatta in Buddhism, animism, etc.)?

For me personally, I have had multiple experiences from various tryptamines and dissociatives that have informed my views of reality, but I have gone back to scientific theories to serve as a framework for interpreting them. I mostly have leaned towards an information-theoretic neutral monism or perhaps dual-aspect monism type of view that incorporates a process-based ontology (vs. substance) and elements of Madhyamaka Buddhism (Nagarjuna’s views) that reflect how I have come to view the nature of things. I’m curious what your views are!

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u/theemezz0 — 9 days ago
▲ 5 r/RationalPsychonaut+1 crossposts

My first trip is tomorrow.

I'm having my first DMT trip tomorrow. I am in astonishment in anticipation. The weight of what I'm about to experience is not lost on me. I am a psychonaut through and through, and I am a junkie for REALNESS and lucidity and SEEING reality and my own phenomenology, and I know I'm going to be utterly astonished. I can imagine it happening in the space I am in right now, the walls tearing open and me being thrust into the sky, AND ALL AS REAL AS THIS VERY SPACE I SEE BEFORE MY EYES RIGHT NOW. I am so so excited. THIS IS WHAT I LIVE FOR. I CANT WAIT TO SEE THIS. I love this shit so cosmically much, and I'm about to experience the creme del creme of experiences in 24 hours! Ughghhhh!!

I'm going to do 11mg of 2c-b to put me in the psychonaut vibe, and then as soon as I know I'm ready I'm going for waiting room or breakthrough level. Would love some loving energy from you angels to take with me tomorrow. ❤️ I'll share your love with the machine elves and let them know you guys said hello.

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u/WhereTFAreWe — 10 days ago