r/dupixent

I finally got into a allergist who actually listened to me and gave me answers I’ve been searching for, for 12+ years. They want to put me on dupixent every 2 weeks for 1 year.

What’s everyone’s experience with dupixent? Did it work? How long have you been using it? Side effects?

I’ve mostly gotten my eczema under control (meaning no full body flares or open oozing wounds) with diet & environment changes. So I’d say I’m a mild case as of today. I’m terrified of needles and am dreading the 2 week schedule. Please share your experiences! Good or bad.

Also has anyone successfully gone on dupixent and been able to have their food intolerances again? For reference I can’t have dairy without a flare up, but no major reaction during my allergy testing.

American here. I’ve read several other posts about how our the american insurance thugs are tricking and robbing us and then telling us it’s our own fault. They should literally all be in prison for life. I hate it here sometimes. So I’m not even going to bother detailing the saga of how I’ve just been financially raped by these criminals. My question is this: has anyone been able to buy dupixent in Canada or Mexico for a more reasonable price? I think I’m effed for 2026, but maybe next year I won’t have to start selling nudes if I can sort this out now.

[ Removed by Reddit on account of violating the content policy. ]

Hi everyone, I’m looking for some guidance from people who developed joint or tendon-related symptoms while being on Dupixent long term.
Specifically, I’m hoping to hear from people who had been on Dupixent for more than a year before symptoms started. Did anyone begin developing joint pain, stiffness, tendon pain, swelling, gait changes, or tenosynovitis months or even a year+ after starting Dupixent?
If yes:
What symptoms did you develop?
How long after starting Dupixent did they appear?
Did your doctors feel Dupixent triggered or unmasked inflammation?
Did stopping Dupixent help?
If you stopped it, how long did it take for symptoms to improve?
Trying to understand others’ experiences, especially delayed-onset joint/tendon symptoms after long-term use. Thank you so much.

I took my loading dose 4 weeks ago and felt great. 2 weeks later I took my 2nd dose. And I felt fine until about a week after my 2nd dose. I got nauseous, with a headache that wouldn't go away, super dizzy when I'd sit up or lay down, and aggressive eye twitching. It didn't feel great at all.

I'm due for my shot this Thursday but I'm scared to take it because of how I felt. Anyone else feel like this? I reached out to my derm as well but just wanted to see what others think.

taking Dupixent for eczema, but I have asthma and the myriad of other ailments Dupixent is used to treat. I’ve only just started and I feel like it’s just made everything worse! I‘m constantly coughing up gross gunk, my legs are covered in sores (eczema related) I know it’s going to take some time, but i’m wondering if it’s actually going to get better at this point, I feel like I'm not supposed to react this poorly to it. how long did it take for Dupixent to actually kick in for y‘all?

its been roughly 9 months on dupixent and it has literally changed my life, the only side effects i have gotten is a little bit of dry eye, mild eczema spread onto my back and hair fall. the side effects are minimal and don't affect me too much. i could not recommend this medication enough but i am worried about coming off of this medication, before it i had very very angry red, unbearably itchy skin which made my life literal hell and i am scared that i am going to relapse. anyone who has came off it please let me know how it was and if you weaned off of it

Dupixent MyWay introduced a new maximizer policy starting 12/1/2025: if an account is identified as having a maximizer program, they will only cover $200 per shipment.

My insurance in 2025 was BCBS with Express Scripts for prescription coverage, and Accredo was my specialty pharmacy. My 2025 plan did not have a maximizer program.

For 2026, Express Scripts no longer handled my prescription coverage, so my BCBS plan switched to a different pharmacy benefit manager. My new 2026 insurance plan does include a maximizer program, which was confirmed as the reason my account got flagged.

I’ve called Dupixent MyWay countless times, and this really seems to be a technical loophole that caused the bill.

Here’s the issue:

• Dupixent MyWay can use the survey request process (virtual debit card/copay assistance) to cover the December 2025 claim. However, the maximizer cap first needs to be removed by the Sanofi escalation support team.
• Starting 1/1/2026, the escalation team can instead use the rebate program for accounts with maximizer restrictions. But they refuse to remove the maximizer cap from my account because my 2025 and 2026 accounts are linked together.

Basically, even though I can prove my 2025 insurance did not have a maximizer program, Sanofi says they cannot remove the cap because it would affect my 2026 coverage. It seems like they never anticipated people having completely different prescription coverage between the two years.

I also contacted Express Scripts many times trying to get a Summary of Benefits document showing there was no maximizer in 2025. Since my account is now inactive, they say they cannot access or provide that document, and I also cannot download it from the website for the same reason. The only thing they can provide is an account statement.

I genuinely did not have a maximizer program in 2025, and it doesn’t feel fair that I’m being held responsible for this bill because of a system issue. I’ve already spent 20+ hours on calls and I’m still stuck dealing with the escalation team.

Has anyone experienced something similar or found a way to resolve it?

I started it this month. I took my third shot last Friday.! and I’ve noticed a lot more fatigue bone pain and acne and Im taking it for my EOE not for like eczema or asthma! So I’m just wondering if this is going away for y’all or maybe it's normal I don't know

**If this is the wrong sub, please let me know and I will be glad to delete. Also, I have a post op appointment on Friday so I will be talking to my doctor about this as well. Essentially, I am looking for feedback to consider prior to the meeting. I would like to be put on Dupixent for type 2 inflammation and wanted to guage the likihood based on these findings. I have not been formally diagnosed with type 2 inflammation by my rhinoloist.

Last week, I had sinus surgery:

-Bilateral functional endoscopic sinus surgery – frontal sinus;

-Bilateral functional endoscopic sinus surgery – ethmoid total;

-Right maxillary antrostomy with tissue removal;

-Bilateral sphenoidotomy with tissue removal;

-Submucous resection inferior turbinate bilateral

The biopsy report states "Bilateral Sinus Contents:

Mild chronic sinusitis with eosinophilia".

Are these biopsy findings indicative of Type 2 Inflammation with esophils? I guess I am worried the report says 'mild' verse something that might mean more severe.

What measures are considered to make a formal diagnosis of type 2 inflammation?

I had sinus surgery on a deviated septum with polyps removal 11 months ago.

Hi! My son currently takes one dupixent injection a month. One of our injections was left in the box at room temp (below 77°) for 24 hours, so I popped it back in the fridge when I saw it was out. I just read that doing that is not recommended. I called Sanofi and they couldn’t give me any direct answers as to whether that syringe will still be okay for next month’s injection or why it wouldn’t be. I plan to call the pharmacy next, but does anyone have any experience with this? Thank you!

Ciao a tutti. Oggi sono 28 giorni. E devo fare la terza dose .. per prurigo senza noduli su dermatite atopica. Ma.. nulla. Prima il prurito era migliorato dalla seconda dose sembro peggiorata. Il prurito è di nuovo più frequente (anche se non prendo più antistaminici) ma vivo reclusa in calzoncini e maglietta.. è tutto uguale e ho paura.. c'è qualcuno che come me non vedeva risultati e stava perdendo le speranze e poi ha iniziato a funzionare? Grazie in anticipo a chiunque vorrà rispondermi..e ❤️💋😇

Has anyone developed psoriasis during treatment with Dupixent for atopic dermatitis?

I’m using Dupixent and I’m in my 7th year of treatment, with zero side effects so far. For about a month now, I’ve had a single red plaque on my temple and flaky/scaly ears.