r/dupixent

it’s been a few months since ive posted anything about my severe eczema, but finally after months of back and forth with multiple different dermatologists, i was approved for dupixent.

i had my loading dose of the 2 injections today and was wondering how long it took to see results? also if anyone has advice on how to make the injection less painful! i just keep telling myself the 20 seconds of pain will be worth it over dealing with my severe eczema. any advice is appreciated!

I’ve been on Dupixent for about 6 months now and I’ve noticed something really unexpected…. I’ve gained at least 5kg, possibly more. I know weight gain isn’t listed as an official side effect of Dupixent, which is why I’m curious wether anyone else experiences this.

Before starting Dupixent, I was very lean build and had always struggled to gain weight. I could eat a lot and would basically stay the same weight. I always assumed I just had a very fast metabolism. Nothing significant has changed in my lifestyle, diet, exercise etc. but since starting Dupixent I’ve gradually gained around 5kg over the last 6 months.

I’m actually not upset about the weight gain at all, if anything, I’m kind of happy about it because gaining weight has always been difficult for me. I’m just curious about why this might be happening…

Has anyone else on Dupixent noticed unexpected weight gain, especially people who previously struggled to gain weight? If so, how much did you gain and and how long after starting Dupixent did you notice it?

I’ve had tattoos way before I started Dupixent, but has anyone gotten one while on it? I have an appointment for one but I was just curious because I haven’t had issues at all with my old tattoos.

Long-time eczema sufferer here. Dupixent has genuinely been a game-changer for a lot of us, but I've been thinking about the long-term picture more lately and got curious where others are at mentally.

A few questions I'd love to hear your honest takes on:

• Are you satisfied with where you're at on Dupixent? Full clearance, partial, still struggling?
• Is your plan to stay on it indefinitely? If your skin stays clear, do you ever think about stopping -- or does that feel too risky to even consider?
• If you have thought about rolling off, what does that actually look like to you? Are you waiting for something better to come along, hoping to taper down, or actively working toward it?
• Are you doing anything complementary in the meantime? Chinese medicine, dietary changes, gut health stuff, natural remedies, anything like that -- and do you feel like it's actually moving the needle or just something you're doing out of hope?

No judgment here either way -- I know some people feel like Dupixent is a permanent fixture and that's completely valid. Just genuinely curious how people are thinking about this.